Betaserc - instructions for use, how to apply in the cervical osteochondrosis, analogs, reviews

Betaserc is a synthetic analogue of histamine, which acts on the H1 and H3 receptors of the inner ear and brain vestibular nuclei. Due to the activation of histamine receptors drug improves blood flow and lymph circulation in the inner ear structures and normalizes the vestibular apparatus. Therefore Betaserc used to remove vestibular vertigo, tinnitus, and to improve the hearing if it is reduced. In addition, the drug is used in Meniere's disease and vertigo, as well as for the relief of dizziness, headaches, tinnitus, nausea and vomiting caused by various diseases and syndromes (eg, vertebrobasilar insufficiency, encephalopathy after injury, atherosclerosis of brain vessels, vestibular neuritis, labyrinthitis, vertigo after neurosurgical operations).

The composition and the form of Betaserc
Currently Betaserc medicament manufactured in a single dosage form - a tablet for oral administration. As the active ingredient tablets contain Betaserc betahistine (betahistine dihydrochloride) in three doses - 8 mg, 16 mg and 24 mg. That is, one tablet may contain Betaserc 8 mg, 16 mg or 24 mg of active substance.

In common parlance to refer Betaserc in various dosages using short names "Betaserc 8", "Betaserc 16" and " Betaserc 24" where the drug is added to the name of a figure that reflects the content of the active substance in the tablet.
Tablets Betaserc all three dosages as auxiliary components comprise the same material as follows: colloidal silica; Mannitol; Microcrystalline cellulose; Citric acid monohydrate; Talc.

Betaserc tablets 8 mg released in packs of 30, 60 and 180 units, Betaserc 16 mg - 30, 60 and 105 units, and Betaserc 24 mg - 20, 25, 30, 40, 50, 60, 100 and 120 units.
Betaserc Tablets 8 mg are white and have a circular shape with flat sides and beveled edges. On one side of the tablet is engraved "256" on the other of the inverted triangle icon and the letter "S" under each other.
Betaserc Tablets 16 mg and 24 mg are white and have a round biconvex shape with bevelled edges and scored on one side. At the 16 mg tablets on both sides there is a risk engraved "267" on the other side of the tablet icons - inverted triangle and "the S", located under each other. At the 24 mg tablets on both sides there is a risk engraved "289" on the other side of the tablet icons - inverted triangle and "the S", located under each other.

Cervical Betaserc
Since Betaserc used to eliminate dizziness, headaches, nausea and instability provoked by cervical osteochondrosis, it is often some types of medication that are used with this purpose is called "cervical" Betaserc. But due to the fact that in osteochondrosis can use the drug in different doses - and 8 mg and 16 mg and 24 mg, then any kind may be "neck" Betaserc. That is, it should be remembered that Betaserc any variety can be a "neck", and its name is similar to the use of the drug in osteochondrosis.

Therapeutic action of Betaserc

The main pharmacological effect Betaserc - the improvement of blood microcirculation and lymph flow in the structures of the inner ear and vestibular nuclei of the brain, provides the impact on histamine receptors H1 and H3 types. Influenced Betaserc in the brain tissue of the inner ear, and increased the number of produced and released by a biologically active substance histamine, which provides expansion of capillaries and improve blood microcirculation and lymph flow in the brain and cochlear area (inner ear tissue).
In addition, normalization of Betahistine accelerates the restoration of the vestibular apparatus neurectomy after surgery (removal of the nerve), facilitating the process of the brain's level of compensation. The period of recovery of vestibular function in humans after neurectomy when applying Betaserc proceeds much faster.
Also Betaserc inhibits arousal in the vestibular nuclei - brain regions that regulate the work of the vestibular apparatus. Through this inhibition Betaserc effective for the treatment of various diseases of the vestibular apparatus (eg, vertigo, Meniere's disease, labyrinthitis, etc.).
Clinically Betaserc quickly relieves attacks of vestibular vertigo, reduces the intensity of the noise in the ears and hearing improves, if it has been reduced. In addition, regular use of the drug reduces the frequency and intensity of attacks of dizziness, headaches and tinnitus. Improving the condition appear immediately after taking the first tablets Betaserc, but lasting effect is achieved only after 2 weeks of use of the drug. The best results are seen with chronic administration Betaserc (more than 4 weeks). Moreover, after a long course of therapy effect of the medication remains for several months, and even more enhanced.

Indications for Betaserc
Betaserc indicated for use in the following conditions or diseases: Treatment and prevention of vestibular vertigo (vertigo) caused by various diseases and conditions, such as vertebrobasilar insufficiency, traumatic encephalopathy, atherosclerosis of brain vessels, vestibular neuritis, labyrinthitis, vertigo after neurosurgical operations; Disease and Meniere's syndrome; Various syndromes manifested by dizziness, headache, tinnitus, hearing impairment, nausea and vomiting.

Betaserc - instructions for use

Betaserc 8, Betaserc 16 and Betaserc 24 - application of the general rules
The tablets should be taken orally with meals, swallowing them whole and washed down with a small amount of still water (just half a glass). 8 mg tablets should be swallowed whole without breaking, not bite and grinding in other ways. A tablet dosages of 16 mg and 24 mg could be divided in half, if necessary. For this tablet is placed on a flat surface and pressed against the notch up her thumb on one side so that it broke in half.
In various diseases and conditions Betaserc take under identical dosages which are 24 - 48 mg per day. The total daily dose is divided into three times and take in about equal intervals. Embodiments Betaserc receiving different dosages are shown in table.

Betaserc 8mg - Take 1 - 2 tablets 3 times a day;

Betaserc 16mg - Take 1/2 - 1 tablet 3 times a day;

Betaserc 24 mg - Take 1 tablet 2 times a day.

The dosage selected individually depending on the reaction of the human body for medical treatment, since a minimum. That is, the first person to recommend or take 1 tablet Betaserc 8 mg or 1/2 tablet Betaserc 16 mg 3 times a day, which is 24 mg per day (lowest dose). If this dose is ineffective, it is possible to increase the total daily dose of 8 mg per day, bringing it to 32 mg, and take the medication according to the following scheme:

• In the morning take 2 tablets Betaserc 8 mg or 1 tablet Betaserc 16 mg;
• At lunchtime and in the evening take 1 tablet Betaserc 8 mg, or 1/2 tablet Betaserc 16 mg.

Accordingly, if the dosage of 32 mg per day is effective enough, it is increased by 8 mg, leading to 40 mg per day. This medication should be taken as follows:

• In the morning and in the afternoon take 2 tablets Betaserc 8 mg or 1 tablet Betaserc 16 mg;
• In the evening take 1 tablet Betaserc 8 mg, or 1/2 tablet Betaserc 16 mg.

And in case of failure, and this dosage, it increased another 8 mg, leading to a maximum - 48 mg per day, which can take any of the following manner:

• Take either 2 tablets Betaserc 8 mg or 1 tablet Betaserc 16 mg three times a day (morning, afternoon and evening);
• Take 1 tablet Betaserc 24 mg twice a day.

Basically, in a single day can be taken Betaserc and 8 mg and 16 mg and 24 mg, while respecting the dosage. That is, in the morning, you can take one tablet 16 mg Betaserc for dinner - 2 tablets Betaserc 8 mg, and in the evening - half a tablet of Betaserc 24 mg. Duration of treatment Betaserc varied, ranging from 2 weeks to several months and it is determined by the speed of improvement of the human condition.
Long-term use of the drug it is possible and justified, because Betaserc not appear to have any adverse effects on various organs and tissues of the body, and is not addictive.
The dosage of the drug is not necessary to reduce the application in the elderly (over 65 years), as well as those suffering from hepatic or renal insufficiency. Special studies on these issues are not made, but the long experience of the drug allowed to come to these conclusions about the possibility to apply Betaserc in conventional dosage in the elderly and those suffering from renal or hepatic insufficiency.

Pregnancy and breastfeeding
There are no reliable and accurate data on the safety Betaserc to the fetus, and pregnancy is not. Moreover, unknown even to the potential risks to the fetus, and pregnancy. It should therefore refrain from the use of the drug during pregnancy and breastfeeding period.
However, if there is an urgent need to use Betaserc in pregnant women, when the potential benefits outweigh the possible risks of all, it can be done, but in minimal doses and for the shortest possible period of time.
In addition, women who took Betaserc and did not know about her pregnancy, should not necessarily have an abortion, because the probability of the birth of a normal, healthy child is high. In such a situation, do not miss the screening ultrasound (12, 22 weeks of pregnancy), during which detect abnormalities in fetal development.
If US data is due to an irregularity is found, then the pregnancy is normal and the drug did not have any negative effects on the fetus. If necessary Betaserc for woman nursing an infant feeding, the baby should be converted to artificial milk formula, because it is not known whether and how much the drug in human milk is released.

Special Instructions for Betaserc
Do not use the drug for the treatment of children under the age of 18, since there are no reliable data on its safety and efficacy for this category of people.
Caution should be used Betaserc people suffering from asthma or stomach ulcers and / or duodenal ulcers at the current time, or have had these diseases in the past. In bronchial asthma during the entire period of application Betaserc person should be under medical supervision.

Overdose of Betaserc
Currently, a few cases of overdosage have been recorded that occur when taking more than 640 mg (corresponding to 80 tablets Betaserc 8, 40 and 15 tablets Betaserc more than 26 tablets Betaserc 24) of the drug. Symptoms of overdose include the following symptoms: Nausea; Vomiting; Headache; Redness of the skin; Dizziness; Tachycardia; Low blood pressure (hypotension); bronchospasm; Convulsions.
Cramps, bronchospasm, tachycardia and hypotension were reported only in cases of intentional overdose when Betaserc taken simultaneously with other medications. However, even in these cases, the person managed to save and return to normal life after the poisoning.
Treatment of overdoses is followed by gastric lavage technique sorbent (e.g. activated carbon, POLYSORB, Polyphepanum, Filtrum etc.). After that, being symptomatic therapy if necessary, aimed at maintaining the normal functioning of vital organs.

Interaction Betaserc with other drugs
Specific interaction studies with other medications Betaserc in terms of clinical application have been conducted. However, based on the long experience of the drug, doctors and scientists concluded that Betaserc no incompatibility with any drugs. This means that Betaserc may be used in combination with any other drug that requires the person. But it should be remembered that the simultaneous reception Betaserc with antihistamines (eg, Suprastin, Diazolin, Claritin, Fenistil, Aerius, Telfast, Zyrtec, Parlazin etc.) reduces the effectiveness of the latter.
Furthermore, experimental studies have revealed that Betaserc efficiency may decrease when used with drugs from the group of MAO inhibitors (e.g., selegiline etc.). Therefore, theoretically, be careful when applying Betaserc with MAO inhibitors.

Betaserc at osteochondrosis
In diseases of the cervical spine, such as low back pain, spondylosis and other, often have painful symptoms of dizziness, double vision, instability in the standing position, etc. Usually, this manifests symptoms when making movements in the cervical region, and it is caused by compression of the arteries that bring blood to the brain structures. Due to the compression of the artery occurs insufficiency of cerebral blood flow, which is manifested dizziness, double vision, unstable standing, unsteadiness of gait, ataxia, nausea or vomiting.
At the sharp turns of the head with osteochondrosis may appear in the so-called "push aside", in which a person feels the instability and may even fall. In such a situation, a person embraces a sense of disorientation in space, he can not clearly understand the true state of his body, and sometimes it is joined by nausea with vomiting. And true dizziness thus missing, but the person perceives its unstable position, disorientation in space in conjunction with nausea and accordingly it describes the status of the doctor as dizziness.
In the treatment of the above disorders (dizziness, unsteadiness, nausea, etc.), often observed in osteochondrosis, the most effective means is Betaserc or its synonyms. The drug improves blood flow to the brain, relieves irritation and excessive activity of neurons in the vestibular center and thereby eliminates dizziness, double vision, unstable posture, as well as nausea and vomiting caused by osteochondrosis of the cervical spine.
Betaserc can be used as for the occasional relief of acute attacks of vertigo, and courses for the prevention of such conditions. For the relief of acute, rapidly emerged dizziness caused by osteochondrosis, it is necessary to take 2 - 3 tablets Betaserc 16 (32 - 48 mg). The effect is very fast, dizziness passes, and the condition is normalized.
In addition, Betaserc indicated for the long course taking in order to reduce the frequency and severity of attacks of dizziness caused by osteochondrosis of the cervical spine. In this case, taking Betaserc 16 mg 3 times a day, or 24 mg 2 times a day for 2 - 3 months. The drug does not have a sedative effect, does not affect the functioning of other organs and systems, and is therefore well tolerated and is perfect for long-term use.

Side effects of Betaserc
Tablets Betaserc different dosages may provoke the development of the following side effects: Nausea; Vomiting; Dyspepsia (belching, flatulence, bloating, constipation, diarrhea, etc.); Abdominal pain in the stomach and intestines; The feeling of heaviness in the stomach; Headache; Allergic reactions (angioedema, urticaria, rash, pruritus, anaphylactic reaction).
Abdominal pain and dyspepsia are transient, ie, quickly go through some time after the beginning of the drug. If these side effects have not been within 2 weeks of Betaserc it is necessary to reduce the dosage or exclusively take tablets with food.

Contraindications for Betaserc
Tablets Betaserc all three doses are contraindicated for use in the presence of a person of the following diseases or conditions: Individual hypersensitivity, intolerance or allergic reactions to any component of the drug; pheochromocytoma; The period of acute gastric ulcer or duodenal ulcer; During pregnancy or breastfeeding.
Precautions should use the drug in the presence of a person has asthma or transferred in the past gastric ulcer or duodenal ulcer. These diseases are not absolute contraindications, but if any condition of the person should be kept under close supervision by a doctor during the entire period of application Betaserc.

Betaserc - analogues
Any drug in the pharmaceutical market are drugs, analogs, which are divided into two varieties - are synonymous and, in fact, analogs. Synonyms are drugs that contain the same active ingredients. That is, in the case of Betaserc, it will be synonymous medicines containing as active ingredient betahistine. The analogs are drugs that have the most similar spectrum of therapeutic activity, but contain different active ingredients. With reference to Betaserc this means that its analogs are agents which improve the cerebral circulation.

So synonymous Betaserc are the following drugs: Asniton tablets; Betaver tablets; Betahistine tablets; Betatsentrin tablets; Vazoserk tablets; Vertran tablets; Vestibo tablets; Vestikap capsule; Denoize tablets; Micrograins tablets and drops for oral administration; Tagista tablets.
By Betaserc analogs include the following drugs: stugeron tablets; Cinnarizine tablets.

Reviews about Betaserc
The vast majority of reviews Betaserc (over 90%) are positive, due to the high efficiency of the preparation and rapid improvement. Betaserc effectively eliminates dizziness, ringing in the ears and head, as well as feeling "storm" from side to side in people suffering from diseases of the brain vessels. The review indicated that the painful symptoms pass quickly, in just a few days after the start of Betaserc, but for stable and long-term effects need to drink the drug for 1 - 3 months. After a course of the drug people have commented that they cease to be afraid of falling in the street or at home, and, accordingly, can safely go to work, to shops, to stay in the apartment without supervision, etc.
Also in the review notes that Betaserc effectively relieves vertigo, tinnitus, and unsteady gait with hypertension or cerebrovascular disorders (including post-stroke). The feedback regarding the use of the drug for diseases of the data indicates that overall health is normalized, it disappears constant sense of danger associated with the possibility of falling, etc.
Many positive responses observed Betaserc disadvantages to which people carry high costs and pain in the stomach, arising during treatment. However, these shortcomings are well tolerated outs generally good preparation.
Negative reviews about Betaserc literally unit and they are due, as a rule, the absence of expected therapeutic effect or development of allergic reactions. The negative review as the basis for this impression of the preparation indicated the lack of effect on people who counted. That is, people hoped that Betaserc completely and permanently eliminate the dizziness and the drug only reduces the severity and frequency of this unpleasant condition.

Betaserc in osteochondrosis - reviews
Most of the comments on the application of Betaserc osteochondrosis positive, due to the high efficiency of the drug in the elimination of vertigo and tinnitus. As in osteochondrosis can often squeezes blood vessels feeding the brain, then, respectively, in this case the person will have trouble dizziness, headaches, tinnitus, etc. Betaserc improves cerebral blood circulation and rapidly eliminates these symptoms, normalizing the status and well-being.
The review indicated that as a symptomatic drug Betaserc simply magnificent, as fine relieves dizziness and tinnitus, but, unfortunately, does not treat the cause of these symptoms. Therefore, in order to effect Betaserc osteochondrosis maintained for a long time, you must also use drugs or carry out procedures aimed at improving the state of the spinal tissues.
Negative feedback on the application of Betaserc osteochondrosis virtually none. Much more positive responses, which indicate deficiencies in the existing drug in the opinion of people.