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Instructions

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Instruction for use: Insulin Maxirapid WO-S

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ATX Code A10AB03 Pork insulin

Active substance Insulin soluble [pork monocomponent]

Pharmacological group

Insulins

Nosological classification (ICD-10)

E10 Insulin-dependent diabetes mellitus

Decompensation of carbohydrate metabolism, Diabetes mellitus, Diabetes insulin sugar, Diabetes mellitus type 1, Diabetic ketoacidosis, Insulin-dependent diabetes, Insulin-dependent diabetes mellitus, Coma hyperosmolar non-ketoacidotic, Labile form of diabetes mellitus, Violation of carbohydrate metabolism, Type 1 diabetes mellitus, Type I diabetes mellitus, Insulin-dependent diabetes mellitus, Type 1 diabetes mellitus

Composition and form of release

1 ml of solution for injection contains monocomponent pig insulin 40 IU; In bottles of 10 ml (400 IU (international unit)), in the box 1 bottle.

pharmachologic effect

Pharmacological action - hypoglycemic.

Interacts with specific membrane receptors, regulates the processes of phosphorylation of cellular proteins and promotes the utilization of glucose.

Clinical Pharmacology

The effect develops after 15-30 minutes, reaches a maximum after 2.5-5 hours, lasts 7-8 hours.

Indications

Insulin-dependent diabetes mellitus (type 1).

Contraindications

Hypersensitivity, insuloma.

Side effects

Urticaria, angioedema.

Interaction

The effect is enhanced: alcohol, beta-adrenolytic drugs, MAO inhibitors, salicylates, weaken - estrogens, lithium preparations, sympathomimetics, glucocorticoids, phenytoin.

Dosing and Administration

P / c, intravenously (intravenously) or IM (intramuscularly); The dose is selected individually. Diabetes mellitus type 1: subcutaneously (subcutaneously), 15-30 minutes before meals, 0.5 IU (international unit) / kg / day (day) in several receptions.

Diabetic coma and ketoacidosis: at the level of glycemia no more than 33.6 mmol / l - 1 IU (international unit) / kg, up to 56 mmol / l - 100 IU, more than 56 mmol / l - 200 IU (international unit) . The first half of the dose is given in / in, the second and the next - in / m.

In / in (intravenous) coma treatment: the initial dose is 8-10 IU (international unit), then 6-8 IU (international unit) / h.

Overdose

Symptoms: hypoglycemia, profuse sweat, tachycardia, anxiety, hand tremor, visual acuity, headache, disorientation, psychomotor agitation, delirium, stunning, loss of consciousness, convulsions.

Treatment: ingestion of 2-5 pieces or portions of sugar dissolved in water. In severe hypoglycemia - 1 mg glucagon sc (subcutaneously) or IM (intramuscularly), a solution of glucose IV (intravenously).

storage Conditions

In the dark place at a temperature of 2-8 C (do not freeze).

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.

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