Neuroleptics, Antipsychotics. Part 4

And a few more doses, before I start to talk about the modern atypical. Two of them, Fluanxol and Clopixol, appeared much later than all the classics of the series, and were, so to speak, a transition stage to Atypical antipsychotics - not counting Azaleptinum and Eglonil. Chlorprothixene is well known for a long time, but in itself is quite good in the work and deserves a mention.

But first a few words about the pursuit Eglonile. The fact that it applies not only in psychiatric practice - love him to appoint gastroenterologists. Why? Because Eglonil acts not only on the nerve centers of the brain, but also in the plexus, which regulate the stomach, intestines and bile-deducing ways - for example, on per-gastric and sunny. And quite a beneficial effect - in any case effectively enough to eliminate a malfunction of the autopilot.

Chlorprothixenum. According to the chemical formula reminiscent of chlorpromazine (yes, the same three hexagonal ring with one eye and one tail), but in him in the assembly of a chemical designer changed the nitrogen atom to the carbon atom - purely to see what happens. The result was a neuroleptic, chlorpromazine which acts softer, less likely to cause neuroleptic syndrome, has a similar to chlorpromazine (but again, softer) soothing effect. But the most valuable - he is aiming to act on hallucinations. Weaker than haloperidol, but due to its (relatively) soft and combining it with a calming effect goes well for older people with hallucinations in delirium tremens, as well as organic hallucinosis, when haloperidol too exerts its side effects, or at all paradoxical effect - strengthening of hallucinations in the build-up dose. Sometimes (and small, literally micro-dozes) used in hysterical and hypochondriacal neuroses.

Fluanxol. Flupentixol. On the spectrum of action similar to triftazine - that is intended to overwhelm the delusional system, to reason with the paranoid and otherwise ward off evil thoughts. On the hallucinations he acts much weaker. Besides the treatment of delusional and paranoid states Fluanxol gives a good effect in the treatment of obsessive-compulsive disorder - with obsessive thoughts, actions, phobias and rituals (I do not mean the maniacal desire someone ritually kill, although there Fluanxol could partly help) . Almost does not have an inhibitory effect, and hypnotic. cause neuroleptic syndrome may be, but much less often and less than triftazine and especially haloperidol.

Clopixol . It is, to put it and the international non-proprietary - Zuclopenthixol. On the spectrum of action similar to haloperidol: as actively suppresses the voices off vision, cuts ties with the cosmos and deactivates pentagram call otherworldly entities. Oh, and by the same psychic abilities to successfully heal. In some cases more effective than haloperidol. However, neuroleptic syndrome may cause - a little less and a little weaker than haloperidol, but noticeable.

Here, perhaps, and all. In the following article it will be possible to move to the new atypical antipsychotics. Stayed in a corner droperidol, but about him I did not write, as in psychiatry, he almost never used: it anymore so resuscitators anesthesiologists benefit when doing neuro-leptanalgezis.