Instruction for use: Concor AM
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Active substance Bisoprolol + Amlodipine
ATX Code C07FB selective beta-blockers in combination with other antihypertensive agents
Pharmacotherapeutic group:
Antihypertensive drugs combined (.beta.1-blocker + selective blocker of the "slow" calcium channels (BCCI) [Beta-blockers in combination]
Antihypertensive drugs combined (β1-selective blocker blocker + "slow" calcium channels (BCCI) [Calcium channel blockers in combination]
The nosological classification (ICD-10)
I10 Essential (primary) hypertension
Hypertension, Arterial hypertension, Arterial hypertension crisis course, Essential Hypertension
Primary hypertension, Arterial hypertension, complications of diabetes, hypertension, The sudden increase in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial Hypertension, malignant Hypertension, Hypertonic disease, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, The aggravation of hypertensive disease, Transient hypertension, Isolated systolic hypertension
I15 Secondary hypertension
Arterial hypertension, complications of diabetes, hypertension, The sudden rise in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial hypertension, malignant hypertension, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, hypertensive crisis, The aggravation of hypertensive disease, Transient hypertension, hypertension, Arterial hypertension, Arterial hypertension crisis course, renovascular hypertension, symptomatic hypertension, renal hypertension, Renovascular hypertension, Symptomatic hypertension
Structure and Composition
Tablets 1 tab.
active substance:
amlodipine (amlodipine besylate a) - 5 mg (6.95 mg) and bisoprolol fumarate - 5 mg
amlodipine (amlodipine besylate a) - 10 mg (13.9 mg) and bisoprolol fumarate - 5 mg
amlodipine (amlodipine besylate a) - 5 mg (6.95 mg) and bisoprolol fumarate - 10 mg
amlodipine (amlodipine besylate a) - 10 mg (13.9 mg) and bisoprolol fumarate - 10 mg
Other ingredients: colloidal anhydrous silica - 1/2/2/2 mg; magnesium stearate - 1.5 / 3/3/3 mg; sodium carboxymethyl starch (type A) - 5/10/10/10 mg; MCC - 130.55 / 261.1 / 263.05 / 261.1 mg
pharmachologic effect
antihypertensive.
Dosing and Administration
Inside. The tablets should be taken in the morning, regardless of the meal, not liquid.
The recommended daily dose - 1 tab. certain dosage per day.
Selection and dosage titration for each patient carries a doctor during the appointment monocomponent preparations containing active ingredients that are part of the drug Konkor® AM.
The duration of treatment. Treatment with Konkor® AM is usually long-term therapy.
Special patient groups
Abnormal liver function. Patients with impaired hepatic function Amlodipine elimination may be delayed. Special dosing regimen for this patient group is not specified, but in this case the drug must be administered with caution. For patients with severely impaired hepatic function, the maximum daily dose is 10 mg bisoprolol.
Impaired renal function. Patients with impaired renal function, mild or moderate correction mode dosing is usually not required. Amlodipine is not displayed by dialysis. Patients undergoing dialysis, amlodipine should be administered with extreme caution. For patients with severe renal impairment (Cl creatinine <20 ml / min) the maximum daily dose is 10 mg bisoprolol.
Elderly patients. Older patients are usually prescribed dose of the drug. Caution is required only if the dose is increased.
Children. The drug is not recommended for use in children under the age of 18 years due to lack of efficacy and safety data.
Treatment should not be stopped abruptly, because this can lead to a temporary deterioration in the clinical condition. Especially the treatment should not abruptly stop in patients with CAD. It recommended a gradual reduction in dose.
release Form
Tablets of 5 mg + 5 mg; 10 mg + 5 mg; 5 mg + 10 mg; 10 mg + 10 mg. According to Table 10. placed in the blisters of a combined cold film (polyamide / aluminum foil / PVC) // Aluminum Foil. 3 bl. Table 10. packed in a cardboard box.
Conditions of supply of pharmacies
On prescription.
Storage condition
The temperature is not above 30 ° C.
Keep out of the reach of children.
shelf life
3 years.
Do not use beyond the expiration date printed on the package.