Instruction for use: Diprogentata

Active substance Betamethasone + Gentamycin

ATX code D07CC01 Betamethasone in combination with antimicrobials

Pharmacological group

Glucocorticosteroids in combinations

Nosological classification (ICD-10)

L20 Atopic dermatitis

Itchy atopic eczema, Common neurodermatitis, Allergic skin diseases, Allergic skin diseases of non-infectious etiology, Allergic skin diseases of non-microbial etiology, Allergic skin diseases, Allergic skin lesions, Allergic manifestations on the skin, Allergic dermatitis, Allergic diathesis, Allergic itching dermatosis, Allergic Skin Disease, Allergic skin irritation, Dermatitis allergic, Atopic dermatitis, Dermatosis allergic, Diathesis exudative, Skin Allergic Disease, Skin allergic reaction to medicinal and chemical preparations, Skin reaction to medication, Skin and allergic disease, Acute eczema, Chronic atopic dermatitis, Exudative diathesis, Itching allergic dermatosis

L21 Seborrheic dermatitis

Dermatitis seborrheic, Increased sebum separation, Seborrheic Eczema, Seborrheic dermatitis of the scalp, Seborrheic pyodermatitis, Seborrhea, Eczema seborrheic

L26 Exfoliative dermatitis

Dermatitis exfoliative, Exfoliative dermatitis generalized

L29.3 Anogenital pruritus, unspecified

Itching in the genital and anus, Anal itching, Anogenital itching, Genital itching, Anogenital itching, Itching of the anorectal region, Itching of the vulva, Itching of the genitals, Perianal dermatitis

L30.1 Dyshidrosis [pomfolix]

Skin dyshidrosis, Pomfolix, Eczema dysgidrotic, Dyshidrotic eczema, Infected dyshidrosis, Dyshidrosis, Dyshidrotic dermatitis

L30.3 Infectious dermatitis

Microbial skin infections, Dermatitis with concomitant bacterial infections, Dermatitis in the presence of a bacterial infection or suspected of it, Infected eczema of external auditory canal, Secondarily infected dermatosis, Erythema migrans, Secondarily infected dermatoses , Dermatitis re-infected, Infectious dermatitis, Dermatitis infected, Dermatoses complicated by a secondary infection, Dermatoses complicated by primary and secondary infection, Dermatoses complicated by primary and / or secondary infection, Infected eczema, Infected dermatitis, Infected dermatosis, Migrating erythema, Microbial eczema, Chronic migratory erythema, Eczema is infected, Erythema Migrating, Bacterial dermatitis, Erythema migratory chronic, Superinfectant dermatitis, Necrolytic Migrating erythema

L30.9 Dermatitis, unspecified

Allergic dermatoses complicated by a secondary bacterial infection, Anal eczema, Bacterial maturation, Varicose Eczema, Venous dermatitis, Inflammation of the skin, Inflammation of the skin upon contact with plants, Inflammatory Skin Diseases, Inflammatory skin reactions, Inflammatory processes of the skin, Hypostatic dermatitis, Fungal Eczema, Fungal dermatosis, Dermatitis, Dermatitis is stagnant, Dermatitis and eczema in the anal area, Dermatitis acute contact, Perianal dermatitis, Dermatosis, Dermatosis of the scalp, Dermatosis of psoriasis, Dermatosis with persistent itching, Dermatoses, Dermatoses itchy, Other itching dermatoses, Significant eczematous manifestations, Itching with, dermatoses, Itching eczema, True eczema, Skin reaction to insect bites,Skin itching with dermatosis, Constitutional eczema, Weeping eczema, Drowsing inflammatory skin disease, Dying Infectious-Inflammatory Skin Disease, Non-allergic dermatitis, Nummular eczema, Acute contact eczema, Acute inflammatory skin disease, Acute dermatosis, Acute severe dermatosis, Perianal dermatitis, Superficial dermatosis, Subacute Contact Eczema, Simple dermatitis, Occupational dermatitis, Psychogenic dermatosis, Bubble dermatitis of newborns, Pustular eruptions, Irritation and redness of the skin, Low-flammable eczema, Dry atrophic eczema, Dry eczema, Toxic dermatitis, Ear eczema like dermatitis, Chronic eczema, Chronic dermatosis, Chronic common dermatosis, Scaly papular dermatosis, Eczema, Eczema anal region, Eczema of the hands, Eczema Contact, Eczema lichenized, Eczema Nummular, Eczema acute, Eczema acute contact, Eczema subacute, Eczematous dermatitis, Eczema-like rashes, Ecome exogenous, Endogenous eczema, Gluteal dermatitis, Restricted itchy dermatitis

L40 Psoriasis

Chronic psoriasis with diffuse plaques, Generalized psoriasis, Psoriasis of the scalp, Psoriasis of the scalp, Generalized form of psoriasis, Psoriasis dermatitis, Psoriasis complicated by erythroderma, Invalidative psoriasis, Isolated psoriatic plaque, Exfoliative psoriasis, Psoriatic Erythroderma, Psoriasis with eczematosis, Hyperkeratosis in psoriasis,Inverse psoriasis,Psoriasis eczematous, Dermatosis of psoriasis, Psoriasis of the genitals, Psoriasis with lesions of hairy areas of skin, Erythrodermal psoriasis, Chronic psoriasis of the scalp, Chronic psoriasis, Ordinary psoriasis, Refractory psoriasis, Kebner phenomenon, Scaly lichen

L43 Red Leaf Flat

Lishay Wilson, Erosive-ulcerative form of red flat lichen, Warty forms of red lichen, Red lichen, Flat lichen, Kebner phenomenon

L56.2 Photocontact dermatitis [berloque dermatitis]

Photoallergic contact dermatitis

Composition and form of release

Ointment 1 g

Betamethasone (base) 0.5 mg

(In the form of betamethasone dipropionate 0.64 mg)

Gentamicin (base) 1 mg

(In the form of gentamycin sulfate)

Auxiliary substances: paraffin liquid; Petroleum jelly white

In tubes of 15 g; In the box 1 tuba.

Cream 1 g

Betamethasone (base) 0.5 mg

(In the form of betamethasone dipropionate 0.64 mg)

Gentamicin (base) 1 mg

(In the form of gentamycin sulfate)

Auxiliary substances: petrolatum white; Cetostearyl alcohol; Paraffin liquid; Polyethylene glycol monomethyl ether; Sodium phosphate monohydrate; Chlorocresol; phosphoric acid; purified water

In tubes of 15 g; In the box 1 tuba.

Description of dosage form

Ointment. A soft consistency of almost white color is a homogeneous ointment.

Cream. Soft consistency white homogeneous cream.

pharmachologic effect

Pharmacological action - anti-inflammatory, antibacterial, antiallergic, antipruritic.

It inhibits the release of cytokines and inflammatory mediators, induces the formation of lipocortins, reduces the metabolism of arachidonic acid, inhibits the growth of Gram-positive and Gram-negative microorganisms, incl. Staphylococci, resistant to penicillin, protea, E. coli, Salmonella, etc.

Indication

Psoriasis, contact and atopic dermatitis (children's eczema, allergic dermatitis), neurodermatitis, lichen planus, eczema (coins, hands, eczematous dermatitis), intertriginous dermatitis, dyshidrosis, seborrheic dermatitis, exfoliative and sunny dermatitis, itching of the anus and external genitalia .

Contraindications

Hypersensitivity.

pregnancy and lactation

In large doses and for a long time is contraindicated.

Side effects

Burning, itching, irritation and dryness of the skin, folliculitis, hypertrichosis, acne vulgaris, hypopigmentation, perioral dermatitis, allergic contact dermatitis, systemic side effects, incl. Oppression of the adrenal cortex. When using occlusive dressings - maceration and skin atrophy, secondary infection, sweating, striae. Children - oppression of the hypothalamic-pituitary-adrenal system, Cushing's syndrome, linear growth retardation, lag in weight gain, increased intracranial pressure.

Dosing and Administration

Outwardly. Apply a thin layer on the affected skin, without rubbing, 2 times a day - morning and evening. In some patients, it is possible to achieve a satisfactory effect with a single application of the drug.

Precautionary measures

It should be borne in mind that systemic absorption increases if large areas of the skin are treated or occlusal dressings are used.

Storage conditions

At a temperature of 2-30 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use after the expiry date printed on the package.