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Retroviruses in Human Evolution

28 Oct 2016

Biologist Dr. Doping talks about the antiviral DNA, the process of accumulation of mutations and the promoters. How are retroviruses? How can they be inherited? When taking place the insertion of retroviruses in the human genome?

Retroviruses are viruses which integrate their DNA into the DNA of the host cell, and from there is carried out the expression of their viral genes read its copy of the genome, which in the form of RNA return in a protein shell and leaves the cell that leads to its death, because cell actually It is broken, and then infect cells and more.

When a virus infects not normal somatic cell, and the one from which then receives reproductive cells, the virus can be inherited as an ordinary mutation, or polymorphism, passed from parent to offspring. In the evolution of the so it happened many times, and now the retroviral DNA is about 6-7% of the human genome, which is equivalent to more than one million acts of incorporation of viruses in the host genome.

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When the virus has been integrated into the host genome, they can be active or inactive, and how they themselves did not lead in their sequences accumulate mutations that inactivated viral genes so that most of the viruses are present there now is in the form of ballast, then It has such sequences, which have the obvious nature of the virus, but can not do anything, because they may not be able to viral genes, and they seem to be completely harmless to the cell, from the point of view of the danger of a classic virus.


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