Acetylcholine, the IQ 180

Good all day! What do we know about the brain and about the intellectual abilities? Frankly, a little, but what we know for sure that there is a neurotransmitter that helps to improve cognitive abilities. If Darwin's theory is correct, then it is with every generation will be produced in larger quantities, if a person does not degrade. The interest in that its level can be increased now, moreover, with acetylcholine can "play" that he developed the first one then the other property of the brain. He will not make you happier, more energetic or calm, but it will be more reasonable man than he was before, he will accelerate the learning process, ceteris paribus.

Acetylcholine is one of the first discovered neurotransmitters, it happened in the first half of the 20th century.

What produces acetylcholine?

Acetylcholine is responsible for intellectual ability, as well as for neuromuscular communication, not only biceps, triceps, and the autonomic nervous system, ie for bodies muscles.

Large dosages of acetylcholine "slow down" the body, "small" speed.

It begins to more actively generated in a situation to obtain new data or reproduction of old.

Where and how is produced acetylcholine?

Acetylcholine is synthesized in the axons, nerve terminals, this portion which abuts the end of one neuron to the other of the 2 compounds:

• 1.From acetyl coenzyme A or CoA, which in turn comes from normal glucose (sweet products).
• 2.choline or vitamin B4, which a lot of nuts and eggs, in the choline acetyltransferase reaction.

Then acetylcholine in a neuron is wrapped in a kind of beads, containers, called vesicle at about 10,000 molecules. And it goes to the end of the neuron in the presynaptic terminals. There vesicles merge into the cell membrane and the contents flying out of the neuron into the synaptic cleft. Imagine an iron grid, which often pull in lieu of fences in small towns and a small bag filled with water. We throw this packet in the net, it breaks, remains on the mesh, and fly on the water. The principle is similar: acetylcholine vesicles balls sent by the end of the neuron, it "breaks" the ball was inside, and acetylcholine flying.

Or acetylcholine in the synaptic cleft is delayed, or penetrates the other neuron, and back into the first.

How it enters the second neuron? Each neurotransmitter tends to its receptor on the surface of the 2nd neuron. Receptors - this is the door to every door needs a key, a neurotransmitter. We have 2 types of acetylcholine key with which he opens the doors of type 2 in another neuron: nicotinic and muscarinic.

An interesting point: For the balance of acetylcholine in the synaptic cleft is responsible enzyme acetylcholinesterase. When you overeat certain nootropic pill, acetylcholine is increased if the amount becomes crazy, then turns on the enzyme. It destroys the "extra" acetylcholine to choline and acetate.

In patients with Alzheimer's (bad memory), this enzyme operates at high speed, good results in their treatment drugs show a temporary inhibition of the enzyme acetylcholinesterase. Inhibition of the mean inhibition of the reaction, ie drugs that inhibit the operation of the enzyme that breaks down acetylcholine, roughly speaking, make smarter. BUT!!! There is a huge BUT! Irreversible inhibition of this enzyme is too much increases the concentration of acetylcholine, it is not good. (You can improve your brain with Adrafinil, Piracetam, Noopept, Phenylpiracetam).

It causes convulsions, paralysis, even death. Irreversible inhibitors of acetylcholinesterase - this most nerve gases. Neurotransmitters becomes so much that all the muscles are literally freeze in the shortened position. If strongly narrowed, for example, the bronchi - the person suffocates. Well, now you know how paralyzing gases work.

Pros of acetylcholine:

• It improves memory, helps in old age.
• It improves the cognitive abilities of the brain, making smarter.
• Improves neuromuscular communication. It is useful in sports expense of more rapid adaptation to stress. It indirectly forces to lift more weight or run a distance faster through rapid habituation to the existing conditions.
• Acetylcholine is not stimulated by any drug, but rather suppressed, there is no reason for abuse. In most suppressed acetylcholine hallucinogens. This is logical, for the occurrence of delirium requires blunt brain.
• In general, useful neurotransmitter everyday peaceful life. It helps to plan, less impulsive decisions and mistakes. It complies with the proverb "seven times measure, cut once."

Cons of acetylcholine:

• Harmful in stressful situations where you need to act.
• It stops the body when it a lot. Look at the scientists, 90% of calm and serene like a boa constrictor. Past dragon fly - they do not move. But scientists are smart - and rightly so.

Correction: people are different and "sets" various neurotransmitters, if a person has a lot of acetylcholine and glutamate are many - it will be faster and more strongly than anyone norm. And the intellectual potential will change slightly.

The load, which increases acetylcholine in vivo:

• New information.
• Intellectual or physical training.

Supplements that increase acetylcholine (agonists):

• Racetams (Piracetam, Phenylpiracetam, Pramiracetam,Aniracetam, Oxiracetam)
• Lecithin
• DMAE
• Choline Alfostserat
• Acetyl L-carnitine
• Acetylcholine
• Huperzine
• Muscarine
• Medications prescribed for Alzheimer's disease

Supplement that reduce acetylcholine (antagonists)

• Atropine
• Diphenhydramine
• Scopolamine

What to eat for a good level of acetylcholine: Eggs (not tire of repeating), and nuts.

Bottom line:

• Acetylcholine - a neurotransmitter is not only a good mind, but also help in the sport.
• It is produced in neurons of glucose and choline. To increase their level - to improve and potentially acetylcholine.
• If it is too much - will be paralyzed, if too little - a learning disability. Usually, without serious preparations, these extremes almost never actually get. Is that closer to old age - memory problems.
• Super Brain, in theory, it is the amount of acetylcholine that was almost paralyzed + good production of other mediators.
• Good eating and develop, strain your brain and body, and you will be acetylcholine in larger quantities than 90% of your surroundings.