Instruction for use: Diamidazepam
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Trade name of the drug – Diamidazepam
International name of the drug: Diamidazepam
Active substance: Hydrazinecarbonylmethylbromphenyldihydrobenzadiazepine
Dosage Form: tablets
Composition:
1 tablet contains 20 mg Hydrazinecarbonylmethylbromphenyldihydrobenzadiazepine. 10 pieces. - Packings tablets planimetric (3) - packs cardboard. 30 pcs. - Banks polymeric (1) - packs cardboard.
Pills. 1 tablet contains 50 mg Hydrazinecarbonylmethylbromphenyldihydrobenzadiazepine. 10 pieces. - Packings tablets planimetric (3) - packs cardboard. 30 pcs. - Banks polymeric (1.) - Packs cardboard
Pharmacotherapeutic group:
Tranquilizer (anxiolytic);Anxiolytic (tranquilizer).
Pharmacological Properties
Pharmacodynamics.
Anxiolytic (tranquilizer) benzodiazepine. It has also anticonvulsant, muscle relaxant and central nootropic action. It enhances the inhibitory effect of GABA in the central nervous system by increasing the sensitivity of the GABA-receptor mediator. Stimulates the benzodiazepine receptors, reduces the excitability of the subcortical brain structures inhibits polysynaptic spinal reflexes. The anxiolytic effect is to reduce the emotional stress, anxiety, weakening, fear, anxiety; sedation - in relation to symptoms of neurotic origin:. anxiety, fear on productive symptoms of psychotic genesis (acute delusional, hallucinatory, affective disorders) has practically no effect, it is rarely observed decrease in affective intensity, delusional disorders. Unlike other benzodiazepines has an activating effect.
Indications for Diamidazepam
- Logoneurosis;
- Vegetative lability (including diencephalic pathology);
- Migraine;
- Neurotic and neurosis-like states (anxiety, fear, irritability, emotional lability, insomnia, personality disorder);
- Alcohol withdrawal syndrome, alcoholism (comprehensive treatment).
Contraindications of Diamidazepam
- Chronic renal failure;
- Myasthenia gravis;
- liver failure;
- Hypersensitivity;
- Pregnancy;
- Lactation.
Precautions: open-angle glaucoma
Dosage and Administration of Diamidazepam
Inside, at 20-50 mg 3 times / day. If necessary, the dose is gradually increased until a therapeutic dose effects. Average dose in the treatment of patients with neurotic and neurotic disorders - 60-150 mg / day, for migraines and logoneuroses - 40-60 mg / day. To treat alcohol withdrawal initial dose - 50 mg, the average daily dose - 150 mg; the maximum daily dose - 500 mg. Duration of treatment - from several days to 1-2 months, the duration - is determined by the patient and the drug.
Side effect of Diamidazepam
CNS: drowsiness, weakness, myasthenia gravis, slowing of mental and motor reactions, addiction, drug addiction, decreased ability to concentrate, unsteadiness of gait, a violation of short-term memory.
Other: indigestion, reduced potency and / or libido, dysmenorrhea, allergic reactions.
Overdose of Diamidazepam
Dry mouth, constipation, urination disorders; drowsiness (in the elderly).
Cautions when receiving Diamidazepam
Effects on ability to drive vehicles and management mechanisms In the period of treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Interaction Diamidazepam with other medicinal products.
It enhances the effect of ethanol on the CNS, hypnotics, antipsychotics (neuroleptics), opioid analgesics.
Storage conditions
In the dark place at a temperature no higher than + 25 ° C.
Shelf life
3 years. Do not use after the date printed on the packaging.
Conditions of supply of pharmacies
On prescription.