Choline alfoscerate - Active Substances. Instruction and Application, Dosage

Name: Choline alfoscerate

The Latin name of the substance Choline alfoscerate

Cholini alfosceras (genus. Cholini alfosceratis)

chemical nameCholine hydroxide, (R) -2,3-dihydro-ksipropil-phosphate (inner salt)

Formula - C8H20NO6P

Therapeutic agents of Choline alfoscerate:

Nootropic agent

The nosological classification (ICD-10)F00 Dementia in Alzheimer's disease (G30 +)
F03Unspecified Dementia
G10 Huntington's disease
G46 Vascular syndromes of brain in cerebrovascular diseases
G93.4 Encephalopathy, unspecified
I63 Cerebral infarction
I69 The effects of cerebrovascular disease
Violation orientation unspecified R41.0
R41.3.0 * Reduced memory
S06 Intracranial injury

CAS code - 28319-77-9

Pharmacology

Mode of action - neuroprotection.

Excited cholinergic receptors, mainly central (having cholinomimetic effect). The body is split into choline and glycerophosphate. The substrate provides the synthesis of acetylcholine and phosphatidylcholine neuronal membranes. It stimulates the cholinergic neurotransmission, improves the plasticity of neuronal membranes and function of receptors activates cerebral blood flow, stimulates the metabolism of the central nervous system and reticular formation. Improves mood, improves alertness, concentration, memorization and the ability to reproduce the received information, to optimize cognitive and behavioral reactions, eliminates emotional instability, apathy. In the acute period of craniocerebral traumas helps to normalize blood flow and brain bioelectrical activity on the affected side, promotes regression of neurological symptoms. You can buy online Gliatilin.

Absorption of ingestion - 88%; easily penetrates through the BBB, predominantly accumulates in the brain (the brain concentration reaches 45% of the level in the blood), lung and liver; Light 85% excreted as carbon dioxide, the remainder (15%) excreted by the kidneys and in the intestine.

No effect on the reproductive cycle is not teratogenic and mutagenic effect.

Application of the substance Choline alfoscerate

Traumatic brain injury (acute phase) with mainly stem lesion level, chronic cerebrovascular insufficiency (encephalopathy), dementia (Alzheimer's type, senile, mixed forms), ischemic stroke (the recovery period), Huntington's chorea, functional CNS disorders, impaired memory, confusion, disorientation, decrease in motivation, initiative and concentration, senile pseudo-melancholy.

Contraindications

Hypersensitivity, pregnancy, breast-feeding.

Pregnancy and breast-feeding
At the time of treatment should stop breastfeeding.

Side effects of substance Choline alfoscerate

Nausea, allergic reactions.

Dosing and Administration of Choline alfoscerate Substances

Inside, before meals, 400 mg 3 times a day, the course of 3-6 months. In acute conditions: w / o or w / w (slowly) 1 g / day.

Trading names of drugs with working substance Choline alfoscerate

Trade Name

Gleatser
Gliatilin
Glycerylphosphorylcholine hydrate
Deletion
Lipids GPC 85
NooprinŽ
Nooholin Rompharm
Vos GPC 85
Choline alfoscerat
Choline alfoscerat 25% solution
Choline alfoscerat hydrate
Holitilin
Cerepro
Cereton