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Instruction for use: Danol

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ATX Code G03XA01 Danazol

Active substance: Danazol

Pharmacological group

Hormone Hypothalamus, Hypophyse, Gonadotropin und deren Antagonisten

Nosological classification (ICD-10)

E30.1 Premature puberty

Premature puberty, Premature sexual development, Premature puberty in girls, Early puberty, Primary premature puberty

N60.1 Diffuse cystic mastopathy

Benign cystic change in mammary glands, Cystic fibrosis mastopathy, Fibrous-cystic mastopathy, Pre-cancerous condition of mammary glands, Benign mammary gland disease, Benign breast tumor

N62 Hypertrophy of the breast (breast) gland

Gynecomastia, Hypertrophy of the mammary glands, Macromastia

N80 Endometriosis

Endometrioid endometriosis

N92 Abundant, frequent and irregular menstruation

Metromenorragii, Menorrhagia, Menorrhagia primary, Polymenorea, Idiopathic menorrhagia, Menorrhagia, Functional metronormorragia, Primary menorrhagia

N92.2 Abundant menstruation in the puberty period

N94.3 Premenstrual tension syndrome

Pronounced premenstrual syndrome, Menstrual psychosomatic disorder, Menstrual syndrome, Premenstrual tension, Premenstrual status, Premenstrual period, Premenstrual syndrome, Menstruation syndrome

N96 Habitual miscarriage

Miscarriage habitual, Habitual abortion, Habitual miscarriage

N97 Female infertility

Female infertility in anovulation, Hyperprolactinemic infertility, Hyperprolactinaemia with infertility, Endocrine infertility, Infertility due to hypothalamic-pituitary dysfunction, Infertility infertility, Infertility, Infertility on the background of hyperprolactinaemia, Functional infertility, Marriage is infertile, Infertility of ovarian genesis, Stimulation of the growth of a single follicle

Composition

1 hard capsule contains 100 mg or 200 mg of danazol; In a blister 10 pcs., In a box of 10 blisters.

pharmachologic effect

The pharmacological action is antigonadotropic.

Suppresses the production of pituitary gonadotropic hormones (LH and FSH) in men and women; Oppresses the activity of the ovaries, inhibits ovulation, causes atrophy of the endometrium.

Indication

Endometriosis and the resulting infertility, mastopathy, primary menorrhagia, premature puberty in girls, macromastia, gynecomastia, premenstrual syndrome.

Contraindications

Porphyria.

pregnancy and lactation

Contraindicated. At the time of treatment should stop breastfeeding.

Side effects

Dyspepsia, increased intracranial pressure, dizziness, headache, agitation, seizures, alopecia, fluid retention in the body, weight gain, hot flashes, breast size reduction, liver dysfunction, seborrhea, acne, hirsutism, nausea, nervousness, pain in the body. Back, cramps, cholestatic jaundice.

Interaction

Enhances the effect of anticoagulants and carbamazepine, may increase the need for insulin.

Dosing and Administration

Inside, adults - 200-800 mg 2-4 times a day, the course - 6 months; Children - from 100 to 400 mg / day.

storage Conditions

In a dry place, at a temperature below 25 C.

Keep out of the reach of children.

Shelf life

Capsules are solid 100 mg - 5 years.

Capsules are solid 100 mg - 3 years.

Capsules are solid 200 mg - 5 years.

Capsules are solid 200 mg - 3 years.

Do not use after the expiry date printed on the package.

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