Instruction for use: Heparin sodium + Benzocaine + Benzylnicotinate

Trade name of the drug – Heparin ointment

The Latin name of the substance Heparin sodium + Benzocaine + Benzylnicotinate

Heparinum natrium + Benzocainum + Benzylii nicotinas (genus. Heparini natrii + Benzocaini + Benzylii nicotinatis)

Pharmacological group:

Anticoagulants in combination

The nosological classification (ICD-10)

I80 Phlebitis and thrombophlebitis: Diseases of peripheral vessels; Inflammation of superficial veins; Inflammatory diseases of veins; Deep venous thrombophlebitis; The disease of veins; Disease of the veins of the lower extremities; Diseases of peripheral vessels; Migrating phlebitis; Insufficiency of veins of lower extremities; Exacerbation of chronic thrombophlebitis; Acute thrombophlebitis; Acute thrombophlebitis of superficial veins; Periphlebitis; Periflebit surface; Superficial inflammation of veins; Surface thrombophlebitis; Surface phlebitis; Thrombophlebitis; Deep vein thrombophlebitis; Thrombophlebitis superficial; Phlebitis; Phlebitis of deep veins; Phlebitis of superficial veins; Phlebopathy; Chronic thrombophlebitis; Endophlebitis

I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower limbs: Thrombophlebitis of superficial veins; Thrombophlebitis of superficial veins of legs; Thrombophlebitis of superficial veins; Phlebitis of superficial veins of legs; Inflammation of veins

I84 Hemorrhoids: Painful hemorrhoidal nodes; External hemorrhoids; Internal hemorrhoids; Inflammation of hemorrhoids; Exacerbation of hemorrhoids; Chronic bleeding hemorrhoids; Acute hemorrhoidal attack

I89.1 Lymphangitis: Lymphangitis; Lymphagitis; Lymphangitis acute

L98.4.2 * Trophic skin ulcer: Varicose ulcer; Varicose ulcers; Cutaneous ulcer; Non-healing ulcers; Trophic ulcer; Trophic ulcer of lower leg; Trophic skin lesions; Trophic after-burn ulcers; Trophic ulcers; Trophic skin ulcers; Ulcer of lower leg; Ulcer of skin; Ulcer of trophic skin; Ulcer on legs; Ulcerative necrosis of the skin; Ulcer of shin; Ulcer of the lower leg; Ulcers of lower extremities; Difficult healing ulcers

N61 Inflammatory Diseases of the Breast: Mastitis; Purulent mastitis; Non-sprout mastitis; Postpartum mastitis; Mastitis

O87.2 Hemorrhoids in the puerperium

R60.0 localised oedema: Allergic edema of the larynx; Local edema; Local edema; Local edema; Edema localized; Edema of the lower limbs; Edema caused by inflammation of the tendon sheaths; Edema after dental interventions; Swelling of the nasopharyngeal mucosa; Edema of the mucous membrane of the nasopharynx; Trauma of traumatic origin; Edema of traumatic nature; Edema with trauma; Post-traumatic swelling; Post-traumatic edema; Post-traumatic swelling of soft tissues; Traumatic edema; Edema of the oral cavity

T14.0 Superficial injury of unspecified area of the body: Abrasions; Scratch; Skin Wounds; Wounds of soft tissues; Hematoma; Hematoma of traumatic origin; Hematomas; Hematomas of muscles; Hematomas of soft tissues; Healing of the skin; Bruise; Bruising due to sprains and bruises; Microtrauma; External bruises; Small combing; Superficial hematoma; Superficial damage to the skin and mucous membranes; Subcutaneous hematoma; Post-traumatic hematoma; Post-traumatic disturbance of microcirculation; Skinness of the skin; Traumatic plexus lesions; Injury; Contusion of soft tissues; Joint bruise; Traumatic bruises; Traumatic injury; Primary treatment of surface contaminated wounds; Abrasion; Bruise

T14.9 Injury unspecified: Pain syndrome after trauma; Pain syndrome with injuries; Pain syndrome with injuries and after surgery; Pain in case of injury; Pain of a traumatic nature; Joint pain with injuries; Postoperative and post-traumatic pain; Pain in case of injury; Pain of traumatic origin; Severe pain syndrome of traumatic origin; Deep tissue damage; Deep scratches on the trunk; Closed injury; Minor Household Injuries; Minor skin damage; Violations of the integrity of soft tissues; Uncomplicated trauma; Extensive traumatic injury; Acute pain syndrome of traumatic origin; Edema with trauma; Postponed sports injuries; Post-traumatic pain; Soft tissue injuries; Joint wounds; Sports injuries; Injury; Traumatic pain; Traumatic pains; Traumatic infiltrate; Injuries to sports

T80.1 Vascular complications associated with infusion, transfusion and medical injection: Microvascular hemorrhages with blood transfusions

Model clinical-pharmacological article 1

Pharmacotherapy. Combination drug for external use, the effect of which is due to the properties of its constituent components. Anticoagulant direct action. Gradually released from the ointment, heparin sodium reduces the inflammatory process and has an antithrombotic effect. Promotes resorption of existing ones and prevents the formation of new blood clots. It blocks the synthesis of thrombin, reduces the aggregation of platelets. Oppresses the activity of hyaluronidase, activates the fibrinolytic properties of the blood. Benzyl ester of nicotinic acid expands the surface vessels, facilitating the absorption of heparin. Local anesthetic benzocaine reduces the severity of pain. When applied to the skin has a local analgesic effect.

Indication. Thrombophlebitis of superficial veins (prevention and treatment), postinjection and postinfusion phlebitis, external hemorrhoids, inflammation of postpartum hemorrhoids, trophic ulcers of the lower leg, elephantiasis, superficial periphlebitis, lymphangitis, superficial mastitis, localized infiltrates and edema, trauma and bruises (incl. Muscle tissue, tendons, joints), subcutaneous hematoma.

Contraindications. Hypersensitivity, ulcerative-necrotic processes, violation of the integrity of the skin.

Carefully. Thrombocytopenia, increased bleeding.

Dosing. Outwardly. The ointment is applied in a thin layer on the affected area (0.5-1 g per 3-5 cm section) and gently rubbed into the skin 2-3 times daily until the inflammation disappears, on average 3 to 7 days. The possibility of a longer treatment is determined by the doctor.

In thrombosis of external hemorrhoids, rectal tampons are used, the ointment is applied to a coarse or linen pad that is applied directly to the thrombosed nodes and fixed. Ointment should be applied daily, until the symptoms disappear, on average 3-14 days. For the same purpose, you can use a tampon soaked in ointment, which is injected into the anus.

Side effect. Hyperemia of the skin, allergic reactions.

Interaction. Do not prescribe locally with NSAIDs, tetracyclines, antihistamine drugs.

Special instructions. Do not apply to open wounds, if there are purulent processes.

The use of ointment is not recommended for deep venous thrombosis.