Active ingredient: Phenelzine (phenelzine)
Analogs: Nardil – Phenelzine, Phenibut, Mexidol
Nardil is a potent inhibitor of monoamine oxidase (MAO). Depression is most often associated with an imbalance of certain chemical compounds in the brain. The concentration of these compounds (monoamines) in the central nervous system during depression is significantly reduced. Monoamines are cleaved with the help of a special substance monoamine oxidase (MAO). Phenelzine interferes with the work of MAO, and therefore, contributes to an increase in the number of active monoamines in the brain. Thus, the imbalance is normalized, and the depression recedes. Despite the fact that "Nardil" is not the most modern antidepressant, many scientific studies show that it has a profound potential in the treatment of social phobia. Phenelzine has an effect on serotonin and dopamine, as well as aminobutyric acid, which, as a rule, can solve all problems related to social anxiety.
The drug was recognized effective in the treatment of patients with depression, clinically characterized as neurotic and atypical (not endogenous). Such patients often have a whole complex of manifestations, including anxiety, the symptoms of depression itself (feelings of sadness, fear, anxiety), as well as hypochondriacal states and various phobias. In addition, there is evidence that it is somewhat less effective in controlling severe forms of endogenous depression.
Thus, a study in Toronto found that about 25% of patients with severe depression, accompanied by chronic mental disorders, achieve complete recovery; in 32% the improvement was sufficient to permit discharge, and a noticeable improvement was noted in 12% of patients.
"Nardil" very often helps those patients who have not experienced improvements during treatment with other antidepressants. A noticeable therapeutic effect occurs after 2-4 weeks of taking the drug.
Indications for use: Depressive disorders
- children's age till 16 years;
- violations of the liver (including in history);
- heart failure;
- diseases of the blood vessels inside / around the brain (cerebrovascular diseases);
- adrenal gland tumor;
- manic-depressive syndrome in the manic phase;
- allergy to the components of the drug.
Side effects: The following effects are the result of an individual reaction to the drug, but this does not mean that they will manifest in everyone who starts taking phenelzine. The most frequent of them: drowsiness, orthostatic hypotension, dizziness, insomnia, weakness and fatigue, dry mouth, nausea, vomiting, constipation, headache, blurred vision, increased sweating and appetite, arrhythmia.
Terms of selling from the pharmacy: Without a prescription.