Instruction for use: B-Insulin S.C. Berlin-Chemie

Active substance Insulin-aminoquinuride [pork monocomponent]

ATX Code A10AC Medium-acting insulins and their analogs for injectable administration

Pharmacological group

insulins

Nosological classification (ICD-10)Z31.1 Artificial insemination

E10 Insulin-dependent diabetes mellitus

Decompensation of carbohydrate metabolism, Diabetes mellitus, Diabetes insulin sugar, Diabetes mellitus type 1, Diabetic ketoacidosis, Insulin-dependent diabetes, Insulin-dependent diabetes mellitus, Coma hyperosmolar non-ketoacidotic, Labile form of diabetes mellitus, Violation of carbohydrate metabolism, Type 1 diabetes mellitus, Type I diabetes mellitus, Insulin-dependent diabetes mellitus, Type 1 diabetes mellitus

E11 Non-insulin-dependent diabetes mellitus

Acetonuric diabetes, Decompensation of carbohydrate metabolism, Diabetes insulin-independent sugar, Diabetes sugar type 2, Type 2 Diabetes, Non-insulin-dependent diabetes, Non-insulin dependent diabetes mellitus, Non-insulin-dependent diabetes mellitus, Insulin resistance, Insulin resistant diabetes mellitus, Coma lactobacillus diabetic, Violation of carbohydrate metabolism, Type 2 diabetes mellitus, Diabetes mellitus type II, Diabetes mellitus in adulthood, Diabetes mellitus in old age, Diabetes insulin-independent, Diabetes mellitus type 2, Sugar insulin-independent diabetes type II

pharmachologic effect

Pharmacological action - hypoglycemic.

Indication

Diabetes mellitus type I and II (in Type II diabetes, it is prescribed in combination with sulfonylurea derivatives if their isolated use is not effective).

Contraindications

Hypersensitivity.

pregnancy and lactation

Maybe.

Side effects

Hypoglycemia (up to hypoglycemic coma with loss of consciousness), allergic reactions: redness of the skin, itching, rashes, blisters, changes in visual acuity; Swelling; Locally: fatigue or proliferation of adipose tissue, necrosis.

Interaction

Hypoglycemia is enhanced by alcohol, acetylsalicylic acid, amphetamine, anabolic steroids, alpha and beta adrenoblockers, clofibrate, cyclophosphamide, fenfluramine, methyldopa, MAO inhibitors, tetracyclines, etc., weaken - chlorprotixen, diazoxide, diuretics, glucocorticoids, hormonal contraceptives, heparin, Isoniazid, lithium carbonate, nicotinic acid, phenothiazines, phenytoin, direct-acting adrenomimetics, tricyclic antidepressants. Thyroid hormones, salicylates, reserpine can both increase and decrease the effect. Reduces the tolerance of alcohol.

Dosing and Administration

P / to, for 45 minutes before a meal. Doses and duration of application are set individually. Usually adults - 0,3-0,8 U / kg / day in 2 doses (2 / 3-3 / 4 doses - before breakfast and the remainder - before dinner) or 1 time (when combined with oral antidiabetics) in adolescent Diabetes (in combination with short-acting insulin); With juvenile diabetes - at 0.7-0.8 U / kg / day. If necessary (in adolescence, at the stage of decompensation, in infections, in pregnancy, in obese patients), doses above 1 U / kg / day are possible. At the beginning of the course recommend the appointment of a single dose to adults - 8-24 units; Children and with a pronounced sensitivity to insulin or in combination with derivatives of sulfonylureas - less than 8 units. Exceeding a single dose of 40 units is not recommended.

Precautionary measures

Regular monitoring of blood sugar is required. With increased physical and mental stress, infections, vomiting, diarrhea, progressive diseases of the kidneys and liver, decreased function of the adrenal glands, pituitary gland and thyroid gland, lability of metabolism (significant fluctuations in blood sugar content), one should more often determine the level of glucose in the blood and adjust the dose. With caution appoint patients working at height and with vehicles.

storage Conditions

At temperatures not higher than 8 ° C (do not freeze).

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.