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Instruction for use: Acenterine

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Dosage form: coated tablets

Active substance: Acidum acetylsalicylicum


N02BA01 Acetylsalicylic acid

Pharmacological groups

NSAID - Salicylic acid derivatives

The nosological classification (ICD-10)

M00-M25 Arthropathy

M30-M36 Systemic involvement of connective tissue: Collagenoses

M45 Ankylosing spondylitis: Ankylosing spondylarthrosis; Marie-Strumpel disease; Ankylosing spondylitis; Ankylosing spondylitis; Pain syndrome in acute inflammatory diseases of the musculoskeletal system; Pain syndrome in chronic inflammatory diseases of the musculoskeletal system; Bechterew's disease; Ankylosing spondylitis; Diseases of the spinal column; Rheumatic spondylitis; Bechterew-Marie-Strumpel disease

M79.0 Rheumatism, unspecified: Degenerative rheumatic disease; Degenerative and rheumatic diseases of the tendons; Degenerative rheumatic diseases; Localized forms of rheumatism of soft tissues; Rheumatism; Rheumatism with a pronounced allergic component; Rheumatism of the articular and extraarticular; Rheumatic attack; Rheumatic complaints; Rheumatic diseases; Rheumatic disease; Rheumatic disease of the spine; Relapses of rheumatism; Articular and extra-articular rheumatism; Articular and muscular rheumatism; Articular rheumatism; Articular syndrome with rheumatism; Chronic rheumatic pain; Chronic articular rheumatism; Rheumatoid diseases; Rheumatic diseases of the intervertebral disc

Structure and Composition

1 tablet with enteric coating contains acetylsalicylic acid 500 mg, in a package of 25 pcs.

Pharmachologic effect

Mode of action - Anti-inflammatory, antipyretic, analgesic.

Indications for Acenterine

Chronic polyarthritis, acute articular rheumatism, ankylosing spondylitis, collagenoses.


Hypersensitivity, gastric and duodenal ulcer, marked decrease in kidney function, diseases accompanied by bleeding, age (up to 10 years).

Pregnancy and breast-feeding

At pregnancy it is contraindicated, at feeding by a breast to consult with the doctor.

Side effects

Irritation of the stomach with burning sensation, ulcers, bleeding from the stomach or intestines, impaired liver function, bleeding from the nose and gums, increased blood loss during menstruation, decreased kidney function with a history of renal blood flow disorder, nephropathy, oliguria, tinnitus, Hearing impairment, allergic reactions (runny nose, face and neck swelling, rash, asthmatic attacks, bronchospasm).


Strengthens the effects of anticoagulants (increased risk of bleeding, especially from the stomach and intestines), sugar-containing drugs, methotrexate; Weakening - diuretic and antihypertensive agents. Alcohol increases the likelihood of developing gastrointestinal side effects.

Dosing and Administration

Inside, not chewing, in the intervals between meals, drinking a little water. The daily dose of 6 table. On 500 mg in 3-4 reception. The dose is selected individually.


Symptoms: headache, dizziness, tinnitus, confusion, sweating, thirst, breathing and blood composition disorders, nausea, vomiting, diarrhea, neurologic disorders (central nervous system stimulation is replaced by progressive depression, with the possibility of transition to coma).

Treatment stationary: includes gastric lavage and reception of activated charcoal.

Precautionary measures

Be wary of patients suffering from asthma, stomach ulcers and duodenal ulcers, bleeding, gastric diseases, decreased kidney and liver function, and the elderly.

Storage conditions of the drug Acenterine

At room temperature.

Keep out of the reach of children.

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