Work of Genes - Genetic noise

Microbiologist says about epigenetics, the mechanism of cell division and fluorescent proteins. What is an epigenetic phenomenon? How does genetic noise? As the noise impact on the further life of a cell? And what is the use in medicine find these studies?

Genetic noise phenomenon occurs, and there is a necessity, for the following reason: when we consider the process of cell division, we always think that after the cell divided, having two identical copies. Indeed, at least in the case of genetic information of DNA have special mechanisms that provide very precise uniform distribution of the total set of genes as a single "daughter" and the other parent cells at division. Thus, if there was any additional mutations during replication of DNA, each of the daughter cells is a clone that is completely identical to the parent cell in terms of genetic information. But in the daughter cell gets not only the DNA - there is also within the cytoplasm of the parent cell.

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Cytoplasm - that's what makes a cage. If the cell - is a pouch with enzymes, i.e. the membrane and within the cytoplasm and the DNA floating in the cytoplasm. It turns out that if you can convey absolutely identical copies of the DNA of each of the daughter cells is exactly the same amount of cytoplasm in the transfer can not be daughter cells: there will always be a small error.

It has medical significance because case role is very important, particularly in antibiotic therapy, because exactly the same as in the situation with a virus and a bacterium, the use of antibiotics will always be situations in which the antibiotic is simply not act on certain cells . Not because they are genetically modified, but now everything is very worried about the emergence of resistant forms of bacteria. Here we are talking about the Darwinian version: bacteria that have altered their genetic structure so that the antibiotic does not work for them at all.

It has medical significance because case role is very important, particularly in antibiotic therapy, because exactly the same as in the situation with a virus and a bacterium, the use of antibiotics will always be situations in which the antibiotic is simply not act on certain cells . Not because they are genetically modified, but now everything is very worried about the emergence of resistant forms of bacteria. Here we are talking about the Darwinian version: bacteria that have altered their genetic structure so that the antibiotic does not work for them at all.