Gepatoprotektors in bodybuilding

Gepatoprotektors are a group of various medicines to which protective influence on a liver is attributed. In bodybuilding gepatoprotektors found the application, in connection with hepatoxicity of many anabolic steroids. Hepatoxicity of steroids is caused by metilny or ethyl group in alfa-17 line items.

It is proved that not all gepatoprotektors have protective influence in case of the use of steroids. The choice is limited to the following list (as decrease in efficiency):

• Ademetionin (Heptral) - besides high recovery activity, has anti-depressive effect that does it by the preferable choice for post course therapy.
• Medicines on the basis of a thistle - substance is active: silimatrin (Karsil, Legalon)
• Phospholipids (Essentsiale) (there is information that in connection with viscosity of bile on a course, it is categorically contraindicated to inclusion in course time)
• Alpha lipoic acid
• Arginine
• Ornithine

The most effective combinations of gepatoprotektors:

• Karsil + Essentsiale + Alpha lipoic acid
• Essentsiale + Alpha lipoic acid + arginine
• Alpha lipoic acid + Geptral + arginine

Regime of acceptance and dose

Begin acceptance on the 2nd week of a steroid cycle and continue to accept 3 more weeks after the termination of a cycle, it is desirable to accept a complex of gepatoprotektor (see above).

Recommended doses

• Karsil - on 0:07 g 2 - 3 times a day
• Essentsiale - on 1-2 capsules 2-3 times a day during food, with a small amount of water.
• Alpha lipoic acid of 100 - 200 mg a day
• Arginin - 1 g, 2 times a day
• Ademetionin - 800-1600 mg/days between meals to swallow, without chewing, it is desirable in the first half of day

Efficiency of gepatoprotektors

It is necessary to emphasize that any of gepatoprotektors aren’t provided in Pharmacopoeias of the countries of North America, Europe, Australia and New Zealand and isn't included in Clinical Recommendations. On the English-speaking Internet information on gepatoprotektors very poor as in the West they aren't widespread. It is connected with the fact that gepatoprotektors have very weak evidential base, and in case of serious poisonings efficiency not really high. However during acceptance of steroids the complex of gepatoprotektors can reduce considerably risk of damage of a liver therefore doesn’t neglect this opportunity at all, and surely include them in PCT.