FIFA urgently checked Russian football team "Rostov" for Meldonium.

On Thursday 12 May, FIFA held a sudden massive test of the players of the Russian football club "Rostov" in connection with the allegations of the use of Meldonium. On the doping control taken away just 11 football players of Rostov team.

- It was an unannounced drug test, which I initiated, based on the rumors that the players of "Rostov" football team take Meldonium, - said the head of the Medical Department FIFA Jiri Dvorak. 

"Rostov FC" will not lose medals. But it can lose three points.

Yesterday, just 11 players "Rostov FC" was tested for meldonium. Today we tried to figure out why it happened. And what that means.

Mutko: Meldonium in "Rostov" - fictional things

Yesterday the "Rostov FC" made a cool "comeback" in Khimki, making 0: 1 with "Dynamo" to 3: 1. Berdyev's team once again delighted and play, and character. It would seem, for the "Rostov FC" a cloudless and positive day. But it was not. Overexhausted players insistently invited to doping control. Eleven players at once. It's clear that no one in the team was not happy.

And the public was very surprised.

Of course, the players, "Rostov FC" immediately began to tell that they can find no trace of dope. Best of all the club's position expressed Timofei Kalachev: "I have not got time for doping control. And in the Russian league and the national football team. But most - three people, usually two. And then 11 ... amazing! What does it mean? No answer. This is a test or distrust? It is necessary to understand.

Well, we would pass a doping test! Control will reveal no problem. No one uses no pills or illegal drugs in our team. Let check 11 ... We have nothing to fear. On the contrary, if a drug test does not reveal, we are clean in front of everyone. "

Christian Noboa responded emotionally. And it is understandable: "This is unreal! We, all 11 players, sit and wait for the doping control. It never has been. Always called only two people. And then 11 ... How so? Well, let's wait. "

Dmitry Poloz quite reasonably remarked: "Somehow, in the last year, when we were fighting for survival, none of the representatives of FIFA inspections did not come to us. And in general, not a question of - let them come to us with checks at least after every game. The main thing is that we won. "

Coach Vitaly Kafanov affected to the financial side of the issue. Even if we wanted to buy meldonium, we could not. "Yes, we have no money for even basic medicines! What to say about Meldonium (Mildronate). I do not believe that the guys used illegal drugs ".

Of course, the word “Meldonium” quickly appeared in news articles. Well, where without Mildronats in modern Russia. The first to speak the same Kalachev: "Do you think, digging under the" growth "? Let's see, the main thing that did not find any meldonium or that there are now searching for? I think everything will be fine. We play so well only on a normal diet. "

The saddest thing is that this topic of Mildronate is not over. Because fears are confirmed – they are really looking for Meldonium. This is not speculation, but the official FIFA position. Here is a quote the head of the medical department, Jiri Dvorak: "It was an unannounced drug test, which I initiated on the basis of rumors that the players of "Rostov FC" take Meldonium.

FIFA Team of specialists from different countries came to the stadium before the match, with all the necessary documents. I have to give a big compliment to the service of the security and management of FC "Rostov" - they have a full understanding to the visit of the FIFA officers".

On this statement, it has been needed a serious answer. No representatives of the "Rostov FC" and leadership of Russian football. That is Vitaly Mutko: "Meldonium in "Rostov"- it's absolutely far-fetched things. Russia is preparing for the World Cup, and the International Federation of Football begins to take control of football in Russia and in terms of doping control. Thus, the Russian team was subjected to doping controls in France. I understand it, the schedule control leaders of the Russian Championship has been made. "

This, of course, a very "realistic" version - check "on schedule" 11 players of the team. Amazing schedule, I must say.

Andreev: "The history of doping in the" Rostov FC"- is the intrigue of CSKA or Zenith.”

However, a word from the professionals. The former head of the Russian Anti-Doping Agency Nikolai Durmanov focuses on the 2018 World Cup in our country.

"Most likely, in the samples of the players," Rostov FC " one will find no Meldonium, because football - it's still fairly prosperous sport. Unusually in this story is that the entire team checked. This is due to the World Cup - 2018. Some people now have to trample on football, something to discover - is part of far-designed program. In football, the sample is usually taken from two people.

I doubt that in "Rostov FC" will find doping. But if the team comes across a hypothetical, in such cases, the following guidelines apply: if a drug is found in one person, the results do not match will be void and the team is not penalized. But on the next test will take samples not two players, but four. At least it was until recently, but maybe the rules have changed. And if they catch more than two people, the proceedings are sometimes the result is annulled, and the team sanctions. But depending on what kind of doping which circumstances. In some cases, even for one person and sanctions may be applied to the club.

By the way, there are conspiracy theorists. For example, coach Sergei Andreev, who knows very well what it is like - to work in Rostov.

"The whole story Doping in Rostov - this is not the machinations of FIFA. For me there is no doubt that this is the work of some of the other two clubs which claim the championship. Crept in doubt - as if not both. Previously there was no such precedent. On doping test taken one or two players, but to 11 ... And it happens when "Rostov" is fighting for the gold medal. Clearly, this is going to feed those in power. Can the players, "Rostov" take Mildronate? I do not know about that.

The fact that "Rostov" in recent games will take six points, no doubt. But if CSKA pick up - the question. "Zenith" even gaining. Even under the condition that the St. Petersburg group gain the maximum points at 100 per cent result, "growth", they still do not become champions.

I do not be surprised if someone will test positive for Meldonium. And not because the players have taken illegal drugs, but because everything can pour. After all, people come from FIFA. People who stirred up the hive of the very power structures. And then think out already. But times have already begun, they will go to the end. "

It remains to understand one thing - if you suddenly doping and the truth will find that it is waiting for "Rostov"? The FIFA Anti-Doping Regulations reads as follows: If more than two members of the team have been convicted of violating anti-doping rules, the committee should impose appropriate sanctions on the club in addition to the sanctions imposed on individual players. Simply put, the result of the

match, which was held after the doping test, the FIFA decision be annulled. That is, the "Rostov", in theory, could void the three points for a win in the game with the "Dynamo". But not all the points earned in the Premier League.

Accordingly, "Rostov" takes a high place in the table anyway. But the fight for the gold and silver, even it can complicate seriously. However, hard to believe that someone in the team took really dope. Especially - meldonium. 

There are new details in Sharapova’s Meldonium gate

There are new details in a notorious case of tennis player Maria Sharapova related to Mildronate

It became known, when exactly it held a hearing in court. The servants of Themis will find out details of the case on May 18 in London. Recall that in early spring athlete released information about a finding Meldonium in analysis.

Mildronate is banned by the World Anti-Doping Agency (WADA) from January 1, 2016. Sharapova was unable to take part in competitions, starting from 12 March. Experts say that the maximum penalty for an athlete to use this material - suspension from games for four years. Disqualification shall enter into force immediately after Sharapova dismissal from employment. All the parties may appeal the decision within three weeks from the date of its notification.

As reported, "URA-Inform", recently the President of the Russian Federation asked how he manages to stay in good physical shape. To which Putin replied. "No Meldonium. Absolutely."

Maria Yuryevna Sharapova is a Russian professional tennis player, who is ranked world No. 9 by theWomen's Tennis Association (WTA). A United States resident since 1994, Sharapova has competed on the WTA tour since 2001. She has been ranked world No. 1 in singles by the WTA on five separate occasions, for a total of 21 weeks. She is one of ten women, and the only Russian, to hold the career Grand Slam. She is also an Olympic medalist, having earned silver for Russia in women's singles at the 2012 Summer Olympics in London.

In March 2016, Sharapova revealed she had failed a drug test at the 2016 Australian Open, admitting to testing positive for meldonium, a substance banned by the World Anti-Doping Agency (WADA) at the start of 2016, and was provisionally suspended from playing tennis by the International Tennis Federation (ITF)

Doctor: "Rostov" stopped taking Meldonium in October, but traces may remain

Medical staff of "Rostov FC" stopped giving players Meldonium injections in October last year, immediately after receiving the recommendations of the World Anti-Doping Agency (WADA), however, taken the players after the match with the Moscow "Dynamo" doping tests can show the presence of traces of the drug, said the agency "P -Sports " doctor of “Rostov FC" Vladimir Khokhlov.

On Thursday, 11 players "Rostov", which came out in the match 28-round championship of Russia against Moscow "Dynamo" ( Rostov win with the score 3: 1) in the starting lineup, passed a drug test after the game. FIFA later announced that the mass of players test was associated with previously appeared in the media information about the buy of mildronate 500mg drug by the club that with January 1, 2016 is included in the list of banned WADA.

"In principle, up to 31 December any athlete could use Meldonium, based on the logic - said Khokhlov on the phone. - After the Mildronate was added to the Prohibited List as from 1 January. We received a letter from WADA in October, since immediately stopped taking the Mildronate injections. Before it really used Mildronate as meldonium 500mg has been recommended by leading experts of Sports Medicine. "

Khokhlov said he did not know whether there is any traces of Meldonium in the doping tests of players "Rostov". "FIFA Doping officers just told us that will notify about the results of the test. Neither the timing nor the method of notification did not specify. Who knows, there may be some traces of Mildronate in samples of our players. Some may be, because it all depends on the characteristics of the organism from metabolic processes. But again, we stopped taking the Meldonium (Mildronate 500mg) immediately after receiving the recommendations of WADA. "

Russian MMA fighter Islam Mahachev convicted in application of Mildronate.

Russian mixed style fighter (MMA) 24-year-old Islam Mahachev suspected of using Meldonium, whcih prohibited in sports with the January 1, 2016. The incident was reported by the organization "Absolute Fighting Championship» (Ultimate Fighting Championship, UFC).

Mahachev temporarily suspended from competition in the tournament UFC (Ultimate Fighting Championship) to ascertain all the circumstances. He canceled his fight with Drew Dober, who was supposed to take place on Saturday, April 16, in Tampa (Florida, USA).

In January 2016 World Anti-Doping Agency (VADA) add Meldonium (Mildronats) to the list of banned substances. In March, sparked doping scandal - Meldonium was detected in the blood of more than a hundred athletes around the world. Among them were representatives of Russia - Maria Sharapova, skater Ekaterina Bobrova, short-track Yelistratov Semen and Ekaterina Konstantinova, swimmer Yuliya Efimova, and many others.

Mildronate in sports

Mildronate in capsules

Mildronate (meldonium, kardionat) – is a preparation that improves metabolism and energy supply of tissues prescription. The product was created in the 70-ies of XX century in the Institute of Organic Synthesis of the Latvian SSR, engaged in the development by Professor Ivar Kalvins. Initially the compound was patented as a means to control plant growth and stimulation of growth of animals and poultry.

WADA is considering mildronats as a metabolism modulator, similar to insulin. A study published in December 2015 in the journal Drug Testing and Analysis, argues that meldonium increases of athletes, endurance, improves recovery after the performance, protects against stress and increases the functional activity of the central nervous system. Thus these effects have been confirmed mainly only Latvian scientists.

On January 1, 2016 meldonium has been added to S4 class (hormones and modulators of metabolism) Prohibited List and is prohibited for use in the competition and contest season.

Effects of Meldonium inBodybuilding

• Mildronate prevents accumulation of activated cells in unoxidized form fatty acids.
• In conditions of ischemia meldonium restores the balance of oxygen delivery and consumption processes in the cells, to prevent violations of transport ATP.
• THP activates glycolysis, which proceeds without the use of supplemental oxygen.
• MET – 88 improves muscle power.
• Mildronats increases the effectiveness of training
• Quaterine reduces fatigue.
• Mildronate protects the heart and improves myocardial contractility.

Note Bene:

Mildronate (meldonium) has cardioprotective, anti-anginal, anti-hypoxic, angioproteguoe action. Is structural synthetic analogue of gamma-butyrobetaine - carnitine precursor. It inhibits the enzyme y-butyrobetaine hydroxylase carnitine reduces the synthesis and transport of long chain fatty acids across cell membranes and prevents the accumulation of cells in the activated forms of non-oxidized fatty acids (including acylcarnitine blocking delivery of ATP to cell organelles). Improves metabolic processes. When ischemia prevents violation of transport and ATP activates glycolysis. As a result of reducing the synthesis of carnitine in the cell increases the content of y-butyrobetaine, has vasodilating action. Against the background of heart failure improves myocardial contractility, increases exercise tolerance. Increases cellular and humoral immunity. It increases efficiency, reduces the symptoms of mental and physical stress, enhances stamina. If ingestion is well absorbed from the gastrointestinal tract. Bioavailability - about 78%. Maximum plasma concentration is achieved in 1-2 hours half-life -. 3-6 hours Side effects -. Dyspepsia, agitation, tachycardia, hypotension, pruritus. The average dose for adults at intake - 250 mg 2-4 times a day.

Meldonium: artificial respiration

How does meldonium work, and why he was banned, causing a scandal that has engulfed the whole world of sports?

September 16, 2015 the list of drugs banned by the World Anti-Doping Agency (WADA), added meldonium, which was introduced to a group of hormones and metabolic modulators (S4), along with insulin. On January 1, 2016 as the drug is prohibited during training and competitions, and the beginning of March was marked by a string of scandals associated with his discovery in the blood of athletes - mostly, alas, Russian.

As a result of this scandal temporarily disqualified Maria Sharapova and volleyball player Alexander Markin, biathlete Eduard Latypov and swimmer Yulia Efimova. "Meldoniumgate" has touched dozens of athletes from the different countries, according to the WADA, illegal drug was found in the blood of more than 60 athletes, and this number is growing rapidly. Well, we will try to understand the history and pharmacology of the disputed preparation.

The Breath of Heart

n the early 1970s, Anatoly Eremeev, Ivars Kalvins with colleagues at the Institute of Organic Chemistry and partners from the Moscow Medical Institute, worked to create the drug to help patients with cardiovascular disease. The fact that the angina and other conditions pre-infarction oxygen supply of cardiac muscle dangerously impaired. The objective was to facilitate the work of the myocardium during hypoxia.

Recall that the energy for all the processes in our cells - including those for reducing heart muscle cells - supply of ATP molecules. They produce special cellular organelles - the mitochondria, which are therefore often referred to as "power plants" of the cell. And for the very synthesis of ATP energy supplies oxidation of glucose and fatty acids - the processes of cellular respiration.

The process of oxidation of fatty acids can bring a lot more energy than the "burning" of glucose, but it requires much more time and oxygen. Thus it inhibits the use of glucose, leading to the accumulation of lactic acid. To make better use of oxygen under conditions of shortage, can block the entry of fatty acids into the mitochondria, causing them to switch to an emergency glucose uptake.

This can affect the mechanism of transport of fatty acids across the mitochondrial membrane into them. A key part of this mechanism is the amino acid L-carnitine: it binds with a fatty acid, "tagging" it to migrate through the membrane. Carnitine is synthesized in the body from gamma-butyrobetaine, and synthetic analogue is 3- (2,2,2-trimethylhydrazinium) propionate dihydrate or simply meldonium. Competing with gamma-butyrobetaine, he "mistakenly" bound enzyme, which should make it into a carnitine, and block its work. The transfer of fatty acids across the mitochondrial membrane is suppressed.

For War and For Sport

In the method for the synthesis of meldonium Kalvins Ivars and his colleagues received a copyright certificate of the USSR in 1979, and an international patent - in 1984. During these years, the drug was approved for use by the Soviet Ministry of Health and called "Mildronate" was registered as a means to improve performance during rehabilitation, psychological and physical overload.

Not surprisingly, almost simultaneously with the medical meldonium interested in military and athletes. According to Ivars Kalvins, the drug was tested in combat in Afghanistan. But after the collapse of the Soviet Union the right to a patent in 1992 was Ivars Kalvins who sold them the Latvian company of Grindeks, which is not the first year engaged in the production meldonium.

For more than 30 years of application of the drug has become really popular among professional athletes. Gradually they began to accumulate data that use of meldonium increases stamina, improves recovery after stress, protects against stress and activates the function of the central nervous system. However, Ivars Kalvins considers it rather a forced protection for an athlete, running at the limit of strength.

In an interview Kalvins said: "Doping - a substance that increases the excess of something in the human body. Over and above the norm. And so you can not use it safely. Be sure to leave an undesirable doping mark on their health. This mildronate, in my opinion, should be given to all athletes to ensure that they are not spoiled your health, because their task - to perform at maximum capacity. " According to the inventor of the drug, its inclusion in the list of banned doping WADA was made solely on the basis of statistical data on the impact of its application on the performance of athletes. Properly controlled studies have been conducted.

Either way, the decision is made, and WADA officials said they did not intend to cancel it. Here it is worth remembering that meldonium indeed more widespread in the countries of the former Soviet Union, while in the West applies its analog trimetazidine. He was included in the register of substances prohibited by the WADA, back in 2014.

Meldonium (Mildronate) by Grindex amazingly increases the strength and endurance during sports workout

The last days who even slightly follows the news, heard of such a preparation as meldonium. It is prohibited to receive athletes, as recognized by doping with the US submission. Let's see what all the same it is a medicine and whether it really works wonders with the human body.

Should I use meldonium An ordinary man, if he is not an athlete and is not experiencing congestion, eat right and maintain a healthy lifestyle, the drug will be useless. Since it is not BAD, which enrich the body with vitamins. In the first place - it is a drug, which supports a person in good shape, feeds the heart, and other organs, exhausted after a strenuous work or exercise.

How meldonium works If the product enters into the human body, begins a uniform distribution of the incoming oxygen by the cells. In parallel with this, meldonium prevent the possible spread of toxic substances and their degradation products in the body. Thus, the cells in the human body is protected from the adverse effects.

Mildonate, it is essentially a cardioprotective agent, which is necessary for the following diseases:- Lack of oxygen and heart failure. Meldonium can effectively regulate all energy resources in the body. In addition, it stimulates the cellular metabolism. During the period of taking this drug, the human heart is reduced by several times less, but these cuts are much more intense. As a result, it slowly wears down.
- After a stroke patient take meldonium. It normalizes blood circulation in the brain, stimulates cell renewal. What is very important for a speedy recovery.
- People who have had a myocardial infarction, meldonium help repay necrotic center. Thereby reducing the risk of another attack, the patient is recovering faster.

It's not all diseases that are stopped with the help of this drug. As can be seen, this drug is specialized exclusively on the work of the heart and brain. As if the body's brain and heart work properly and no shortage of necessary substances, the person feels good, he is full of energy and ready to move on.

Reviews of Doctors According to doctors meldonium assumes no danger to human life. On the contrary, it helps to keep the body stable, even during heavy physical and mental overload. This drug was loved by doctors as in Soviet times, and so far it is actively prescribed to people who are experiencing stress, over-voltage, as well as those who suffer from various heart diseases. News that meldonium recognized doping doctors introduced our country in shock, as no scientific basis for such a decision no. This product deserves only positive reviews, and it's not just words, but the truth, supported by excellent results. Even ordinary people, not related to sports leave only positive feedback about Maldon, this can be seen in the huge number of sites.

If I say to myself - I drink with those pills to improve training results (do boxing).

I just realized that meldonium found in every cell of the body, and its use improves the supply of oxygen to the cells.

What is the effect of the mildronate I felt on myself?
1. When the exercise, after a week of reception as described in the manual scheme forces accurately added.
2. Pronounced imunomodeliruyuschy effect.
3. The positive impact on the nervous system.

These capsules are small, their application is quite comfortable.

And the best thing is not to hurt, to be an active and cheerful.

Health for all of us!