Phenazepam - instructions, dosage, side effects, analogs

Antidepressant: Phenazepam (Phenazepamum)

Active ingredient: bromodihydrochlorophenylbenzodiazepine (bromodihydrochlorophenylbenzodiazepini)

Analogs: Diazepam, Elzepam, Oxazepam, Phezanef, Phenzitat, Tranquesipam, Phesipam, Phenorelaxane

Phenazepam is classified as tranquilizer. Removing anxiety, fear and anxiety, this drug has a good soothing effect, accompanied by some hypnotic effect.

The analysis of the drug by many scientists and physicians has led to the fact that phenazepam has by now acquired a solid reputation as a highly effective and at the same time very safe means.

High efficiency of the drug is confirmed by a number of Russian clinical trials. For example, in the treatment of patients with depression, the spectrum of the highest efficacy of phenazepam was identified. It turned out that the drug best helps with anxiety-depressive conditions (in about half of cases the symptomatology disappeared completely, while a third of patients had a significant improvement in the condition), affective-delusional attacks, and also in the syndrome of depersonalization. In general, the positive effect reached about? patients taking phenazepam. At the same time there were no serious side effects, which once again confirms the reputation of phenazepam as an extremely safe drug.

As a means of treating neurotic conditions (with a predominance of anxiety and fear), such as neuroses, schizophrenia and psychosomatic diseases, phenazepam was the most highly effective. In the first days (or even hours) of such treatment, patients demonstrated a sharp decrease in emotional tension, fear, anxiety, and emotions. Simultaneously, normal sleep returned, irritability and aggressiveness decreased. Further administration of the drug only improved the overall picture.

With abstinence, the drug acted in the first hours, relieving mood disorders, tension, anxiety, fear. Accompanying this soporific effect allowed patients to sleep normally, without suffering from nightmarish dreams.

The effect of taking the drug comes in a very short time: positive changes can be felt already in the first days or even hours. And the maximum reduction in symptoms occurs around the 10th day of treatment. Thus, phenazepam is perfectly suitable for a quick and effective fight against powerful emotional experiences, strong feelings of fear, anxiety accompanied by sleep disturbances, and also by many obsessions.

Pharmachologic effect:
Phenazepam has anxiolytic (anti-anxiety), sedative (calming), hypnotic, anticonvulsant and muscle relaxant effect.

Indications for use: Anxiety, irritability, emotional lability, nervous tension and other conditions falling under the category of neurotic, neurotic, psychopathic and psychopathic conditions.

In general, the scope of the use of phenazepam is extensive: insomnia, obsessive conditions, withdrawal syndrome with addiction and alcoholism, epileptic seizures, the etiology of which can be very different, myoclonic and temporal epilepsy, reactive psychoses, senesto-hypochondriacal disorders. The drug is used in schizophrenia as an antipsychotic drug.

In addition, phenazepam is used in neurology for a number of diagnoses (tick, muscle stiffness, hyperkinesia, athetosis). It is also used by anesthetists as a component of introductory anesthesia.

Contraindications: Phenazepam is prohibited for use in people with hypersensitivity to the components of the drug, pregnant and lactating women, as well as minors. In addition, do not use the drug for acute poisoning with drugs, alcohol, and hypnotic drugs. Other contraindications: severe depression, respiratory failure, shock, angle-closure glaucoma, coma, myasthenia gravis.

Dosage and administration: Phenazepam is taken as intramuscularly / intravenously, orally. The choice of method of taking and dosage depends on the type and severity of the problem.

If you need to shortly terminate anxiety, fear, psychomotor agitation (or in autonomic paroxysms or psychotic conditions), the drug is often taken in / m or in / in.

The adult initial dose is 0.5-1 mg, which is equivalent to 0.5-1 ml of 0.1% solution, the average daily dose is 3-5 mg (or 3-5 ml of 0.1% solution). In severe cases, the dosage can be increased up to 7-9 mg (or 7-9 ml of 0.1% solution).

Serial epileptic seizures. In this case, the initial dose (IM or IV) is 0.5 mg (or 0.5 ml 0.1% solution). The average daily dosage is 1-3 mg (or 1-3 ml of a 0.1% solution).

Diseases with increased muscle tone. Intramuscularly, adhering to a dose of 0.5 mg (0.5-1 ml of 0.1% pactworp) 1-2 times a day.

As a premedication preparation. Dosage - iv, slowly injected 3-4 ml of 0.1% solution of the drug.

It should be remembered that the maximum dose should not exceed 10 mg per day. The cancellation must be gradual. If there are stable improvements, it makes sense to switch to oral use of phenazepam.

Usage:
- In cases of sleep disorders, 250-500 micrograms are taken half an hour before going to bed
- With epilepsy - 2-10 mg per day
- When alcohol withdrawal is 2-5 mg per day

Side effects: At the first stage of treatment, drowsiness, dizziness, fatigue, distracted attention, disorientation, unstable gait (in the first place all this concerns elderly patients) may occur. Also, there is a possibility of dry mouth feeling, nausea, heartburn, constipation or diarrhea, anorexia, urinary retention, skin itching, rash (allergic reactions).

Storage conditions: The temperature regime is 15-25 degrees Celsius. Do not allow children to fall into the hands. Store in a dark place.

Conditions for selling from pharmacies: Phenazepam is dispensed on prescription.