Instruction for use: Amiridine 20 mg

Active substance: Ipidacrine

ATX Code

N07AA Anticholinesterase drugs

Pharmacological group

M-, n-holinomimetiki, incl. Anticholinesterase agents

The nosological classification (ICD-10)

G12.2 Disease of the motor neuron

Tropical spastic paraparesis, Amyotrophic lateral sclerosis, Bulbar Pallas, Bulbar palsy, Amyotrophic lateral sclerosis, Diseases of motor neurons, Amyotrophic lateral sclerosis, Low-Gehrig's disease, Charcot's disease, Amyotrophic amyotrophic sclerosis, Sclerosis lateral primary, Progressive pseudobulbar palsy, Progressive bulbar palsy, Primary lateral sclerosis

G35-G37 Demyelinating diseases of the central nervous system

G62 Other polyneuropathies

Polyneuritis, Polineuropathy, Inflammation of peripheral nerves

G63.6 Polyneuropathy with other musculoskeletal lesions (M00-M25 +, M40-M96 +)

Polyradiculoneuropathy

G70 Myasthenia gravis and other disorders of the neuromuscular synapse

Myasthenic syndrome, Myasthenic syndromes, Myasthenia gravis, Myasthenic syndrome, Severe myasthenia gravis (Myasthenia gravis)

G73 Lesions of the neuromuscular synapse and muscles in diseases classified elsewhere

Myopathy

K59.8.0 * Atony of the intestine

Atony of the duodenum, Atony of the gastrointestinal tract, Atony of the intestine, Atony of the intestine after operations, Atony of the intestine after childbirth, Atony of the musculature of the gastrointestinal tract, Sluggish peristalsis of the large intestine, Sluggish peristalsis of the colon, Hypotension of the duodenum, Hypotension of the intestine, Hypotension of the large intestine, Hypotonia of the large intestine, Constipation of various etiologies, due to hypotension of the gastrointestinal tract and flaccid peristalsis of the large intestine, Violation of the promotion of intestinal contents, Postoperative atony of the stomach, Postoperative intestinal atony

M79.2 Neurology and neuritis, unspecified

Pain syndrome with neuralgia, Brachialgia, Occipital and intercostal neuralgia, Neuralgia, Neuralgic pain, Neuralgia, Neuralgia of intercostal nerves,Neuralgia of the posterior tibial nerve, Neuritis, Neuritis traumatic, Neuritis, Neurological Pain Syndromes, Neurological contractures with spasms, Acute neuritis, Peripheral neuritis,Post-traumatic neuralgia,Severe pain of a neurogenic nature, Chronic neuritis, Essential neuralgia

R29.8 Other and unspecified symptoms and signs related to neuromuscular and musculoskeletal systems

Paresis, Peripheral paresis, Akinesia

Composition

1 tablet contains amiridine 20 mg; In polymer bottles 50 pcs.

pharmachologic effect

Pharmacological action - anticholinesterase, stimulating neuromuscular transmission.

Indication

Diseases of the peripheral nervous system (neuritis, polyneuritis, polyneuropathy, polyradiculoneuropathy, myasthenia gravis, myasthenic syndrome), demyelinating diseases (complex therapy); Bulbar paralysis and paresis, organic lesions of the central nervous system, accompanied by motor disorders (recovery period); Atony of the intestine.

Contraindications

Hypersensitivity, epilepsy, extrapyramidal and vestibular disorders, stenocardia, bradycardia, bronchial asthma, peptic ulcer (stage of exacerbation), pregnancy, breast-feeding.

pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Side effects

On the part of the digestive tract: hypersalivation, nausea, vomiting, increased peristalsis, diarrhea.

Other: bradycardia, dizziness.

Interaction

Strengthens the sedative effect of agents that depress the central nervous system, including. Alcohol, the effect of other inhibitors of cholinesterase and m-cholinomimetics. Against the background of other cholinergic agents, the risk of a cholinergic crisis increases in patients with myasthenia gravis. Beta-adrenoblockers potentiate bradycardia.

Dosing and Administration

Inside, 10-20 mg 1-3 times a day for 1-2 months (with diseases of the peripheral nervous system and myasthenia gravis). Short-term treatment of myasthenic crises - 20-40 mg 5-6 times a day. Treatment and prevention of intestinal atony - 20 mg 2-3 times a day for 1-2 weeks.

Precautionary measures

With caution appoint with gastric ulcer, thyrotoxicosis, diseases of the cardiovascular system; It is necessary to take into account the ability of the drug to raise the tone of the uterus. Do not use during work drivers of vehicles and people whose profession is associated with increased concentration of attention. For the period of treatment, you must refrain from drinking alcohol.

storage conditions

In a dry place protected from light.

Keep out of the reach of children.

Shelf life

3 years.

Do not use after the expiry date printed on the package.