Instruction for use: Attapulgit (Attapulgitum)

Chemical name

Magnesium aluminosilicate hydrate colloid (natural purified mixture from the group of palygorskit minerals)

Pharmacological group

Antidiarrhoeic agents

Gastroprotectors

Adsorbents

Nosological classification (ICD-10)

A05 Other bacterial food poisoning

A09 Diarrhea and gastroenteritis of allegedly infectious origin (dysentery, bacterial diarrhea)

Bacterial diarrhea, Bacterial dysentery, Bacterial infections of the digestive tract, Bacterial gastroenteritis, Diarrhea bacterial, Diarrhea or dysentery of amoebic or mixed etiology, Diarrhea of infectious genesis, Diarrhea on the background of antibiotic therapy, Traveler's Diarrhea, Travelers diarrhea due to changes in diet and habitual diet, Diarrhea due to antibiotic therapy, Dysenteric bacteriocarrier, Dysenteric enteritis, Dysentery, Dysentery bacterial, Dysentery mixed, Gastrointestinal infection, GI tract infections, Infectious diarrhea, Infectious Disease of the GI tract, Infection of the gastrointestinal tract, Infection of the biliary tract and gastrointestinal tract, GI tract infection, Summer diarrhea, Nonspecific acute diarrhea of infectious nature, Nonspecific chronic diarrhea of infectious nature, Acute bacterial diarrhea, Acute diarrhea in food poisoning, Acute dysentery, Acute bacterial gastroenteritis, Acute gastroenterocolitis, Acute Enterocolitis, Subacute dysentery, Diarrhea chronic, Refractory diarrhea in AIDS patients, Staphylococcal enteritis in children, Staphylococcal enterocolitis, Toxic diarrhea, Chronic dysentery, Enteritis, Enteritis infectious, Enterocolitis

K58 Irritable Bowel Syndrome

Irritable bowel syndrome, Colitis spastic, Irritable bowel syndrome, Irritable bowel syndrome is a thin, irritable bowel syndrome, colon irritation syndrome, Symptoms of irritable bowel, Irritation of the stomach, Irritation of the intestinal mucosa, Irritated colon

K59.1 Functional diarrhea

Diarrheal syndrome, Diarrhea, Diarrhea with prolonged enteral feeding through the probem, Prolonged diarrheam Nonspecific diarrhea, Acute diarrhea, Diarrhea, Syndrome of diarrhea, Functional diarrhea, Chronic diarrhea, Diarrhea with an electrolyte balance disorder, Chronic diarrhea, Diarrhea of non-infectious genesis, Diarrhea after a gastroectomy, Diarrhea in children, Persistent diarrhea, Diarrhea (diarrhea), Enterocolitis of non-infectious origin

K63.8.0 * Dysbiosis

Violation of the intestinal flora, Correction of intestinal microflora, Normalization of intestinal microflora, Bacterial dysbiosis, Viral dysbiosis, Restoration of intestinal flora, Deficiency of lactic-acid and probiotic microorganisms, Diarrhea on the background of antibiotic therapy, Dysbacteriosis, Dysbacteriosis of the intestine, Intestinal dysbiosis, Disruption of normal intestinal microflora, Disbalance of intestinal microflora, Violations of the physiological flora of the large intestine, Disorders of the physiological flora of the small intestine, Helicobacteriosis

T78.4 Allergy, unspecified

Allergic reactions to insulin, Allergic reactions to insect stings, Allergic reactions similar to systemic lupus erythematosus, Allergic diseases, Allergic diseases of mucous membranes, Allergic diseases and conditions resulting from increased release of histamine, Allergic diseases of mucous membranes, Allergic symptoms, Allergic symptoms in the mucous membranes, Allergic reactions, Allergic reactions caused by insect bites, Allergic reactions, Allergic conditions, Allergic laryngeal edema, allergopathy, allergic conditions, Allergy, House dust allergy, Anaphylaxis, Cutaneous reactions to medications, Skin reaction to insect stings, Cosmetic allergy, Drug allergy, Acute allergic reaction, Laryngeal edema allergic genesis and background radiation, Food and drug allergy

Z72.4 Unacceptable diet and bad habits in nutrition

Inadequate nutrition, Irregular nutrition, Unbalanced diets, Dyspepsia due to unusual food or overeating, Long-term dietotherapy, Prolonged or low-calorie diets, Gastrointestinal disorders due to a violation of diet, Binge eating, Food poisoning, Errors in the diet, Compliance with diets, Compliance with a strict diet, Special diets

Pharmacology

Pharmacological action - adsorbing, enveloping, antidiarrheal.

Forms a thin film on the mucous membrane of the gastrointestinal tract. After oral administration, it is not absorbed into the digestive tract, it gradually progresses to the distal end of the digestive canal and is excreted. In the intestine adsorbs liquid, toxic and irritating substances, pathogenic pathogens and toxins formed by them, contributes to normalization of intestinal flora, reduces diarrhea, toxicosis, inflammatory phenomena. Promotes thickening of the liquid contents of the intestine, improves the consistency of the stool and reduces the number of bowel movements. Has astringent effect, favorably affects the irritated intestinal mucosa, reduces spasmic contractions of the musculature of the intestine.

Application of Attapulgite

Acute diarrhea of various origins, incl. when food poisoning, allergies or intolerance of certain food products, if the balance of the intestinal microflora is disturbed; irritation of the intestinal mucosa (as part of a combination therapy).

Contraindications

Hypersensitivity, intestinal obstruction, chronic diarrhea, diarrhea of parasitic genesis (including amoebic dysentery), acute dysentery with a stool with a dash of blood and fever (treatment with antidiarrheal drugs alone is not enough, antibiotics may be needed), children under 3 years old and elderly age (risk of loss of fluid and salts).

pregnancy and lactation

With caution (application experience is limited).

Side effects

Constipation (rarely), allergic reactions.

Interaction

Reduces the speed and completeness of absorption from the digestive tract of other drugs (antibiotics, digoxin, anticholinergics).

Routes of administration

Inside.

Precautions for Attapulgite

Treatment of children 3-6 years is strictly according to the doctor's prescription and under his supervision.

With an increase in body temperature, bloody stools or in cases of continued diarrhea after 2 days of treatment, it is necessary to clarify the diagnosis with the help of clinical and bacteriological studies.

If diarrhea and associated loss of fluid requires oral treatment with solutions for rehydration, it is performed primarily (especially in children and elderly patients), regardless of attapulgite treatment.

With diarrhea, presumably parasitic genesis, the use of antidiarrheals can make it difficult to recognize the etiology of the disease; when suspected of the parasitic nature of diarrhea, a feces analysis should be performed before attapulgite treatment begins.

It should be borne in mind that antidiarrhoeal adsorbents mask the loss of fluid, therefore, when there are signs of dehydration (dry mouth, thirst, reduced urine output, dizziness, etc.), rehydration therapy is necessary.