Antipsychotics, Neuroleptics. Part 2

It is time to continue to acquaint you with the contents of the magic suitcase psychiatrists. The last time we spoke about haloperidol, and triftazin, Tisercinum. Now - all of those neuroleptics, we are widely used for many years, but which seems to have passed into history: in any case, in Russia they have not been re-registered in the last ten or fifteen years have disappeared from the arsenal. Nevertheless, it is worth remembering about them.

Majeptil. Another name thioproperazine. It is very powerful antipsychotic. However, its action is quite selective. Therefore, in the first place in psychiatry majeptil used to treat patients with catatonic schizophrenia (regardless of what is currently dominated - catatonic stupor or catatonic excitation), as well as patients with hebephrenic schizophrenia. In some cases - adjusting the dosage to a horse, that is, making the so-called shock therapy majeptilic. Pretty harsh measure, but enough to see the patient in catatonic excitement - and you will realize that it is justified. And above all, in its effect. Neuroleptic majeptil syndrome is more frequent and severe than haloperidol.

Trisedyl. The international non-proprietary name - trifluperidol. And the chemical formula, and of close to haloperidol. But stronger. And significantly. It used in cases where haloperidol give in to "Voice" or "visions". Why not replace it entirely? Because of powerful neuroleptic syndrome, which causes trisedyl more willing and more than haloperidol. Furthermore hallucinations (and to a lesser extent, delusions) trisedyl used to treat the same catatonic schizophrenia, and also to quickly break the manic state or by TIR at schizo-affective disorder.

IMAP. Fluspirilenum. Intra-Muscle antipsychotic. Redeptin .A little more impact on the hallucinations, delirium slightly weaker, but most importantly - it does not slow down, but rather activates. And actions not only on the productive (the same hallucinations and delusions), but what is important - on the negative symptoms. By reducing the depth of the emotional-volitional decline, struggling with apathy (but that apathy within the defect of personality, not to be confused with the usual in our understanding of apathy!) And this property flyushpirilena used to the patient after the hospital, as they say, brought back to life. By the same active life, with the restoration of the lost social skills and relationships. With convenient - it relates to sustained release formulations (ie, renewable) period of validity, and it is usually done once a week (it was issued in the form of injections). Neuroleptic Syndrome is roughly the same frequency and power as haloperidol, so it is usually administered along with the correctors (Cyclodolum).

Orap. Pimozide. It pretty good acts on the paranoid syndrome, so frequently and successfully used for its treatment, when the patient has already been discharged from hospital, but any symptoms, though weakened, still exist (and paranoia - a thing hard), or is (and it is most often available) the likelihood that these symptoms will return soon. What it was comfortable - it's the fact that giving a pill Orap could be once a day. Pimozide acted for a long time. In the morning I took - all day free. Neuroleptic Syndrome causes about as often, and somewhat stronger than haloperidol.

Frenolon. The international non-proprietary name - metofenazate. Neuroleptic which is essentially used for the treatment of psychosis itself, because its action on delusions, hallucinations, agitation or powerful mania was quite weak. But it worked well, if it was necessary to cope with the lethargy and apathy in the same schizophrenic psychosis is acute. Or to cope with anxiety and fear in a patient with long-standing neurosis as long reception tranquilizers guaranteed to get you to get used to it. Neuroleptic syndrome is rare and much weaker than haloperidol.