Noben (Idebenon) pills - Instructions for Use, Dosage, Side Effects, Reviews

Synonyms: Amizal, Cerestabon, Geniceral, Idecortex, Idesole, Lucebanol, Mnesis, Nemocebral, Pavertrin, Revize, Ulcourona.

Active substance: Idebenone.

ATC - N06BX13 Idebenone

Pharmacological group – Nootropics.

Idebenone (trade names Catena, Raxone, Sovrima, among others) is a drug that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimer's disease and other cognitive defects.

Nosological classification (ICD–10)

F03 Dementia, unspecified;

F06.6 Organic emotionally labile [asthenic] disorder;

F28 Other inorganic psychotic disorders;

F32 Depressive episode;

F48.0 Neurasthenia;

F90.0 disturbance of activity and attention;

G46 Vascular syndromes of brain in cerebrovascular diseases;

H93.1 Tinnitus (subjective);

I67.9 Cerebrovascular disease, unspecified;

R41.3.0 * Reduced memory;

R41.8.0 * Disorders Intellectual mnestic;

R51 Headache;

R53 Malaise and fatigue;

R54 Senility.

Noben (Idebenon) Composition, structure and packing

Yellow capsules, the contents of capsules - granulate containing granules and powder of yellow or orange-yellow with orange and white highlights.

Excipients: lactose, microcrystalline cellulose, potato starch, low molecular weight povidone, magnesium stearate.

Noben (Idebenon) Pharmacological action

Nootropic drug. Improves metabolic processes in the brain by activating the synthesis of glucose and ATP, improving blood flow and tissue oxygenation of the brain contributes to the removal of lactate. Has antioxidant properties, slows lipid peroxidation and thereby prevents neuronal membranes and mitochondria from damage. You can buy Noben.

Also has psychoactive effect and neuroprotective properties. From the first days of taking the drug is anti-astšenic, psychostimulant and antidepressant action. Nootropic action manifests itself, usually after 20–25 days of therapy.

Pharmacokinetics

Absorption

After oral dose idebenone is rapidly absorbed from the gastrointestinal tract, C max in plasma observed after 4 h after administration.

Distribution

Penetrate the BBB in significant quantities and distributed in the tissues of the brain. Not accumulates even after prolonged use.

Breeding

Excreted mainly by the kidneys.

Noben (Idebenon) Dosage

The recommended dose is 30 mg (1 tablet) 2–3 times/day. Duration of treatment - 1.5–2 months depending on the severity of symptoms courses repeated 2–3 times a year.

Capsules taken after meals, the latter method - up to 17 hrs.

Noben (Idebenon) Overdose

Symptoms: increased severity of side effects.

Treatment: gastric lavage, activated charcoal, if necessary, symptomatic therapy.

Noben (Idebenon) Drug Interactions

Prescribed drug interaction Noben not described.

Noben (Idebenon) at Pregnancy and lactation

With careful use of medication during pregnancy and lactation.

Noben (Idebenon) Side effects

CNS: violation of sleep, mental agitation, headache.

Other: allergic reactions, dyspepsia.

Noben (Idebenon) Indications

Psycho-organic syndrome, cerebral blood flow and age involutional changes in the brain;

Cerebroasthenic vascular disorder, traumatic, psychogenic (neurasthenia) and combined etiology, manifested as impaired memory and/or attention, intellectual productivity and reduce overall activity, emotional lability, asthenia, asthenic-depressive and moderately severe depression, headache, dizziness, tinnitus.

Noben (Idebenon) Contraindications

Chronic renal failure;

Hypersensitivity to the drug.

Noben (Idebenon) Cautions

Effects on ability to drive vehicles and management mechanisms

Should not be taken during transport drivers and others whose profession requires quick mental and motor responses.

Noben (Idebenon) Reviews

Clair, 21 years, "Noben" - A very good stimulant for the brain
Advantages:
Effective medicine
Five years ago, my life has really changed dramatically. All in a pile - marriage, a new job, and admission to the university. At first, everything as it happened on the emotions and everything is easy to give, but two years later came the terrible feeling of fatigue. Dizziness, memory loss, and even some sort of melancholy in bulk. I went to the reception to the therapist, it is recommended to consult a neurologist. It turned chronic fatigue syndrome. And I had not guessed? Work and Study plus plus household chores. I think I overestimated its capabilities). Treatment was surprisingly not difficult. Propyl Nobena course and felt much better. Vertigo stopped, the blues receded and memory, by the way, has improved markedly. So if someone like symptoms, and go to the doctor once, you know, there is such a drug Noben. Its properties and descriptions, I will not describe here can search in google and read. I can only say that it is suitable for all age categories, it improves brain function, feeding it with oxygen. I'm his classmates introduced himself and his mother. I wish you all good luck and do not be depressed (you know, the blues have a cure!).

Olga, 27 years, "Noben" - I became more active, fatigue disappeared, became much better to remember.
Advantages:
Gone fatigue, better start to remember something, respond faster

After my neurologist complaints residual peculiar shape of the object when it is offset to the left, he had some tests and sent me for an MRI of the brain. Well, after description he appointed me Mexidol, Tenoten and Noben:
All these 3 drugs at the same time I applied, but still convinced that each act on a specific problem: fatigue, forgetfulness, stress, depression, and other things that I have found a doctor after a fairly long dialogue before prescribing medications.

I think that helped me Noben improve memory, I became more actively something to do as well as much faster to respond to these problems (there was a time when I began to do some things a little more slowly than before, and this impacted on an incomprehensible fatigue).
In common with many primary and secondary issues I handled, and what is required to this drug Noben.