Active ingredient: Mirtazapine (mirtazapine)
Analogs: Mirzaten, Mirzaten Ku-tab, Mirtazonal, Mirtalan, Noxibel, Esprital
Mirtazipine is a tetracyclic antidepressant, whose action is similar to that of tricyclics. The drug raises the level of norepinephrine and serotonin in the brain, which helps to avoid problems with depression.
According to one of the domestic studies on the effectiveness of mirtazipine, in the early phase of the study (the first 6 weeks of therapy), a clear result was seen in 37 patients versus 13 patients who had either no improvement or little improvement in their condition. It was found that the drug is effective in treating classical depression of various degrees of severity, accompanied by a sense of desperation, despondency, sleep and appetite disorders, pessimistic moods, insolvency ideas and general inhibition. In addition, mirtazipine has performed well in the treatment of anxious depression, where symptoms such as painful discomfort, unreasonable fears, irritation, mental and physical stress, and somatovegetative disorders predominate.
The drug is also great for normalizing sleep on a background of depressive disorders. Mirtazipine quickly manifests its effect, its effect is stable and stable. In addition, the drug is well tolerated, does not cause suicidal thoughts and has virtually no serious side effects.
Indications for use: Depressive disorders of various types, post-traumatic stress disorder.
Contraindications: Hypersensitivity to mirtazipine or certain substances that form part of it, as well as impaired kidney and liver function. In addition, mirtazipine can not be taken concomitantly with MAO inhibitors (after taking an MAO inhibitor it should take at least 2 weeks).
Dosage and administration: The drug is taken orally, swallowing the medicine without chewing. If necessary, wash with liquid.
The minimum daily intake for adults is 15 mg. If necessary, it can be gradually (every few days) increased to obtain an effect. The average effective dose is 15-45 mg / day. In some cases, the dosage can be increased to 60-80 mg / day.
In the elderly, you do not need to reduce the dosage, but you need to be sensitive to the slightest changes in the patient's state of health.
The drug is recommended to be taken within 4-6 months until complete recovery. Then you can gradually give up mirtazipine. As a rule, the drug starts to work during the first month of treatment (starting from the second week). If the effect is not observed, it is necessary to increase the dose, if the improvement does not occur, it is necessary to cancel the drug.
Side effects: Most frequent: drowsiness, increased appetite, dizziness and headaches, unusual dreams, dry mouth and constipation.
Storage conditions: The drug is stored at room temperature (15-30 degrees C).
Terms of selling from the pharmacy: The drug is released on prescription.