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Biotredin (Pyridoxine+Threonine) tablets - Instructions for Use, Dosage, Side Effects, Reviews

24 Jan 2017

Active substance: Pyridoxine + Threonine.

ATC - A11JC vitamins in combination with other drugs

Pharmacological group - Vitamin means in combination.

Generic Name: pyridoxine (vitamin B6)

Brand Name: Vitamin B6, Vitelle Nestrex, Pyridoxal 5'-Phosphate

What is Pyridoxine?

Pyridoxine is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body.

Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

What is Threonine?

Threonine (abbreviated as Thr or T) encoded by the codons ACU, ACC, ACA, and ACG is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+

3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and an alcohol containing side chain, classifying it as a polar, uncharged (at physiological pH) amino acid. It is essential in humans, meaning the body cannot synthesize it, and must be ingested in our diet.

ATC - A11JC vitamins in combination with other drugs

Pharmacological groups - B vitamins + other drugs [Vitamin means in combination].

Nosological classification (ICD–10)

F10.1 Harmful use of alcohol;

F10.2 alcohol dependence syndrome;

F10.3 abstinence;

F34.8 Other persistent mood disorders [affective];

F48 Other neurotic disorders;

F60.3 Emotionally unstable personality disorder;

F90.0 disturbance of activity and attention;

R41.8.0 Disorders of intellectual-mental;

R45.4 Irritability and anger.

Composition, structure and packing

Sublingual tablets white or white with a yellowish tint plano-cylindrical shape with beveled.

1 tab.

L-threonine - 100 mg

pyridoxine - 5 mg

Excipients: low molecular weight polyvinylpyrrolidone (Povidone), citric acid monohydrate, magnesium stearate.

Pharmacological action

Pharmacological action - metabolic, neuroprotective, anti-alcohol, anti-withdrawal symptoms.

Biotredin is a regulator of tissue metabolism, improves mental performance, has a healing effect for alcohol withdrawal state, reduces the craving for alcohol.

L-threonine in the presence of pyridoxine (vitamin B6) decomposes into amino acids glycine and acetaldehyde, which stimulate inhibitory processes and simultaneously the oxidation-reduction reactions and respiratory processes of synthesis of adenosine triphosphate (ATP) in the cells, whereby the drug is able to:

Reduce the emotional stress;

To improve the short-term and long-term memory;

To improve mental performance;

Improve and normalize the levels of endogenous acetaldehyde and thereby reduce the effect of alcohol withdrawal syndrome and alcohol craving.

Action of Biotredin manifested in 10–20 minutes after taking under the tongue.

Pharmacokinetics

L-threonine, and pyridoxine completely metabolized to the final products. Their accumulation in the organism occurs.

Biotredin Indications

Prescribed to children, adolescents and adults with a decrease in mental performance and concentration.

The drug is prescribed for persons who abuse alcohol, suffering from chronic alcoholism when updating the craving for alcohol, coupled with affective (irritability, depressed mood, inner discomfort), sensory (feeling of hunger) and ideational (thoughts about alcohol) disorders with alcohol withdrawal syndrome, and to maintain remission.

Biotredin Contraindications

Drunkenness, simultaneous reception of drugs which depress the central nervous system (anxiolytics, antipsychotics (neuroleptics), antidepressants, etc..), Increased sensitivity to vitamin B6.

Pregnancy and lactation

Studies have not been conducted. Not recommended for use during pregnancy and lactation.

Alcohol abuse and alcoholism, the drug may be used during pregnancy and while breastfeeding.

Biotredin Dosage and administration

The drug is administered in tablet under the tongue or as a powder after crushing tablets; as a means of improving attention, mental performance: children, adolescents and adults: 1 tablet 2–3 times a day for 3–10 days. If necessary, repeat 3–4 times or more per year.

Patients with chronic alcoholism and alcohol misuse prescribed 1–3 tablets to receive 2–3 times a day for 4–5 days. If necessary, repeat 5–10 times a year.

In the treatment of alcohol withdrawal syndrome administered on the first day 1–4 tablets 3–4 times a day (daily dose of 3–16 tablets), on the second day and then at 1–2 to receive 2–3 tablets twice a day (daily dose 3 –6 tablets) for 21–28 days.

Course duration can be shortened to 10–14 days.

Biotredin’s greatest effect is achieved when it is combined with the drug Glycine (100 mg tablet). Glycine to take under the tongue for 10–15 minutes before of Biotredin.

In remission for detecting latent craving for alcohol take 2–3 tablets on an empty stomach of Biotredin. The emergence within 10–20 minutes of light dizziness, calming effect, facial flushing, sweating indicates the presence of “hidden traction.” In these cases it is recommended 5–10 day course of Biotredin 1–2 tablets 2–3 times a day along with 100 mg of Glycine under the tongue for 10–15 minutes before of Biotredin.

Biotredin Side effects

Dizziness, sweating, allergic reactions in case of intolerance vitamin B6.

Biotredin Overdose

Overdose cases have been identified.

Biotredin Interaction with other drugs

Incompatible with antipsychotic drugs, antidepressants, anxiolytics, barbiturates. Reduces the effect of antipsychotic drugs (neuroleptics), antidepressants, barbiturates and other drugs which depress the central nervous system.

Biotredin Reviews

Acquired Biotredin to improve their psycho-emotional state, mainly brain activity. Now show "Dancing" is a means of vengeance PR, and I thought: why not? I have to say that the manufacturer Biotredina the same as that of glycine. No need to be a rocket scientist to see the original design of their products.

Convenient packaging, white tablets, classic reception for this group of drugs - under the tongue. The flat design makes it easy to take the vehicle to work or on the road. What can I say? "Tablets for memory" actually causes the brain to move quickly begin to "cut one's way" in the work. Given my biorhythmic belonging to the family of "owls", I immediately felt a positive change. However, to get the real effect is necessary, so to speak, to revise their preferences. After studying the instructions and packaging Biotredina, I was very intrigued by the information that means more and is a drug for the treatment of alcoholism. Contra "drunkenness" generated interest, and I was not too lazy to call their hotline. I was told that the agent is generally better not to combine with alcohol, otherwise no effect from it will not. And this applies even to the evening of alcohol that night was to be absorbed and naturally leave the body. For the "alcoholics", I am told, and does Dummy (if you continue to drink alcohol). But it is worth, the assurances of the consultant, the man to miss at least one day without alcohol and try Biotredin as thrust will begin to decline, exerting a beneficial effect on the body. Fortunately, I could not even if you want to test this promise: alcohol dependence do not suffer.

Indications: decreased performance, attention and memory; persons with chronic alcohol dependence, in the period of withdrawal symptoms (withdrawal), in the presence of craving for alcohol, to maintain remission.
Contraindications: Alcohol intoxication, concomitant use with CNS depressants (anxiolytics (anti-anxiety), antidepressants, antipsychotics, and so on.).
The drug contains vitamin B6 and L-threonine. Apply it in order to improve performance, attention and memory. The tablets used for this purpose under the language- one tablet three times a day. The taste is similar to glycine, a little sweet. As this drug is used for the treatment of alcohol dependence and craving for alcohol (in combination therapy). The package contains 30 tablets. Course admission is 10 days. Course may be repeated if necessary up to 5 times a year. Overall, after taking the drug, I have not noticed any changes in memory, thinking, attention. Nootropics are able to help people with diseases of the CNS. Calming effect Biotredin I just had not noticed. This is the weakest of all drug nootropics that I have tried. With it you can check whether you have a craving for alcohol In order to do this on an empty stomach to put 2 tablets under the tongue. If there are unpleasant subjective sensation, this indicates a positive result. The drug reduces the effect of drugs which depress the central nervous system, as well as alcohol. Not recommended for lactating and pregnant women. Before use, you must consult your doctor. In general, I think that the lack of effect on my memory, thinking, attention due to the fact that the drug is intended for people who really have a problem with that. And I wanted to test the effect on my body of this drug. Perhaps this individual response. Be healthy!

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