Semax

It's time for another drug from a list of nootropics, and it has a huge name “Met-Glu-Heath-Fe-Pro-Gly-Pro”, and sold in Russia only one brand under the name "Semax". Because we use a trade name, for it is easier (not for advertising).

The History of “Met-Glu-Heath-Fe-Pro-Gly-Pro”

The drug is interesting though that was created in Russia, not so long ago and not too emenates old school piracetam. It all began in the same 60 years in the Netherlands, where local minds took a hormone produced in the body (about it later) and conducted a study on rats. The goal was the most noble - to investigate the effect on the brain, to improve it. Hormones began to study for one simple reason - no synthetic drugs, which would be the most effective and without side effects. So scientists had to swarm "that has long been there." Roughly speaking, they took normal operating hormone which can positively affect the development of the brain, and "sawed", changed it, and everything to find the best relationship between efficiency / safety.

The effects were not revolutionary, but positive. The main difficulty is a short duration, only a few minutes.

In the '70s, the USSR began to put his hand to the development of this hormone. We were able to extend the positive effect of 50 times! And for a greater simplicity - a preparation made as a nose drops and not through the needle as the rats. At the end of 1994 Semax drug was registered. The 97-m included in the first aid kit Emergency Situations Ministry, to assist in the work in extreme conditions. Further, it won several awards in Brussels and Paris. And since 2001, it appeared on the shelves of pharmacies in Russia under the name "Semax nasal drops."

Remember we mentioned about the hormone, so here is - adrenocorticotropic hormone. It is produced in the brain - the pituitary gland. Purpose: regulates the production of other hormones of our adrenal glands, cortisol (the stress hormone, athletes should know), estrogen (a hormone that makes a woman a woman, a man, an excess - a fat man with sagging breasts), progesterone (similar to estrogen, if you do not go into the details ). Adrenocorticotropic hormone contains 39 amino acid residues, residues from the various forms of the protein. This hormone "to saw" that he was to have only 7 residues. Which became, as a whole, Semax.

How does Semax work?

We consider this question from the point of view of its actions "by instillation into the nose to the claimed effects." Because the drug has no analogues and Russia, respectively, with gourmet information sources about it either, in Russia, the only answer to the instructions, "has an original mechanism neurospecific action on the central nervous system" and no details. Well, fix the situation!) Method of analysis analysis let us work semax as 7-amino acid residues!

So, you have dripped on the 3 drops in each nostril. For it is taken for methionyl-glutamyl-histidyl-phenylalanyl. These 4 substances and are working prolyl-glycyl-proline also serve as the first 4th to slow their decomposition, for the extension of their validity. For the last 3 amino acid residues will not be considered - they prolong the action of the first 4.

• 1.A bunch of Met-Glu-Heath-Fe hits the brain. About 60-70% of these residues penetrate through the mucuous membranes of the nose and neuron olfactory tract directly into the brain, and the rest enters the bloodstream. They activate the production of neurotransmitters in the brain such as dopamine (responsible for the motivation and satisfaction), serotonin (general health), acetylcholine (memory, attention, muscular sense), adenosine (acts as sedative). Bundle with the release of dopamine and serotonin is used for the treatment of ADHD (attention deficit syndrome and hyperactivity) and medical depression.
• 2.Activation of NMDA receptors. These receptors are located in the membrane of a neuron, ie to "the nerve cell membrane." They are more responsible for your memory and learning. When you read this, those who have more active NMDA-receptors, will remember more.
• 3.Presumably, it raises the level of BDNF (brain-derived neurotrophic factor). This brain-derived neurotrophic factor and is represented physically as a protein. It is responsible for the formation of new neurons, neural connections and speed development of the brain in general. In addition, this factor contributes to "prolong life" of old neurons and connections. Initially, BDNF is encoded by a gene on chromosome number 11, this means that your level of this protein has laid back by your parents, and you are such a prankster, want to amend the extent of their genetic endowments. But it can happen in a different way, for example when you are in love.

The principle of operation of Semax: traditionally affects neurotransmitters, improves the functioning of the nerve cells via NMDA-receptors, and possibly a little change "system settings" by raising BDNF.

Is Semax effective?

YES, Semax is effective for 100%. In question are only specific, difficult to perceived effects. This drug is also included in the Russian list of essential medicines.

Dosage and side effects

Semaks turned out to be a light-weight adrenocorticotropic hormone, but only with nootropic properties and without hormonal component malfunction because hormones do not expect it. Possible side effects is irritation of nose, with too frequent use. Dosage for "Semax nasal drops 0.1%" of the drug: 3 drops in each nostril in the morning, 2-3 in the afternoon, on the 1st night (can also be 2-3 if a lot of work). The preparation "Semax nasal drops 1%" (Attention !! Do not 0.1%), respectively, 10 times more vigorous, they are dripping with obvious diseases you is pointless.

The course is short only 10-14 days. You will need 2 bottles (0.1%). You can make a break for 1-1.5 months and repeat the course.

What effect you will have?

Increase efficiency, relieve fatigue. But do not assume that you will feel tremors after an exhausting working day. This is not true. Semax make you feel much better than without it, but it does not give you superpowers to continue.

Increasing and improved concentration. It is easier to focus, to delve into any topic, but again, not a panacea, just that you will be the neurotransmitter cocktail that will help you gather and concentrate. Psychoactive effect. Stimulants usually have serious side effects, go hand in hand with them, and the stronger stimulant - the more side effects. In Semax inducing effect can be said is light and refreshing, and therefore no side effects.

When one wait for the effect?

After 3-5 minutes. Yes, this is one of the fastest nootropics. The half-life of the drug - 12-24 hours, this means that it is time to act. Very good, isn’t it?

What one shoul add to Semax?

The best help for Semax is a good healthy diet and light exercise. Indeed, this drug works well in itself, does not need any additional additives.

Summary:

• Semax is a proven working nootropic. It has many international awards. Use Emergency rescue.
• Effects: mild psycho-stimulation, attention, concentration, performance.
• The effect can be expected within 5 minutes, and it will remain at least 12 hours.
• Semax is necessary to drip in a nose. 3 times a day, morning - 3 drops in each nostril, lunch - 3 in each nostril night - 1 minutes each. The course - 10-14 days. Break one and a half months.
• What to do when receiving semax - work, study. Suitable for learning large amounts of information in a short time.