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Drugs that increase the production of growth hormone in the body

01 Jun 2018

Growth hormone has long been used in professional bodybuilding as a means of recruiting muscle relief. Thanks to such properties as suppression of catabolism, acceleration of muscle growth and splitting of adipose tissue, there is no safer and more effective analogue to this hormone.

recombinant human growth hormone

In this article, we will analyze the list of pharmaceutical preparations that increase the synthesis of growth hormone in the body.

The most potent stimulators of growth hormone are peptides, namely:

  • GHRP-2
  • GHRP-6
  • GRF (1-29)
  • CJC-1295
  • Ipamorelin
  • HGH Frag (176-191)
Next are the following drugs:

Clopheline and moxonidine are the most potent activators of growth hormone from available pharmacological agents.
Baclofen - is similar in effect to Gaba, but it differs better than the ability to penetrate the brain.

With regard to sports nutrition, the best growth hormone boosters present on the market are able to increase the concentration of growth hormone in the body 2-4 times. Such sports nutrition products include:
  • Fountain Of Youth HGH Complete
  • Applied Nutriceuticals HGH Up
  • Universal GH Max
  • Nutritional supplements based on arginine and glutamine


What doping do you use?

31 May 2018

The five most potent types of doping.

doping buy

Scandals associated with the use of banned drugs, occur almost monthly, but something we miss the ears. This time around the doping story does not work at all desire. Another scandal broke out a week before the start of the Olympic Games in Sochi, and it was involved in Russian biathletes. In general, in the world of doping, Russia, alas, was on the "front line". It does not take a year for our athletes not to light up in the doping scandals - the percentage of negative samples in Russian athletes is kept at a beyond the level. So this year has just begun, and already there was the "Yefimova case", now "the case of Yuryeva and Staryh" ...

In general, all this doping history is still coming from the USSR, when many coaches and doctors built their careers on what stuffed sportsmen with all sorts of drugs. Some can not stop until now. Gradually formed a list of the most popular drugs. We are trying to figure out which of them are now in the course, what kinds of sports are used and what they actually give.

1.Erythropoietin EPO
Let's start with the dope, in the use of which Catherine Yuryeva and Irina Starykh are suspected. Erythropoietin is a hormone that stimulates the formation of erythrocytes from late progenitor cells and increases the yield of reticulocytes from the bone marrow, depending on the consumption of oxygen. Erythropoietin - a kind of copy of the natural kidney hormone. After he gets into the blood, he activates the process of ripening of red blood cells.

History of appearance
The drug appeared in 1983, it was invented by American specialists. Almost immediately he was in the sport. But due to the fact that erythropoietin practically copied the natural hormone, it could not be caught. Only in the early 2000s in the French laboratory Chateau-Malabry found a way. After that, the tests of old samples were sent and almost all the famous cyclers of the past were caught using EPO. Nevertheless, then new types of EPO appeared. In particular, CERA, which was widely used by riders, but, since 2007, have learned to identify him. All this led to a whole stream of disqualifications for cyclists.

Physiological role
Erythropoietin (EPO) increases the amount of hemoglobin in the blood, so blood can carry more oxygen in the body, which improves endurance.

Scope of application
Cyclic sports: cycling, cross country skiing, biathlon, swimming, speed skating.

The loudest scandals
In 2001, at the home world championship in cross-country skiing on the use of EPO, almost all the starry Finnish team was caught - Mika Myllyul, Jari Isometasa, Virpi Kuitunen.
A year later at the Olympic Games in Salt Lake City, our turn came - the victims of the checks were Larissa Lazutina and Olga Danilova.

In 2008, the Tour de France was immediately captured by 4 people, in their blood was found a new kind of EPO - CERA. Disqualifications were awarded to the overall standings Bernhard Kohl, as well as the winners of the individual stages Stefan Schumacher, Riccardo Ricco and Leonardo Piepoli. The results of the race were revised.

Also on the application of CERA was caught a two-time world champion, a runner at 1500 and 5000 meters Rashid Ramzi. Olympic champion, he was only a few days, one of the samples taken from him at the Games in Beijing, showed the presence of blood doping.

The previous biathlon scandal involving Akhatova, Yaroshenko and Yuryeva also did not do without mentioning the EPO.

2.Anabolic steroids (testosterone, stanozolol, nandrolone, methenolone, OSTARIN)
At its core, anabolics are pharmacological drugs that mimic the effect of the male sex hormone testosterone and dihydrotestosterone. Anabolic steroids accelerate the synthesis of protein inside cells, which leads to severe hypertrophy of muscle tissue (in general, this process is called anabolism).

History of appearance
Back in the 30s of the last century, scientists learned to artificially reproduce testosterone. Then, in the 1940s, the anabolic actions of testosterone began to improve in the USSR and the country of the Eastern bloc. Until now, it is believed that track and field records established in the 80s by athletes from the former USSR countries, as well as the GDR were established with the help of steroids.
On the threshold of centuries the American laboratory BALCO tried to improve anabolic steroids, created tetrahydro-testosterone.

Physiological role
Due to the use of steroids, there is a significant increase in muscle mass (5-10 kg per month), strength indicators, endurance, production of erythrocytes increase, bone tissue strengthens, fat reserves decrease.

In principle, it is still believed that steroids are the most effective type of doping, but the trouble is that they learned to recognize it easily.

Scope of application
Track and field athletics (sprint, throwing, long jumps), weightlifting, swimming, cross-country skiing.

The loudest scandals
Scandals associated with the use of steroids pond a dime. I'll just name a few names: Ben Johnson, Carl Lewis, Marion Jones, Tim Montgomery, Frank Luc, Anfisa Reztsova, Irina Korzhanenko, Nadezhda Ostapchuk, Irina Sergeeva. The list can stretch over several dozen pages ...

3.Diuretics (chlortalidone, acetazolamide, triamterine, furosemide)
Diuretics are diuretics that are often used to remove excess fluid from the body in order to give relief to the muscles. Usually used before competitions, as the effect is rather short. Diuretics can be taken during the steroid cycle, since anabolic steroids cause excessive accumulation of fluid. Intensive urination helps to remove from the body of other dopes or mask their use by significantly reducing the density of urine.

History of appearance
In sports, diuretics appeared almost immediately after anabolic steroids came into use.

Physiological role
They help to quickly reduce body weight, improve the appearance of athletes. Dehydration helps to give the musculature of the stressed forms.

Scope of application
Rhythmic gymnastics, figure skating, athletics, weightlifting.

The loudest scandals
Most often, diuretics are used to hide the use of steroids. At the Olympics in Seoul, the Bulgarian national team won 4 gold and 1 bronze medals. However, after her representatives Mitko Grablev and Angel Genchev were caught using diuretics, the whole weightlifting team was withdrawn from the Olympics. Two Hungarian weightlifters were also caught using similar diuretics.

Quite often athletes manage to prove that the use of diuretics was not conscious, they can enter into nutritional supplements. Lately, the Olympic champion Cesar Sielo Filho and the Jamaican runner Veronica Campbell-Brown managed to "slip" from the disqualification.

4.Transfusion of blood and its components (blood transfusion) and autohemotransfusion

Blood transfusion is a transfusion, a special case of transfusion, in which the blood or its components are transfused from the donor to the recipient biological fluid.
Autohemotransfusion - transfusion to the recipient of his own blood.

History of appearance
It is difficult to say when the first time athletes resorted to autohemotransfusion, but in 1985 all kinds of transfusions were banned. It happened after the American cyclers at the Olympics in Los Angeles publicly confessed to a transfusion. The first cases of detection of such a trick after its official ban were identified already in the 2000s, after which WADA insisted on the introduction of biological passports. The system of the passport of the blood is based on its regular collection in athletes and the analysis of blood parameters: hemoglobin, erythrocytes and reticulocytes. An increase in the level of blood cells and hemoglobin leads to an increase in the function of transport of oxygen from the blood to the muscles, and consequently, to an increase in working capacity.

Often, the increase in the level of red blood cells and hemoglobin is associated with various types of transfusions.

Physiological role
Autohemotransfusion accelerates the delivery of oxygen to the muscles, thereby increasing their productivity.

Scope of application
Cycling, athletics, cross country skiing.

The loudest scandals
The first on blood transfusion was caught the Olympic champion 2000 in the race with a separate start American Tyler Hamilton.

Olympic champion of London Kazakhstan cyclist Alexander Vinokurov at the Tour de France in 2007 was also caught on blood transfusion and disqualified for 2 years. According to the experts of the Châteaune-Malabry laboratory, where the analysis of the doping test was conducted, Vinokurov's blood transfusion was performed on July 21, the same day when the 13th stage was won. In this regard, Alexander and the whole team of Astana (at the request of the leadership of the Tour de France), left the French grand tour.

5. Stimulants of mental activity (cocaine, ephedrine, ecstasy and amphetamines)
In acute conditions, stimulants rapidly change the functional indices of brain activity (activate the bioelectrical activity of the brain, change conditioned reflexes, etc.), increase endurance to physical work. In conditions of clinical use, they have a rapidly onset stimulating effect, are widely used in practice for the treatment of diseases accompanied by drowsiness, lethargy, apathy, asthenia, depression. Increasing the functionality of athletes under the influence of stimulants is largely due to the blockade of physiological regulators, the boundaries of the mobilization of functional reserves.

History of appearance
Different kinds of stimulants appeared in sports at different times. In particular, ephedrine appeared on the horizon in the late 70-ies of the last century.

Physiological role
These drugs increase vitality, reduce fatigue, stimulating an increase in training time or performance at competitions.

Scope of application
Absolutely any kind of sport - from boxing to rhythmic gymnastics.

The loudest scandals
At the Olympics in 1976 in Innsbruck in the body of the Soviet skier Galina Kulakova was found ephedrine. True, Kulakov was removed for only 1 race, as it was proved that ephedrine was found in her body due to the use of a nasal spray. This disqualification was the first in the history of disqualification for the use of prohibited drugs in competitions skiers at the Olympics.

In 1994, the famous Diego Maradona was disqualified for 15 months for the use of ephedrine in the World Cup.

On the use of ephedrine and pseudoephedrine, the famous American athlete Carl Lewis came across, but he was never disqualified, and he managed to convince everyone that the cough medicine was at fault ...

In 2011, on the use of ephedrine was caught Ukrainian biathlete Oksana Khvostenko.


Peptides GHRP-6 and their use in bodybuilding

30 May 2018

GHRP-6 is a peptide that promotes the synthesis of growth hormone. Initially, this drug was invented for the treatment of people suffering from a deficiency of growth hormone in the body, but over time it has become quite popular among the representatives of power sports (including bodybuilding).


By its structure and properties, GHRP-6 is similar to GHRP-2 - the main difference is that GHRP-2 enhances appetite, and also increases the concentration of prolactin and cortisol. Despite some differences, these peptides may well be used together - in this case there will be a synergistic effect (mutual enhancement of each other's properties). This was confirmed by scientific experiments that showed that the maximum level of growth hormone in the blood of an athlete was observed with simultaneous reception of GHRP-2 and GHRP-6.

GHRP-6 can be taken in a variety of ways - under the skin, ingestion, under the tongue, but the most popular method is intramuscular injection.

His popularity in bodybuilding this drug was due to the fact that he helped to increase endurance, and also to increase the relief of muscles.

Basic Properties of GHRP-6

  • Increasing strength
  • Muscle growth
  • Burning of subcutaneous fat
  • Strengthening immunity
  • Strengthening bones
  • Anti-inflammatory action
  • Protection of the liver
Since GHRP-6 leads to an increase in the secretion of growth hormone, its properties are similar to those of growth hormone.

According to the research, the drug GHRP-6 significantly increased the concentration of growth hormone within 30 minutes after administration. Elevated levels of growth hormone were observed within 3-4 hours after injection, then dropped to the initial value.

How to take GHRP-6?
The optimal dose of GHRP-6 is 1 μg per 1 kg of body weight. With the use of lower standards, the increase in production of growth hormone decreases. When using higher dosages, an additional increase in the concentration of growth hormone is not observed.

The total duration of the course should not exceed 4-8 weeks. It was proved that long courses (up to 16 weeks) led to tolerance of the organism, reducing the effectiveness of GHRP-6. The optimal break between the courses is 1-2 weeks.

The problem of reducing the sensitivity of the body to GHRP-6 is effectively solved by the additional administration of CJC-1295.

Combination with other drugs
The effectiveness of GHRP-6 can be significantly increased by combining it with the use of other drugs:

  • CJC-1295 - is the best combination to date, enhancing the effect of GHRP-6 six-fold
  • GHRP-2 - increases the efficiency of the course by an average of 2 times
  • Insulin - increases the effectiveness of the course by 30-40%
  • Arginine - increases the effectiveness of the course by 10-20%
  • Glutamine
  • GABA
Side Effects of GHRP-6
In the course of numerous studies of side effects or pathological changes in the body from taking GHRP-6 was not found. In addition, GHRP-6 helped improve the protective properties of the body. When using super-large dosages (more than 600 μg per day and higher), an increased production of prolactin and cortisol is observed.

At the injection site, a burning sensation can be observed, which completely disappears within 10-15 minutes.


Peptides of GHRP-2 and their effect on muscle growth

29 May 2018

Peptides of GHRP-2 and their effect on muscle growth

The GHRP-2 stimulator is by far the most effective drug that increases the production of growth hormone. Its peculiarity is that it is able to penetrate through the vessels of the oral cavity and directly enter the bloodstream, bypassing the liver. I study the effects of GHRP-2 on the human body, it was found that it stimulates the pituitary gland, which in turn raises the production of growth hormone 7-15 times. At the same time other additives based on amino acids can increase its secretion only 2-3 times.


GHRP-2 is a peptide consisting of 6 consecutive amino acids. It was first discovered at the end of the last century. This stimulator of growth hormone (somatotropin) has a small molecular weight, due to which it easily penetrates the mucous membrane of the oral cavity. The effectiveness of this method of GHRP-2 has been proved by numerous scientific studies.

For example, in 1997, the results of scientific research published in the popular Journal of Endocrinology and Metabolism showed that the use of GHRP-2 increases the secretion of growth hormone in both adults and children.

Effects of GHRP-2
Stimulation of somatotropin (growth hormone);
Improving appetite;
Reduced fat mass and increased muscle;
Strengthening of bones;
Decreased cholesterol;
Protection of the liver;
Anti-inflammatory effect.

How to take GHRP-2?
According to scientific studies, the increase in secretion of growth hormone directly depends on the volume of application of GHRP-2 and does not depend on sex, age or other factors.

Those engaged in bodybuilding, is recommended to take GHRP-2 at a dosage of 50-100 mg per 1 kg of body weight. Thus, the average dosage for an athlete is 2.5-10 mg. It must be said that the sports nutrition manufacturers nowhere indicate GHRP-2 a share in its supplements, which may mean that they use a lower dosage, which will not have the desired effect.

Additives based on GHRP-2 can be combined with other sports nutrition products, such as arginine, GABA, glutamine. This will lead to an even greater increase in the production of growth hormone. In addition, this combination is completely safe for health.

GHRP-2 Side Effects
Numerous scientific studies have shown complete safety and no side effects when taking supplements based on GHRP-2. This stimulant has undergone clinical trials and observations for 30 years, so negative impact in the future is also ruled out.


Peptide GRF (1-29) (Sermorelin, Sermoreline) and its use in bodybuilding

28 May 2018

Peptide GRF (1-29) (Sermorelin, Sermoreline) and its use in bodybuilding

GRF (1-29) is a peptide hormone of the GHRH class, which increases the synthesis of growth hormone in the body. This peptide, most often, is sold under the trademark Sermorelin (Sermorelin).


Features of Sermorelin GRF (1-29)

The main feature of GRF (1-29) is a very fast half-life in the body, which is only a few minutes (5-10). For this reason, the classical forms of GRF (1-29) provide a weak increase in the concentration of growth hormone and, accordingly, have low efficiency.

The exception is GRF (1-29) Mod - tetrasubstituted or modified GRF (1-29). Its feature is the additional 4 amino acids included in its composition and providing a half-life of about 30 minutes. This provides a longer lasting effect and significantly better stimulation of growth hormone production in the body.

GRF (1-29) and CJC-1295
Very often GRF (1-29) and CJC-1295 DAC confuse each other, however, having similarities in structure, they differ significantly in action. Thus, CJC-1295 DAC is a modified peptide of the GHRH type, which contains the amino acid lysine, which is bound to the molecule Drug Affinity Complex (DAC). This combination allows the CJC-1295 DAC to have a half-life of 1-2 weeks, which is much more convenient, since it allows injections only a couple of times a week (instead of 1-3 times a day).

Dosages and course GRF (1-29) Sermorelin (Sermorelin)
The optimal dosage of GRF (1-29) Mod is 100-200 μg, taken 1-3 times a day in the form of subcutaneous or intramuscular injections. The total duration of the course is 6-12 weeks.

The optimum is the combination of GRF (1-29) with the reception of peptides like GHRP in the following course:

Serrorelin GRF (1-29) - 100-200 mcg;
GHRP-6 or GHRP-2 - 100 μg;
Peptides must be dissolved in 1-2 ml of water and administered 1-3 times a day;
The optimal time of reception: 15 minutes before meals, immediately after training and before bedtime.

How to make a solution of GRF (1-29)?
Take the vial and cool it to room temperature;
Add the necessary amount of water for injection (the addition of water should be carried out by draining it along the wall of the bottle);
Stir the resulting composition (do not shake or shake, but use circular rotational movements);
The resulting composition can be stored in the refrigerator without freezing for 8-10 days (with the use of bacteriostatic water - up to 30 days).

Important! Tetra-substituted (modified) GRF (1-29) Mod is best dissolved only in bacteriostatic water.


Increase the synthesis of growth hormone in the body

25 May 2018

In my previous articles, I talked about how to stimulate the production of growth hormone due to dietary supplements. Meanwhile, there are quite natural sources of increasing the level of this hormone in the blood.

- Do not eat fatty foods 4 hours before the workout

It is proved that the intake of fatty foods before training reduces the response production of growth hormone by 50%. Therefore, before going to the gym, choose sources of protein that do not contain the minimum amount of fat - whey protein, chicken breasts, turkey, tuna, low-fat or low-fat dairy products.

- Before the exercise, consume "slow" carbohydrates

The intake of "fast" carbohydrates leads to a powerful release of insulin, which not only hampers the burning of fat, but also reduces the secretion of growth hormone. Therefore, it is recommended during this period to refuse such food.

- Take food supplements

Scientific studies have shown that a large amount of arginine, glutamine and melatonin significantly increase the release of growth hormone into the blood. In this regard, it is recommended to drink 5-9 grams of arginine, 5-10 grams of glutamine and 0.5-5 mg of melatonin 30 minutes before taking the protein cocktail.

- Do not neglect the workout

Other studies have shown that as the body temperature rises, the level of growth hormone also increases. Therefore, before the start of training, it is recommended to hold a small 5-minute cardio-warm-up, then perform 2-3 warm-up approaches of the first exercise. This will increase body temperature and positively affect the level of growth hormone in the blood.

- Apply aerobic workouts

It is noticed that if you use cardio-loads before strength training, then the level of growth hormone will fall 3 times. However, if immediately after strength training go to cardio, on the contrary, the production of growth hormone will increase. It does not matter with what intensity you perform aerobic exercises - equally useful as a slow, and fast pace.


Side effects of taking HGH

24 May 2018

HGH has been used for a long time by many professional athletes. Since this hormone is produced naturally in the body, the side effects from its administration are quite rare and arise mainly when using large doses over a long period of time.

growth hormone side effects

Possible side effects of taking growth hormone:

Tunnel syndrome - characterized by pain and numbness in the extremities. The main reason for such manifestations is an increase in the volume of muscles that begin to squeeze peripheral nerves. As a rule, this syndrome disappears with a decrease in dosages.
Fluid accumulation in muscles - this side effect is inherent in many hormonal drugs (used for anabolic purposes). Try to minimize this effect by reducing consumption of salty foods and giving up alcohol.
Increased blood pressure. Eliminates either by reducing dosages of growth hormone, or by taking antihypertensive drugs.
Oppression of the thyroid gland function is weak. To eliminate it, on a course of reception of a growth hormone it is recommended to accept the Thyroxine (25 mkg a day). It is worth noting that after the course ends the function of the thyroid gland is completely restored.
Hyperglycemia is an increase in the level of sugar in the blood. This side effect is eliminated with the help of an additional intake of insulin or drugs that stimulate the pancreas (for example, Diabeton).
Acromegaly - observed when using elevated doses of growth hormone for a long period of time. At observance of moderate doses does not meet.
Hypertrophy (increase) of internal organs - occurs only in the case of very large doses of growth hormone.

The side effects of growth hormone, not confirmed by official science:
Increase of abdomen.

There is an opinion that the intake of growth hormone over time leads to an increase in the abdomen (due to the hyperplasia of the internal organs due to the receptors of IGF-1). At present, this fact is not confirmed by science, but the experience of some professional bodybuilders shows that this can be the case. Experts explain this by the fact that many professionals take large doses of growth hormone in combination with other anabolic steroid, which indirectly can affect the increase in the abdomen.

Impotence and infertility.
According to research, the use of GR in an anabolic manner did not lead to pathological changes in sexual function.

Suppression of the production of its own growth hormone.
According to studies by professors Elmer M. and Cranton M., in more than 100 patients taking growth hormone, there was no suppression of the function of intrinsic GR production.

Development of tumors.
There is an opinion that the intake of growth hormone can accelerate the division of cancer cells. Wishing to verify this fact, the researchers conducted a study, which found that patients suffering from tumors and undergoing growth hormone treatment did not experience deterioration.

Correct conclusions
Taking any hormonal drugs for anabolic purposes leads to irreversible effects on the body. Safe steroids are not and can not be. The use of these drugs to build muscle mass and strength can be justified only if the athlete earns performances with money or has the status of a professional (which is generally the same thing), soberly aware of the consequences of such a sporting career.


Peptides in bodybuilding: properties, effects, influence on muscle growth

23 May 2018

Peptides are a family of substances whose molecules are built on the residues of alpha-amino acids linked together by a peptide chain. These substances can be both vegetable and synthetic origin. In this article, we will consider only those peptides that can be used to enhance the physical performance of the athlete.


At present, peptides aimed at stimulating the production of growth hormone are widely used in the pharmaceutical market. These include:

The Grelin group (GHRP) - the main feature of this group is that the increase in the production of growth hormone occurs immediately after administration.

This group includes:

  • GHRP-6 and Hexarelin
  • GHRP-2
  • Ipamorelin

Growth hormone releasing hormone (GHRH) group - when using this group of peptides, the increase in production of growth hormone occurs during hours of natural increase in the secretion of growth hormone (for example, at night); at other times, the increase in production will be insignificant.

This group includes:
  • GRF (1-29) Sermorelin
  • CJC-1295

Benefits of taking peptides

Many athletes may have a question - why take peptides, if it is much easier to use artificial growth hormone? It should be noted that peptides in this regard have several clear advantages:

Significantly lower price, compared with the growth hormone
Taking peptides, it is possible to flexibly control the concentration of growth hormone in the blood, thus achieving a better anabolic response
The production of peptides is not regulated in any way by the law, and therefore they can be acquired legally
The rapid peptide decay period leads to the impossibility of determining them in the body of an athlete during doping tests
Preparations based on peptides can be easily verified for authenticity - for this it is enough to pass tests for the content of growth hormone (somatotropin) in plasma after taking the drug.

Scientific basis for effectiveness
Scientific research conducted in 1998 (Bowers CY: Growth hormone-releasing peptide (GHRP), Cell Mol Life Sci 1998, 54 (12): 1316-29 and Camanni F, Ghigo E, Arvat E: Growth hormone-releasing peptides and their analogs, Front Neuroendocrinol 1998, 19 (1): 47-72) showed that peptides of the GREEN group (GHRP), as well as other non-peptidic substances aimed at increasing the production of growth hormone, really affect its synthesis.

These studies served as a powerful impetus to the creation of food additives that increase the production of growth hormone. At the moment, there is evidence that these supplements actually work - the increase in growth hormone and IGF-1 was observed both at rest and in the course of strength training. However, the effect of these processes on the increase in dry muscle mass was not observed.


Peptide CJC-1295 DAC: Features, dosage, methods of administration, side effects

22 May 2018

Peptide CJC-1295 is a peptide hormone consisting of 30 amino acids and functioning in the body as a natural stimulant for the production of growth hormone.


The main advantage of CJC-1295, in comparison with GRF (1-29), is a longer decay period and, as a result, a much longer period of action.

Peptide CJC-1295 DAC in bodybuilding

CJC-1295 DAC was invented in 2005, but it was widely used in bodybuilding by 2010-2011. It was during this period that a number of third-party companies mastered the production technology of this peptide, which led to a large-scale popularization of CJC-1295 and peptides in general.

The main activities of CJC-1295:

  • Increased muscle mass
  • Burning of subcutaneous fat
  • Increased muscle strength
  • Strengthening of joints, ligaments and bones
  • Improve skin quality (reduce wrinkles)
  • Normalization of sleep
What does the DAC mean?
DAC stands for Drug Affinity Complex and is a non-peptide molecule linked to the amino acid Lysine. This ligament can significantly increase the action time (up to 2 weeks) of the peptide and achieve higher results comparable to the intake of the course of growth hormone.

When choosing peptide CJC-1295, be careful and specify in advance whether there is a DAC. Very often under the guise of the CJC-1295 DAC, the sellers offer GRF (1-29), the action of which is only 30 minutes (for the modified version (Mod), for the usual - 5-10 minutes), which is clearly not enough to get any tangible results.

How to take CJC-1295 DAC?
The optimal dosage of CJC-1295 DAC is 1000-2000 μg, taken 2 times a week: at the beginning of the week (Monday) and at the end (Saturday).

To obtain a better effect, the administration of CJC-1295 DAC can be combined with the administration of other peptides, GHRP-6 or GHRP-2. The optimal course is as follows:

GHRP-6 or GHRP-2 at 100 mcg - 3 times a day;
CJC-1295 DAC for 1000 mcg - 2 times a week.

The total duration of the course is from 8 to 12 weeks.


How to increase testosterone levels in men

21 May 2018

How to increase testosterone levels in men: dietary supplements and drugs

In our last article, we analyzed the main natural ways to increase testosterone levels in men. Today we will talk about food additives and preparations that also contribute to the production of male testosterone. Immediately make a reservation that it will not go for anabolic steroids, although some of the drugs considered are on the list of prohibited doping drugs.

Who are these drugs for?
- Men older than 20-23 years, whose goal is a set of muscle mass;

- Men over 30 and 40 years of age for the growth of muscle mass, potency and libido;

- Athletes after courses of anabolic steroids - to stimulate the development of their own testosterone, reduce the "phenomenon of recoil" (muscle destruction).

Who does NOT use these drugs?
- Men younger than 20-23 years old have a naturally increased testosterone level and an unstable hormonal system, so they do not need additional stimulation. Otherwise, there may be a significant decrease in the production of their own sex hormones.
- For girls, as stimulation of testosterone production leads to the development of masculinization (accumulation of secondary sexual characteristics of the male sex).

Drugs and supplements to increase testosterone in men
Letrozole - this drug is an aromatase inhibitor that increases testosterone production by 50% and reduces the synthesis of estrogens. To this type of drugs are also Anastrozole and Exemestane.
Tamoxifen - the drug reduces the production of estrogens in the body, thereby increasing the concentration of testosterone (142% of the initial level).
Proviron - increases the level of free testosterone, improves potency and libido, compensates for the inadequacy of producing their own sex hormones.
Vitamin D - a number of scientific studies have revealed the dependence of the level of vitamin D and testosterone.
Forskolin - is a component of the plant Coleus forskohlii. Promotes increased testosterone production, increased dry muscle mass and increased potency.
Agmatin - a number of studies have proved that this substance helps to increase the production of gonadotropin and gonadoliberin, which also affects the synthesis of its own testosterone.
Tribulus (Tríbulus terréstris) - food additives based on this plant increase the synthesis of testosterone in the body, sexual activity and libido.

Dosages and courses of admission
When taking any of the above drugs should follow the manufacturer's recommendation. The optimal course duration is 4 weeks. The greatest effect from taking is observed with the use of adequate physical exertion, as well as observance of the correct diet, rest and intake of food supplements for the growth of strength and mass - protein and creatine.

Important! Choose only one product from the list above. Combine 2 or more drugs to increase testosterone can not! Also, you can not use them in combination with taking anabolic steroids and prohormones.

Side effects and contraindications
Any drugs that increase the level of testosterone in the body, affect the synthesis of your own hormone, suppressing it. Especially it affects when using higher doses and long courses of admission. Therefore, it is recommended to follow the recommendations of manufacturers strictly and not to practice courses for more than 1 month. In this case, this side effect is almost not found, although no significant growth of muscle mass also occurs.

In rare cases, the following side effects may occur:
Aggressiveness and irritability
Unstable blood pressure
Testicular Atrophy
Hair loss
Feminization (development of secondary female sexual characteristics)

Almost all side effects completely disappear when discontinuing medication.

Do not take these drugs for heart disease, kidney failure and arterial hypertension.

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