Bremelanotide

Bremelanotide (the laboratory code of PT-141) - the peptide developed by the Palatin Technologies company is Melanotan's 2 analog, but is used mainly for strengthening of an erection and a libido. Bremelanotide is a metabolite of melanotan 2 at which is absent amide S-terminal. Peptide passes clinical tests as means for treatment of erectile dysfunction and frustration of a sexual passion. In addition medicine causes sharp strengthening of suntan (due to melanin development stimulation by melanotsitama cages).

Bremelanotide can be applied both to men, and to women. In difference from Viagra and similar means, it not only influences vessels of genitals, but also strengthens a sexual passion (desire).

Preliminary results of researches confirmed its efficiency, however testing were stopped in connection with development of side effects: rise in arterial pressure at some examinees. Peptide was entered in the form of solution.

In August, 2009 Palatin Technologies announced positive results (side effects disappeared in case of a hypodermic way of introduction). Final results will be received at the end of 2012.

In parallel Palatin Technologies study similar substance under the code of PL-6983 which exerts smaller impact on arterial pressure.

Application

The effect after an injection develops within two hours and reaches the peak on the third - the fourth hour. The general duration of action reaches 8 - 10 hours.

Bremelanotide is issued in bottles, in the form of the dry lyophilized powder. Storage conditions: in a dry form at a temperature of 0-8 C degrees. The expiration date makes 2 years. In the dissolved type of PT-141 it is necessary to store also in the refrigerator, but the term of his storage is reduced to 1-3 months.

Method of application: Injections are carried out by the insulin syringe hypodermically or less often intramuscularly (the five-vat syringe with a needle of 40 mm). In the form of spray is not recommended to apply as there can be side effects connected with rise in arterial pressure (according to the carried-out tests). The optimum single dose of PT-141 makes: 0.5mg - 1.5mg (rolled into one 10 mg of active agent most often contain). You can try Nootropil.

Preparation and storage of solution: It is necessary to cool a bottle to room temperature, to enter the necessary volume of water for injections (which has to flow down on a bottle wall) and to stir the rotating movements (not to shake). The prepared solution remains stable for 14-20 days in the refrigerator without freezing.

Yu. Bombela writes that it is better to dissolve this peptide by means of physical solution, then the received solution can be stored about one month in a deep freeze. Proceeding from features of application of PT-141, solution is recommended to gather in syringes and after it to freeze. To defreeze before the use on one syringe.