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Dynamic Heterogeneity of bio-membrane

01 Nov 2016

Biophysicist tells about pharmacological targets, the computer model of the membrane and its properties. Why the interest in the study of membrane proteins? What difficulties arise in the study of biological membrane? And what are the properties of the membrane?

For many years it was thought that the main component of cell membranes are proteins. This remains valid. Membrane proteins - some of the most interesting and promising pharmacological targets. According to one estimate over 60%, on the other - over 70% of all drugs present on the market today operate exactly at the target in membranes, basically on proteins: on receptor systems, channels and so on. Interest in membrane proteins and it is due.

It was found that the membrane - is not just the inert matrix, which is necessary in order that the proteins in it are located and operated. Membrane - a very active and dynamic environment, which significantly affects the operation are there proteins. It is not homogeneous in its properties. Rafts or rafts - it's formation in cell membranes, which by their characteristics are different from the rest of the lipid bilayer.

That’s why Peptide Cerluten is suitable for prevention of diabetes and improve metabolism, and Peptide (Cytomax) Suprefort is for prevention of diseases of the pancreas and the restoration of its functions.

What this mosaic nature of the biological membrane may need a cage? In our computational experiments, we showed that the mosaic allows the cell membrane to react quickly to external influences. With the cell membrane and interact with proteins and peptides, and many other compounds.


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