Instruction for use: Atenolol Belupo

Trade name of the drug – Atenolol Belupo

Dosage Form: tablets

Active substance: Atenololum

ATX

C07AB03 Atenolol

Pharmacotherapeutic group: Beta-blockers

Composition (per tablet): atenolol 25 mg, 50 mg, 100 mg

Excipients:

Tablet Core: MCC, lactose monohydrate, povidone, corn starch, talc, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate

coated tablet: hypromellose 5 cP, hypromellose 15 cps, talc, titanium dioxide, disodium edetate dihydrate, carnauba wax (for the 100 mg tablets)

in packages of cellular contour 14 (100 mg) and 30 ps .; a stack of cardboard packaging 1 or 2.

Pharmacological Properties of Atenolol Belupo

Pharmachologic effect - antianginal, antihypertensive, anti-arrhythmic.

Dosage and Administration

Inside, the food, not liquid, squeezed small amounts of liquid.

Arterial hypertension. Treatment starts at 50 Atenolol 1 mg once a day. To achieve a stable hypotensive effect requires 1-2 weeks of receipt. With the lack of severity of the hypotensive effect, increase the dose to 100 mg in 1 reception. Further increase of the dose is not, as recommended it is not accompanied by increased clinical benefit.

Angina. The initial dose is 50 mg / day. If during the week is not an optimal therapeutic effect, increasing the dose to 100 mg / day.

Elderly patients and patients with impaired renal excretory function requires correction dosing regime. In the presence of renal failure recommended dose correction depending on Cl creatinine. In patients with renal insufficiency at values Cl creatinine greater than 35 mL / min / 1.73 m 2 (normal range is 100-150 ml / min / 1.73 m2), a large accumulation of Atenolol does not occur.

The recommended maximum dose for patients with renal insufficiency:

Cl creatinine, mL / min / 1.73 m2 15-35 less than 15

T1 / 2 of Atenolol, h 16-27 more than 27

The maximum dose 50 mg / day or 100 mg every other day 50 mg a day or one 100 mg every 4 days

To ensure the following are possible use of the dosing Atenolol tablets of 25 mg.

Patients who are on hemodialysis, Atenolol is prescribed for 25 or 50 mg / day immediately after each dialysis, which must be performed in a hospital since there may be a decrease in blood pressure.

In elderly patients, an initial single dose - 25 mg (may be increased under the control of blood pressure, heart rate).

Acute myocardial infarction with stable hemodynamic parameters - 100 mg 1 time per day or 50 mg 2 times a day for 6-9 days or until hospital discharge (under the control of blood pressure, electrocardiogram, blood glucose level). Increasing daily dose of 100 mg are not recommended, since the therapeutic effect is not enhanced, and the likelihood of side effects increases.

Storage conditions of Atenolol Belupo

The temperature is not above 25 ° C.

Keep out of the reach of children.

Shelf life

3 years.

Do not use beyond the expiration date printed on the package.