Neuroleptics, Antipsychotics. Part 7

It remains to tell more about the two neuroleptic - of new, atypical. Perhaps, then, a separate post, is worth mentioning about the forms of release neuroleptics, which allows not to take them every day in the tablets and make a shot, say, once every two weeks, and then once a month - but we'll see whether or not it Togo. And yet - get acquainted.

Quetiapine. Seroquel, Ketilept, Kventiax, Nantarid, Lacvel - so much more the name of each company is trying to call by its own. The main point of its application is delusions and paranoid syndrome. In this respect, Quetiapine may be somewhat inferior to Olanzapine - because he gets a little more courteous and considerate with regard bulldozer crazy designs, but he has a couple of features, due to which, in some cases it is preferred to use Quetiapine.

Yes, it is just as Olanzapine, is quite rare, and much weaker than the classical antipsychotics is neuroleptic syndrome. Yes, it is less and less, than risperidone causes lethargy and drowsiness - although at times may well prove to be. But there is another important point: Quetiapine, in contrast to olanzapine and risperidone, much less can cause a rise in blood prolactin levels and much less likely to cause weight gain - in other words, on it less fattening. You can buy Phenazepam.

And one more feature: it is better than the actual delusional or paranoid, Quetiapine effect on depressive-delusional and depressive-paranoid symptoms. Sometimes, though (rare, but cases have been) can "knock out" the person on the opposite - manic or hypomanic phase, and this should be taken into account. But in general, this feature allows you to use it in the treatment of not only schizophrenia, but also bipolar disorder (TIR, as soon as it was called), especially in the depressive phase, when in fact joins the second depression delusions of guilt, self-humiliation, worthlessness, and other worm-like. Just in this case (when the depressive-delusional syndrome developed with MIS), quetiapine is prescribed more than one, and in combination with an antidepressant. In principle it is possible to continue later, when the exacerbation has passed, but the planned transition to a manic phase - but will have to combine quetiapine is not with antidepressants, mood stabilizers and on (about them the story is yet to come). And one more feature that is celebrated and quetiapine, and a number of other antipsychotic drugs - is its ability to reduce the depth of the emotional and volitional defect or decrease in schizophrenics. It is very important, it should be noted feature.

Aripiprazole. Abilify, Zylaxera, Amdoal. Perhaps it is not so much effect on hallucinations as Solian and risperidone, and not so zealously opposes delirium as olanzapine and Seroquel. Maybe. But it gives the side effects much smaller than other atypical (and even more - classical) antipsychotics. That is, much less when his reception there neuroleptic syndrome, much less can expect complications of the heart, by the endocrine system (ie, prolactin, for example, it is much less likely increases and diabetes rarely causes), it rarely affects the weight gain. And so aripiprazole pretty good use as a medicine for long-term maintenance treatment - at the same schizophrenia or bipolar disorder, for example. And also it with less apprehension can be used, if developed psychosis in adolescents aged 13 years. Or in patients with diabetes mellitus. Or a patient with cardiac problems. In principle in some cases it can also be used for acute treatment of established, not only for its prevention.