On the issue of high altitude Adaptogenes: Mildronate and Olyphen
18 Oct 2016
"What do you mean, you feel bad? Take Ibuprofen tablet and go to the top!" Medical service.
Mountains is a hostile environment for the organism. High mountains are hostile twice. In addition to positive emotions and beautiful selfie for friends, we get a huge dose of ultraviolet radiation, our brain is suffering from hypoxia, which leads eventually to the encephalopathy, the cells do not have enough water for essential metabolic processes. All this accumulates hypothermia, physical and psychological fatigue, excessive load on the heart, liver, kidneys and joints. In general, in the mountains we have mocked own body, already received seven thousand, only 30% oxygen (compared with the partial pressure at sea level), it is not surprising that a few high-altitude expeditions begin to forget the names of those who were there ...
Despite the fact that I am against the ascent with oxygen, I believe that the application of some adaptogens and protectors is justified. If the container is really puts into complete dependence, the drugs have no visible effect and are not doping (at least, those which will be discussed).
So my set is Mildronate + Hypoxen (Olyphen).
Hypoxen is the Russian (Soviet) drug, unknown in the West. All statistics collected in our country. I recommend it originally sports doctor in the clinic. It is very difficult to explain on the fingers of its action, that are interested, read on the Internet. Common sense - Hypoxen improves tissue respiration reduces oxygen consumption, is anti-hypoxic, anti-oxidant agent.
Mildronate (Meldonium) is preparation, that improves metabolism in tissues, especially in heart muscle. As it has antihypoxic properties.
I will not write about the mitochondria, aerobic and anaerobic oxidation of the way, that's all, you can also find and read, especially for people with no medical or biological education process is not interesting, interesting results.
So, about the result. The experiment I started in 2010, with the ascent of Khan and Pick Pobeda. It is clear that without laboratory data useless to argue, but taking Hypoxen, I and co-worker quite easily climbed the Khan with the first exit, without acclimatization. On Pick Pobeda, it was harder, but spending the night on seven thousands were without much suffering.
On all subsequent ascents, I continued to take drugs, since Mildronate 500 mg per day in the races. Adjusted to 4 X 500mg at an altitude of seven thousand, dividing the dose into two doses. I add Hypoxen to four thousand - 500 mg per day, seven thousand - 2000 mg per day. And the record "taking" held on Cho Oyu in the attack the day - in the morning and 2 g 2 g in the process (six hours). I do not know so, but the height of 8100 I was not killed, and even the name of his partner well remember.
This year I was given the case to somehow bring their feelings under the concrete evidence. I had available - the height of 4300, free day, a portable pulse Oximeter (for measurement device saturation), paper, pen, and my body has not yet been jacked up high. Far from claiming to scientific research, to announce the result: quite a positive. The process is as follows: slapping a handful of pills (500h2 Mildronate 250X4 and Hypoxen), trailers Oximeter on the finger, including Pink Floyd for calm I took in a horizontal position, and began to write. In the first hour, nothing happened. After one hour oxygenation (SpO2%) increased from 82 to 86, in two hours to 93% after three hours was 93% through four began to decrease to 90% after five fallen to 88%. Then it was dinner time, and the experiment ended. The next day we climbed the route, oxygen therapy was 79% in the morning, in the evening of 88% (acclimatization + residual effects the morning pills). Then there was no time to measure, we have every day something to climb and accumulated acclimatization. Arrived a few days professional doctor of Medical Service confirmed that this jump in performance for such period of time is impossible without external influence. I would like to repeat the measurement and to him, but he refused because I could not read the instructions, written in Latin. In English we do more or less sane on the Internet is not found.
It should be noted that oxygen therapy - it is an objective indicator of the state, on which you can rely when assessing their state of health and readiness to feats on top.
Do not know, maybe Pink Floyd helped so on, I think all the same .. Hypoxen not insist on anything to anything not call, just a statement of facts.Good luck in the high mountains, not get sick and go home only with good impressions!