Cell death and its use in medicine

Biologist Dr. Doping tells about active and passive processes of cell death, necrosis, and ways of dealing with cancer. How is apoptosis? What diseases can lead to cell death? Why in different cells and tissues of different forms of death work?

The process of cell death can be active or passive. Passive process - when the injured cells are not able to repair damage to their own and must be somehow eliminated as many tissues within the body. Active process - this is when the cell realizes that it has fulfilled its function, and that should be allowed to operate other cells. A typical example of such an active process - embryogenesis or differentiation.

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The population of cells in any tissue is governed by three processes. The first - a cell division, when their number increases; second - differentiation when the number of cells increases or decreases depending on the tissue; and third - this cell death. These processes are responsible for the proper functioning of tissues and organs. If we take the average weight of a person (70 kg) - every day we lose about 1 kg of our weight. This is a normal physiological process. The most actively dying cells - this intestinal epithelial cells over a lifetime they change almost 4,000 times. If the cells do not die, for 70 years of life, we have produced 30 km of the intestine.

The dead cells in the body should be eaten either macrophages or neighboring cells. This is very important because if there is no inflammation, which is dangerous for the tissues and body. Very few cells simply die, many of them commit suicide, it is in certain and necessary conditions. There are two physiological state. The first - when a lot of cells are killed, leading to loss of homeostasis. Second - this is when there is no cell death, or it defective, and then the amount of accumulated cells. Both situations are abnormal, and there are plenty of diseases associated with cell death. Depending on how much or little of cells killed in the same organ may cause such situation exactly the opposite of the disease.