Instruction for use: Fastum

Active substance Ketoprofen

ATX code M02AA10 Ketoprofen

Pharmacological group

NSAIDs - Propionic acid derivatives

Composition and form of release

Gel for external use 2.5% 100 g

ketoprofen 2.5 g

auxiliary substances: carbomer 940; ethanol; Neroli oil; lavender oil; diethanolamine; distilled water

in tubes of aluminum for 30 or 50 grams, in a box of a cardboard 1 tube.

Description of dosage form

A colorless, almost transparent gel with a pleasant smell, non-greasy to the touch.

Characteristic

NSAIDs (non-steroidal anti-inflammatory drugs).

pharmachologic effect

Pharmacological action - anti-inflammatory, analgesic.

The mechanism of action of the drug is associated with inhibition of biosynthesis of PG.

Pharmacodynamics

Fastum gel shows local analgesic, anti-inflammatory, antiexudative action with symptomatic treatment of diseases of joints, tendons, ligaments, muscles, skin, veins, lymphatic vessels and lymph nodes. With articular syndrome, weakening of pain in joints at rest and during movement, reduction of morning stiffness and swelling of the joints.

Pharmacokinetics

With topical application in the form of a gel, it is absorbed extremely slowly and practically does not accumulate in the body. Bioavailability of the gel is about 5%. The dose of 50-150 mg after 5-8 hours creates a level in the plasma of 0.08-0.15 μg / ml.

Indications

Inflammation and pain sensations of different etiology: rheumatism, osteoarthritis of various localization, osteochondrosis, ankylosing spondylitis, gout attack, rheumatoid arthritis and periarthritis; Bursitis, tendonitis, tendosinovitis, synovitis; sciatica, myalgia, radiculitis; bruises, dislocations, stretching of muscles; phlebitis, thrombophlebitis of superficial veins, lymphangitis.

Contraindications

Individual hypersensitivity to ketoprofen, acetylsalicylic acid or other NSAIDs (including in the anamnesis), gastrointestinal diseases in the acute phase, marked violations of kidney and liver function, blood disorders (leukopenia, thrombocytopenia, hemocoagulation disorders), pregnancy, breast feeding, children under 15 years.

pregnancy and lactation

Contraindicated in pregnancy. For the duration of treatment, breastfeeding should be discontinued.

Side effects

Possible allergic reactions from the skin (itching, urticaria) with prolonged use.

Dosing and Administration

On skin, apply a small amount of gel (3-5 cm) a thin layer on the skin above the focus of inflammation and lightly rub 1-2 times a day. The duration of the course of treatment without consulting a doctor should not exceed 14 days.

Precautionary measures

If any side effects occur, discontinue use and consult a doctor.

Avoid getting the gel on the damaged surface of the skin, open wounds, eyes and other mucous membranes.

Before using the drug should consult with a doctor if the liver and / or kidney function, gastrointestinal diseases in history; bronchial asthma, rhinitis, hives, polyps of the nasal mucosa; heart failure.

You should consult your doctor before using the gel while taking other medications.

Storage conditions

In the dark place at a temperature of 15-25 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use after the expiry date printed on the package.