Instruction for use: D-Panthenol

Active substance Dexpanthenol

ATX code D03AX03 Dexpanthenol

Pharmacological group

Regenerants and reparants

Composition

Ointment for external use 1 g

active substance:

dexpanthenol 50 mg

auxiliary substances: phenonip - 4 mg; lanolin - 160 mg; white beeswax - 50 mg; paraffin white soft - 210.8 mg; Dimethicone - 5 mg; emulsifier Lanette SX - 20 mg; propylene glycol 20 mg; butylhydroxyanisole 0.1 mg; butylhydroxytoluene 0.1 mg; decamethylcyclopentasiloxane 20 mg; magnesium sulfate heptahydrate - 5 mg; Protein B - 295 mg; purified water - 160 mg

Description of dosage form

Ointment: homogeneous, light yellow color, with a characteristic smell of lanolin.

pharmachologic effect

Pharmacological action - dermatoprotective.

Pharmacodynamics

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid - water-soluble vitamin B group - is a component of coenzyme A. It stimulates the regeneration of the skin, normalize cellular metabolism, increases the strength of collagen fibers. Increased demand for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated for by local application of D-Panthenol.

Optimum molecular weight, hydrophilicity and low polarity make it possible to penetrate all layers of the skin. It has a regenerating, weak anti-inflammatory effect.

Pharmacokinetics

When topical application is rapidly absorbed and converted to pantothenic acid, binds to plasma proteins (mainly with beta-globulin and albumin).

Indications

violating the integrity of the skin, caused by mechanical, chemical, thermal factors, or after surgery (burns of various origins, including solar, scratches, abrasions, sores, bedsores, poorly healing skin grafts, aseptic surgical wounds);

inflammatory processes on the skin (dermatitis, furuncles, trophic ulcers of the lower extremities);

care for the skin around the tracheostist, gastrostom and colostrum;

treatment and prevention of the effects of the adverse effects on the skin of environmental factors (cold, wind, dampness), diaper dermatitis, minor scratches and irritation after exposure to the sun, UV and X-rays, treatment and prevention of diaper rash in children;

cracks and inflammation of the nipples of the breast in nursing mothers;

treatment and protection of dry skin - as a source of neutral fats and dexpanthenol.

Contraindications

Hypersensitivity to one of the components of the drug.

pregnancy and lactation

D-Panthenol ointment for external use can be used during pregnancy and lactation.

Side effects

Side effects are extremely rare. Minor allergic reactions are possible.

Interaction

The interaction of D-Panthenol ointment with other drugs for external use is not established.

Dosing and Administration

Locally. Ointment is applied 2-4 times a day (if necessary more often). Apply a thin layer on the affected area of the skin, lightly rubbing. In case of application on the infected skin surface, it should be pretreated with any antiseptic.

In nursing mothers: lubricate the surface of the nipple with ointment after each breast-feeding.

Infants: Apply ointment after each change of underwear or water treatment.

The duration of the use of the drug and the possibility of a repeat course of treatment depend on the individual characteristics of the clinic in the patient and are determined by the therapeutic effect achieved and the tolerability of the drug.

Overdose

Cases of overdose are not marked.

special instructions

Treatment of trophic ulcers and poorly healing skin grafts should be performed under the supervision of the attending physician. Do not apply to dying wounds.

The ability to influence the reaction rate when driving or working with other machinery. Does not affect.

Form of issue

Ointment for external use. For 25 g, 50 g of the drug in an aluminum tube, twice coated with a protective varnish, with a sealed hole and a plastic cap. The tube is placed in a cardboard box.

Conditions of leave from pharmacies

Without recipe.

storage conditions

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.