Instruction for use: Hfemate P
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Dosage form: Lyophilizate for the preparation of a solution for intravenous administration
Active substance: Coagulation factor VIII
ATX
B02BD02 Coagulation factor VIII
Pharmacological group:
Coagulants (including factors of blood coagulation), hemostatics
The nosological classification (ICD-10)
D66 Hereditary factor VIII deficiency: Congenital insufficiency of factor VIII; Hemophilia; Hemophilia A; Hemophilia classical; Deficiency of antihemophilic factor of blood VIII; Deficiency of the coagulation factor VIII; Inhibitory form of hemophilia A; Bleeding at hemophilia A; Hereditary hemophilia; Hereditary anomalies of antihemophilic factor VIII; Failure factor VIII; Insufficiency of coagulation factor VIII; Acquired hemophilia; Coagulopathies are hereditary
Composition and release form
1 bottle with powder for the preparation of the injection solution contains 250, 500 or 1000 IU of anti-hemophilic factor YIII, complete with a solvent.
Pharmachologic effect
Mode action - Replenishing deficiency of coagulation factor VIII.
Indications for Hfemate P
Hemophilia A, congenital and acquired factor YIII deficiency.
Contraindications
Hypersensitivity, coagulopathy without factor VIII deficiency, pregnancy, lactation.
Side effects
Fever, hemolysis, the formation of antibodies to factor VIII, allergic reactions.
Dosing and Administration
IV, The dosage is determined by the degree of manifestation of the factor YIII deficiency, and also depending on the localization and severity of the bleeding. When 1 IU / kg body weight is administered, an increase in the activity of factor YIII by about 1% of the norm should be expected.
Storage conditions of the drug Hfemate P
At a temperature of 2-8 ° C.
Keep out of the reach of children.