Instruction for use: Bromopride

The Latin name of the substance Bromopride

Bromopridum (genus. Bromopridi)

Chemical name

4-Amino-5-bromo-N- [2- (diethylamino) ethyl] -2-methoxybenzamide (as dihydrochloride)

Gross formula

C₁₄H₂₂BrN₃O₂

Pharmacological groups:

Antiemetic means and preparations

Serotonergic agents

Veterinary funds

The nosological classification (ICD-10)

K30 Dyspepsia: Fermentation dyspepsia; Hyperacid indigestion; Putrefactive indigestion; Dyspepsia; Dyspepsia of nervous origin; Dyspepsia in pregnant women; Dyspepsia fermentation; Dyspepsia putrefactive; Dyspepsia medication; Dyspepsia due to diseases of the digestive system; Dyspepsia due to impaired motility of the gastrointestinal tract; Dyspepsia due to unusual food or overeating; Dyspeptic phenomena during pregnancy; Dyspeptic Syndrome; Gastric indigestion; Delayed emptying of the stomach; Delayed digestion; Idiopathic indigestion; Acid dyspepsia; Disturbance of the upper GI tract motility; Indigestion; Nervous indigestion; Non-ulcer dyspepsia; The feeling of heaviness in the stomach after eating; Postprandial functional dyspepsia; The processes of fermentation in the intestine; Stomach upset; Gastrointestinal disorders; Digestive disorders; Disorders from the digestive tract; Stomach upset; Indigestion disorder; Indigestion in infants; Symptoms of dyspepsia; The syndrome of putrefactive dyspepsia; Syndrome of putrefactive dyspepsia in young children; Syndrome of insufficiency of digestion; Syndrome of nonulcer dyspepsia; Toxic indigestion; Functional dyspepsia; Functional indigestion; Chronic indigestion; Chronic episodes of dyspepsia; Essential dyspepsia; Dyspeptic disorder

K83 Other diseases of the biliary tract: Bile stasis

K94 * Diagnosis of digestive diseases: Hepatic and splenic scans; Visualization of the liver by invasive methods; Isotope scintigrams of the liver; Laparocentesis; Ultrasound examination of the liver; Magnetic resonance imaging of the liver; Computed tomography of the liver; Esophageal Manometry; Anoscopy; Visualization of the biliary tract; Ultrasonic visualization of the liver; Gastroscopy; Degassing of the intestine before diagnostic tests; Degassing of the intestine before X-ray examination; Gastrointestinal diagnostics; Diagnosis of bleeding from the small intestine; Diagnosis of focal pathology of the liver; Diagnosis of secretory ability and acid-forming function of the stomach; Diagnostic intervention on the large intestine; Duodenal sounding; Duodenoscopy; Instrumental studies of the abdominal cavity organs; Intraoperative cholangiography; Irrigoscopy; Examination of gastric secretion; Gastrointestinal tract examination; Study of acid-forming function of the stomach; Examination of secretory function of the stomach; Colonoscopy; Controlling the effectiveness of lithotripsy; Determination of the degree of hypersecretion in duodenal ulcer; Preparation for diagnostic tests; Preparation for X-ray and instrumental methods of abdominal examination; Preparation for X-ray and ultrasound examination of the abdominal organs; Preparation for X-ray or endoscopic examination of the digestive tract; Preparation for X-ray examination of the gastrointestinal tract with contrasting; Preparation for roentgenological examination of gastrointestinal tract with application of barium; Preparation for X-ray and ultrasound of the abdominal organs; Preparation for X-ray examination or ultrasound of the abdominal cavity organs; Preparation for ultrasound and radiographic examination of the abdominal cavity organs; Preparation for endoscopic examination of the lower parts of the colon; Preparation for endoscopic or roentgenologic examination of the lower intestine; Preparation of the lower GI tract for endoscopy; Preparation of the colon for instrumental and radiographic examinations; Preparation of the colon for X-ray and endoscopy; Recto-manoscopy; Rectoscopy; Radiography of the digestive tract; X-ray diagnosis of achalasia of the esophagus; X-ray diagnosis of diseases of the digestive tract; X-ray diagnostics of the digestive tract; Radiocontrast examination of bile ducts; Radiocontrast study of the digestive tract; Radiographic diagnosis of gastrointestinal tract; X-ray examinations of the digestive tract; X-ray examination of the duodenum and gallbladder; X-ray examination of the stomach; X-ray examination of the biliary tract and gallbladder; X-ray examination of the digestive tract; X-ray examination of the esophagus; Retrograde cholangiopancreatography; Retrograde endoscopic pancreatocholangiorentgenography; Sonography of the gastrointestinal tract; Splenoportography; Ultrasound of the abdominal cavity organs; Functional X-ray diagnostics for stomach diseases; Functional X-ray diagnostics for intestinal diseases; Cholangiography; Cholangiography in cholelithiasis; Cholangiopancreatography; Cholecystography; Esophagoscopy; Endoscopic retrograde pancreatography; Endoscopic retrograde cholangiopancreatography; Endoscopic interventions; Endoscopic examination of the digestive system; Endoscopic examination of the lower parts of the large intestine; Endoscopic examination of the digestive tract; Endoscopy; ERCPR; Panendoscopy

R11 Nausea and vomiting: Postoperative vomiting; Nausea; Vomiting; Vomiting in the postoperative period; Vomiting medication; Vomiting in the background of radiation therapy; Vomiting uncontrollable; Vomiting in radiation therapy; Persistent vomiting; Indomitable vomiting; Postoperative nausea; Vomiting with chemotherapy; Vomiting of the central genesis; Vomiting with cytotoxic chemotherapy; Persistent hiccups; Repeated vomiting

R14 Meteorism and related conditions: Bloating; Inflammation of the intestine; Severe flatulence; Gases in the postoperative period; Degassing of the intestine before diagnostic tests; Degassing of the intestine before X-ray examination; Gas retention; Excess formation and accumulation of gases in the gastrointestinal tract; Sour eructation; Flatulence; Meteorism with increased gas formation in the digestive tract; Flatulence in infants; Flatulence in newborns; Flatulence due to fatty or unusual food; The flatulence caused by the disease of the digestive system; Belching; Sensation of bloating; Sensation of stomach overflow; Increased gas formation; Enhanced gas generation and accumulation of gases in the gastrointestinal tract; Feeling of overfilling in epigastrium; A feeling of overflow of the stomach; Feeling of heaviness in the stomach; Increased gas formation in the gastrointestinal tract; Increased formation and accumulation of gases in the digestive tract

CAS Code

4093-35-0

Pharmacology

Pharmacological action - Antiemetic.

Has antidopaminergic activity. Affects the trigger zones of the brain stem. Has antiemetic effect for nausea and vomiting due to various gastrointestinal disorders: a decrease in the tone of the stomach and intestines, eructation, flatulence, gastritis, dyskinesia of the biliary tract, etc. It regulates the motility of the gastrointestinal tract, raises the tone and intensifies peristalsis.

Quickly absorbed from the digestive tract. Bioavailability is 50-70% (the effect of "first passage" through the liver) and easily passes the histohematological barriers, including the placental barrier, excreted, mainly with urine in the form of unchanged and conjugated substance and its metabolites; Can be secreted by lactating mammary glands. T1 / 2 - about 6 hours.

Application of substance Bromopride

Vomiting, nausea, hiccups: with toxemia, radiation therapy, diet disorders, taking some medications, with endoscopic and radiopaque methods of GIT.

Contraindications

Hypersensitivity, pregnancy, breastfeeding (at the time of treatment stop).

Side effects of Bromopride

Headache, dizziness, drowsiness, tinnitus, dry mouth, extrapyramidal symptoms, increased prolactin secretion, galactorrhea.

Routes of administration

Inside, IV or IM.

Precautions for the substance Bromopride

During treatment, one should refrain from potentially dangerous activities requiring increased attention.