Alcoholic tremor - symptoms, causes, treatment

Symptoms of alcoholic tremor

Alcoholic tremor in acute poisoning with alcohol often manifested as shaking fingers. This is a kind of physiological tremor. He appears only in the morning with a hangover, and after drinking even a small ( "hangover") doses of alcoholic beverage is reduced or disappears. Without taking liquor tremor gradually weakens and disappears during the day.
Alcoholic tremor in advanced stages of alcoholism - it is certainly a pathological tremor. It manifests itself in trembling fingers, hands, head, and sometimes the entire body. Disturbed coordination of movements, may appear tremor tongue, eyelids.
As far neglected stage of alcoholism tremor may persist for several days or weeks. Often, it is noted sleep disturbances, poor general health, lethargy.
The flow depends on the age of the patient, from the static loads. With more and more difficult, there may be a tremor eyeballs, vocal cords, abdominal muscles alcoholic tremor occurs over time. It may also be a violation of gait, alcoholics often fall.
Alcoholic tremor develops and withdrawal syndrome (a condition which develops in people suffering from alcoholism, after the cessation of alcohol consumption, with output from binge).

Causes
Alcoholic tremor is the result of the toxic effects of alcohol on the brain and spinal cord, resulting in growing alcoholic encephalopathy. Motor nerves, cells stop braking interact with each other, as a result of having expressed incoordination.

Treatment of alcoholic tremor
Alcoholic tremor to be treated in a hospital under the supervision of a physician because Some drugs have an effect on the cardiovascular system.
The complex treatment includes detoxication therapy, helps to eliminate toxins from the body.
For proper treatment of tremor using Propranolol, Primidone, Phenotropil . The choice of drug and its dosage depend on the age of the patient, and on the presence of comorbidities, so treatment can appoint a qualified doctor.
The combined therapy also include vitamins, magnesium drugs, calcium channel blockers, anti-anxiety drugs. Of course, it should be completely ruled out the use of alcoholic beverages.

L-Theanine - attention to detail

Today let's talk about supplements derived from green tea leaves that has a very interesting property! You can drink tea for years and did not even suspect that you prefer the effect that it is L-theanine.

So L-theanine - a substance that is similar to both the major excitatory neurotransmitter in the brain - and the main inhibiting glutamate - GABA. This duality incorporates some of the common points of these mediators. According to the results, we can say that L-theanine 2 to 1, but as always, first things first.

How does L-Theanine act?

• Anti-stress. L-theanine improves overall health research. A double-blind placebo-controlled study showed a reduction in heart rate and sympathetic nervous system activity. That is, the subjects were not only effect on the brain, but also on respiration, blood circulation and digestion.
• Nootropic action. L-theanine is a miracle-pill for people who need a quiet sanity and a high concentration of attention. Perhaps the most well-known effect of L-theanine - an increase of alpha activity in the brain! But what is it? It is a state of peace, ease, but without causing drowsiness!
• Reduces side effects of stimulants. This we will recall later, but there is evidence that when taken with caffeine, L-theanine smooths out increasing pressure and dilates blood vessels in the brain. At the same time it improves the intellectual function of the brain.
• It helps with schizophrenia. This action follows from the preceding paragraph. It has been speculated that time schizophrenics are so exaggerated activity of the dopamine, a man like all the time on strong stimulants. At the University of Cambridge decided to test L-theanine on sick people, together with the classic treatment, participants received an additional 250 mg of L-theanine. The results are not phenomenal, but there were unambiguous improvement in sleep quality.
• Neuroprotection. Protect nerve cells, or by the example of Parkinson's disease. Visually, the disease is seen in constant twitches different parts of the body, most notably in the elderly. This is due to motor neuron death! L-theanine is a serious obstacle to the process, through increasing neurotrophic factors.
  In almost every issue you are used to hearing that the substance acts on neurotransmitter systems. L-theanine is practically no effect on neurotransmitters except GABA.

Course L-theanine
During the time of this writing I have not heard a single study, which would be said about contraindications and side effects, even when the children received. Therefore, we point out the standard: "With care for pregnant / lactating women, as well as in childhood due to the understudied additives in these categories of people."

L-theanine - it can be said squeeze of green tea. People for years drink green tea every day, therefore, the additive can take any number of times. The question is dosage. And they are different! Different content and L-theanine in the tea. Depending on the types of tea brewing and method for cup volume 200-250 mL, was obtained from 8 to 40 mg of L-theanine. Let the average is 20 mg. You can also like Picamalon.

Accordingly, a daily intake of 50 mg of the additive can be considered safe for continuous use. What sways higher dosages, the long-term data is not enough.

Let us consider the recommendations of 50-100 mg per day, if you are going to take almost every day, or 400 mg, if from time to time.

The effects of L-theanine
The most important and tangible action of the additive is manifested in the increase in alpha activity in the brain and acts on the GABA system. You will become calmer, but without losing mindfulness. Something like the feeling of fishing. On the one hand, you do not need to run and jump, and do not want the other - always keep a float or other "bite" marker.

Alpha activity (8-14 Hz) precedes beta activity (14-20 Hz), when there is a specific action, as an example: watch the float and tie up gear. Prior to alpha activity are Theta waves (4-8 Hz). Status prostration or meditation. And up to 4 Hz - failure condition in a dream and the dream itself.

What combine with L-theanine
As you know, L-theanine itself more as a relaxant and "increaser attention." But everything changes when you add to it at least approximately identical to caffeine dosage of, say 200 mg of theanine and caffeine 200-300. With this bundle, we get all the advantages of caffeine and reduce its side effects. Sharply increased focus and efficiency of virtually any activity.

Emphasis has been going on is on the brain! For L-theanine observed reduction in pressure, heart rate and expansion of brain vessels, and caffeine or any other stimulant almost always does the opposite. In general, L-theanine + stimulant = displacement activity in the brain, not the body, if we talk quite exaggerated. And to get a better feel on the background of stimulants, it is sometimes useful to drink green tea)

Bottom Line:

Dietary supplements for some reason considered to be something on the level of the placebo, although the same caffeine also formally supplements or supplement, not a drug. Try to drink a liter of energy and "placebo" blow you from head to toe))
- L-theanine - It really works additive, besides, pretty safe, a lot of research, you can check how much you want. This substance is likely to be in this second small shop, after the DMAC.
- This supplement works through changes in brain activity, GABA system, protection of neurons and relaxation of the nervous system.
- Effects: Calm, Care, ease pressure lowering and heart. The additive is useful for increasing the concentration, when everything moves and makes a noise and it is impossible to concentrate.
- L-theanine's great combined with caffeine, significantly improving the effects of the latter and reducing side effects. It is also possible positive effects with other stimulants. So that the effects will be even better with them.

Life hacking - Motivation, Getting Smarter

Our project is engaged in the brain, hormones, neurotransmitters, and not for someone already knows that concepts such as "happiness", "enthusiasm", "motivation" are controlled substances that are already in us and are produced depending on the situation. What is the matter? Dopamine, serotonin, phenylethylamine, norepinephrine, oxytocin, adrenaline and others. Then talk about the specific cases, what to do.

Now there is such a theory that certain proportions in hormones and neurotransmitters play a more important role than a high level of one of the main. Example heard probably about the equalizer in the music, that is, we listen to music and can adjust various settings, and if we want to better hear it, stop it at this adjustment. Words will be better heard, but the song itself is distorted. And it will be more appropriate to adjust other settings. About something similar happens with the brain.

The easiest way to do this: to arrange their own food, then you will understand why and to diversify their enthusiasm for the different emotions that you would like to coach the selection of different substances. Next, the body has very wisely reconstructed depending on what you need.

Motivation
So, the first thing that people are often interested in - "motivation", what kind of animal? Why are some so pret some activities that they do around and do not see, and the other hung himself with all sorts of quotes, read motivational books, seemed to know everything, but it turns out the circuit from one motivator to the other, and there is no specific action.
Generally it is believed that this process is not available dopamine. Let's just dopamine - it is the driving force, it is not the only one, as mentioned earlier.
The point about motivation, we will talk about dopamine, but you must understand that much more important to observe the proportion in everything.
Dopamine is not only motivates, but also allows you to concentrate. Not without reason in patients with schizophrenia, this mediator is through the roof, and they can not concentrate on some images.

So how to increase dopamine?
The main condition - a task or a goal on what you need to concentrate. + It is important to come up with a "why" needs this goal. How can you visualize brighter.
Remember how we as a child anticipating certain events, fantasized, sometimes could not sleep and were like inflated - work dopamine. Something similar is necessary to come up with now.
Well now we are adults and we can understand the logic that still need a plan of action and mini-goals, not just fantasy.
From the perspective of biology, dopamine generated from tyrosine and phenylalanine. This amino acid present in the protein product. A rule carbohydrates and fats in the modern world: fast food, candy, soda, etc. So that the protein to all! Perhaps because of his lack of you have little motivation and no spark in his eyes. From the legal and available supplements, for an increase of dopamine was seen by caffeine, can be used.

How to become "liberated"?
Often, all a matter of the nature and instincts: to be charismatic, choleric upstart in all holes gag was not always appropriate. And modesty and closeness sometimes even welcomed. As with dopamine in our brain, a substance that can be said to be responsible and "emancipation". Unfortunately, it also has disadvantages, such as carelessness and irresponsibility. Some probably already guessed).

This substance is very strongly activated alcohol, and enslaved alcoholics and probably does not exist, they do not care at all. And, as you know, the level of courage and candor grows in direct proportion to the amount of alcohol consumed ...

Gamma-aminobutyric acid or GABA - inhibitory neurotransmitter. For him and the sea generations. One well-known Russian scientist - cited statistics that consumption of no more than 20 ml of pure alcohol for men and 10 ml for women is even useful dosage per day. I leave this point at your discretion) And the project is often criticized that saying banal things, supposedly healthy lifestyle, sports, etc.
GABA is produced from another neurotransmitter - glutamate, GABA contrast, under the influence of vitamin B6. Now perhaps you understand the meaning of such a popular supplements like MagneB6. It allows a natural way, as if the interpreter, to transform part of the glutamate into GABA. Another additive increase GABA: Melissa and St. John's wort.
And yet, if quite frankly, for the concept of "liberated" need to put pressure on the psychology, to become bolder, and of all that.

How to be smarter?
Also popular and broad question. I do not want to talk too banal things like "read the book and study the science." Undoubtedly, these methods work, but you do not listen to this point because of what has long been know.
So, our intelligence, our memory can be evaluated by including the number of synapses in the brain. Synaptic connections - is the connection between nerve cells in the brain. They seem to keep our memories. And most interestingly, when we forget something, in fact, we do not forget anything, just a chain of nerve cells, the chain of synaptic connections if waning. Probably noticed how easy it is to recover old skills and how hard it is to turn out new ones.
Getting smarter - is the hard way, a way of creating new connections, rather than the old workout. Of course, if you say, photographer or a mathematician or an insurance agent, the profile direction must continuously strengthen and improve professionalism. Here we are talking about minor things. We strive to diversify the life as if you will die in six months, but I wanted so much more to do. It was a new experience and create synaptic connections.

You see, the brain is like a lot to learn, to gain some experience. And even a small new information somewhere postponed in our skull. Therefore, summary: you can read a book, and you can travel, you can explore the science, but you can learn to play guitar. It all depends on your taste preferences. The main thing is to develop some sort of main direction, if any, and to try minor, if they are interested.

Additives to improve the mental abilities are called nootropics (Semax, Phenylpiracetam, Noopept). They have a lot of groups, but their common goal: either facilitate the acquisition and processing of information, or to speed up the establishment of synaptic connections and nerve cells. They themselves in the head did not load.

Bottom Line:

- To motivate and dopamine caffeine + to make a plan for a purpose, that purpose paint in bright colors.

- For the "emancipation": lemon balm, St. John's wort, alcohol (like it or not, but it is legal and non-prescription) + work with psychology.

- For the mind: nootropics + + development of a new experience.

How to struggle with stress?

What is stress? As with any disease, stress can be acute and chronic. Acute stress - stress is temporary. Whether it will lead to severe depression or not, it depends on the person. If a person is able to mobilize its forces withdraw from this stress, he defeated him.

It can only be strong people, those people who find the strength to calm down. Indeed, while it is impossible to bring back, what happened can not be changed. Why then wag your nerves? After all again tomorrow a new day, life goes on, and to strive to make this a good and happy life. You can not stop and say, "Nothing I want. I can not. " If all the time to say these words, you will see only the diagnoses of doctors' heavy depressive syndrome "," chronic stress. " You can help yourself with this struggle by Selank, Afobazole, Phenibut, Phenazepam.

Believe me, it's up to no good arguments. If you are heavy, often hop off from society, be in nature, to bring up the tranquility. Mental hospital - not salvation.

Be like children draw in the sand, collect stones. Listen to nature. Remember that fire and water, you can watch endlessly. Light a candle, open the valve. Be like a Persian cat looking out the window and enjoying even a drop of water. And in the winter and you can sculpt a snowman! In my spare time I try to do what you like, not through force, but through pleasure. Stress is very dangerous, especially for the thyroid gland. Do not allow your body to depression. After all, man is born not for her, and born for happiness as a bird for flight. Let these words be your motto in life.

Eloquent Symptoms of Depression

People who suffer from depression or some kind of manic disorders typically manifest or show one or more symptoms that, as the doctors say, these patients should have. Sometimes it is very easy to miss the signs of these symptoms in yourself or in your family, and not be able to help them in this situation.

There are many symptoms of depression, which show sick people. The most important thing is not to force people to suffer from this, and the time to diagnose and begin treatment of this disease. Since the disease symptoms vary widely, and that the attacks of the disease is also different. You can cope with depression with Afobazol, Phenibut, Selank and Phenazepam.

Below I will give some general signs of this disease:

1. People who are experiencing long-term depressed mood or insensitive to external stimuli, people who are always in a bad mood, who are willing to spend days wandering around the house and feel guilty in front of himself a great example for the symptoms of depression.

2. Feelings of hopelessness, pessimism long: saying or feeling sorry for ourselves always is another common symptom of depression where a person does not see anything promising and promising in their lives. If a person shows prolonged pessimism, he experiences a negative attitude to many things, which again gives rise to utter hopelessness of what is happening in his mind.

3. Fill the guilt, the catastrophic decline in self-esteem and helplessness - that's one more standard features of the doldrums. These symptoms are easily seen in people who hang out all day at home doing nothing. The constant presence of guilt in front of everyone and everything, to cause the soul of such a person the feeling that he does not deserve happiness. Thus, ironically, self-reduction under the influence of an oppressive sense of the impossibility of being happy and enjoying life is a clear symptom of depression. Helplessness also contributes to the strengthening of the doldrums, when there is a feeling that all is not as it should, and this is another symptom of the disease.

4. Lack of interest in the experience of pleasure or searching for those things that used to cause pleasure, uninteresting; These symptoms show how people can be exposed to the disease. If a person is a long time in a depressed state, does not enjoy those activities that were previously enjoyed doing, emerged feeling of lack of something is possible he is captured by depression.

5. Indifference and apathy, constant fatigue, people experiencing mental suffering from what is happening since lost interest in life and did not possess the physical energy that they had before. But people can not just deal with idleness, and they have no interest in food, they are enough sleep, which negatively affects their physical health too.

6. When depression is impossible to concentrate, and memory is deteriorating, which affects the person's ability to interact with the outside world. Since man is closed and occupied only by their state, he can not keep track of the relationship of what is happening in the outside world and, hence, is not able to remember what other people say or what was going on around him. Lack of interest in the outside world makes people very inattentive.

Of course, there are many more symptoms, which can be understood that a person is sick and needs doctor help: lack of sleep, or a surplus, the constant waking up because of voiding all the symptoms of depression (unless, of course, they happen every day). Overeating or loss of appetite also show a lack of vitality. Sudden weight loss or vice versa set, increase suicidal desires, talk of death or wanting to die one more symptoms of a depressive state. As a result of these deviations is easily disrupted physical state: problems with the gastrointestinal tract and headaches. 

Symptoms and Causes of Depression

Depression is becoming one of the most common mental illnesses of our time. Why is this happening? The whole rhythm of modern life aggressive to the human psyche. Each of us has one chance in five during the life of developing depression. There are categories of people who are more susceptible to this disease. Risk of depression that often end in severe cases of depression, attempted to commit suicide.

Symptoms and causes of depression of different sex and age people can be very different. And the fair sex suffer from depression twice as often as men. It turns out this is due to the constant changes in hormonal levels in women of childbearing age.

If your friend is suffering from depression, you will notice that her mood has changed considerably. Perhaps it has become more inhibited, or vice versa - aggressive. She may develop drowsiness or insomnia. A woman in a state of depression can not normally focus on work, she was crying over nothing and constantly concerned. You can see and change in appetite. It can be two extreme conditions: a woman eating everything in large quantities or can not eat at all. Frequent absolutely unexplainable body aches or migraines can disrupt heart rhythm and to ride the pressure.

If depression in women is associated with hormonal changes during the menstrual cycle, it starts another attack in seven days before the onset of menstruation and ends one week after its completion. If depression occurred after the birth of the child, then it can not be held six months.

In addition to specific "female" Psychologists distinguish depression and depression in the elderly. Among the people who turned Diamond Jubilee with depression about twenty percent. The symptoms and the causes of this type of depression are very characteristic. It begins depression in the elderly due to retirement, absence of loved ones, or death, the emergence of a large number of geriatric diseases. Scientists have shown that the tendency to depression is inherited genetically. In some people, this tendency manifests itself only in old age.

What are the signs of depression in the elderly?
Here, everything is more complicated. What exactly can be called the signs of depression and what is simply a reaction to any difficult circumstances? Most often, depression in the elderly is manifested in the form of a sharp change in the character. The elderly man suddenly starts finding fault in everything he dissatisfied with everything, thinks only about themselves and their sores. If your grandmother or grandfather is doing anything like this, do not be angry at him and do not swear. It is a disease that must be treated by the doctor.

It is very common in today's society, and depression, which are associated with certain seasons of the year, the so-called "seasonal". If you have depression during the cold season are shown for three consecutive years, it is possible to diagnose "seasonal depression".

The symptoms and causes of depression this kind is not particularly different from other types of depression. The patient will be reduced to life, there is no interest to the surrounding reality, it seems that nothing good in life will be gone. Often these symptoms particularly clearly manifest themselves before lunch. But this type of depression, there are quite specific symptoms. It is the appearance of a wild appetite and constant craving for sleep. Usually, people suffering from seasonal depression, much get fat for the winter, because they eat lots of carbohydrate heavy foods.

You can independently, using dietary supplements (nutraceuticals) to food. Depression often causes insomnia. To sleep better and wake up refreshed in the morning, take Selank and Phenibut. 

Veroshpiron (Spironolactone)

Veroshpiron (Spironolactone)

Pharmacological group: diuretics; diuretics; potassium-sparing diuretics.
Pharmacological action: Potassium-sparing diuretics, the effect of which is due to antagonism of aldosterone.

Description

Veroshpiron is an aldosterone antagonist in the pharmaceutical industry is classified as a diuretic. The drug acts competitively inhibiting aldosterone binding to receptors, particularly in renal tubules, wherein the aldosterone participated in the potassium-sodium exchange. It causes an increase in amount of drug eluted from the body of sodium and water, while keeping potassium stocks. This differs from some other Veroshpiron diuretic drug class, such as loop diuretics such as furosemide, which can greatly enhance the excretion of sodium, potassium and water. In light of this, Veroshpiron commonly called "potassium-sparing" diuretic. It is used in medicine, in some cases, including for the treatment of high blood pressure, edema associated with congestive heart failure, hyperaldosteronism (overproduction of aldosterone) and hypokalemia (lowering potassium levels are often associated with other health interventions). Veroshpiron commonly used (off-label) professional athletes and bodybuilders for short-term correction fluid volume in the body and improve muscle definition or correction of weight before a competition in sports that require certain restrictions on the weight categories.

History
Veroshpiron was developed in the late 1950s, and the first time has been widely used in clinical medicine in the early 1960s. The drug is marketed as a diuretic, potassium is not destructive and, therefore, has a less negative impact on the electrolyte balance in the body. The drug is in many respects is considered "safe" and "soft" diuretic, compared with other products of this category, such as loop diuretics, thiazide or means. Today Spironolactone is widespread in most of the developed countries of the world. The drug is available under a dozen brands, the most famous of which is considered Aldactone by Searle Company. Also widespread drugs, including in the structure other diuretics, such as furosemide or hydrochlorothiazide Lasilacton product in Aldactazide product.

Structural Features
Spironolactone is an aldosterone antagonist and a diuretic. It has the chemical name 17-hydroxy-7alfamerkapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid y-lactone acetate. Warnings (dehydration, elevated potassium levels, mortality) Abuse of diuretics in order to improve the physique or performance is characterized by a high degree of risk. The use of diuretics without proper medical supervision can lead to life-threatening level of dehydration and electrolyte imbalance. Abuse of these drugs is associated significant risk of death. It is also important to note that during the reception of potassium-sparing diuretics such as spironolactone, usually not recommended to use potassium supplements or pharmaceutical products rich in potassium. Excessive potassium intake may cause hyperkalemia, characterized by an increased risk of arrhythmia and mortality. You can also like Ovagen.

Veroshpiron: side effects
Adverse reactions associated with the use of veroshpiron may include: gynecomastia, cramps, diarrhea, drowsiness, lethargy, headache, skin irritation, rash, confusion, fever, impotence, loss of muscle coordination, menstrual irregularities, virilization and deepening of vote. It was also shown that may contribute Veroshpiron tumors in rats. Some patients taking Veroshpiron, there is the development of breast cancer, but has not yet been established causal link with cancer veroshpiron. In addition, the compound may be antiandrogenic properties, acting weak inhibitor of the binding of androgens to the receptor and testosterone biosynthesis.

Veroshpiron application
In medicine, for the treatment of hypertension, the recommended starting dose for adults is veroshpiron from 50 mg to 100 mg per day in separate doses. Waiting for the body's response may take a maximum of two weeks. The dose is adjusted depending on the individual patient's needs. Male bodybuilders use the drug (not on purpose) To increase muscle relief or to reduce weight before weighing, often at a dose of 100 mg per day in the morning. The drug is taken for 3-5 days before the event. The drug helps to eliminate excess fluid from the body, resulting in a more pronounced muscle relief (or there is a significant decrease in body weight). Women Veroshpiron rarely used as an anti-androgen. The drug is sometimes used if the androgen level in the cycle reaches a critical point, and it is necessary to reduce the risk of virilizing symptoms. For these purposes, frequently used dosage of 25-75 mg daily for 1-2 weeks, may be sufficient to prevent the adverse effects while reducing the level of androgens (the termination of steroid therapy). Since Veroshpiron more effective to reduce endogenous levels of androgens than to inhibit the action of androgens, it certainly can not be regarded as a cure-all for the athletes who abuse steroids. Since the compound is one of the softest (Rx), diuretics, most often it is used by novice competitive athletes. Having clarified for all the consequences of its use, many are trying to achieve a stronger loss of fluid by mixing veroshpiron with thiazides or furosemide (Lasix). The purpose is to provide a strong water separation with smaller losses of potassium and calcium than using strong diuretics. For example, when mixed with the hydrochlorothiazide dose veroshpiron B100 mg are often divided into two parts, taking an equal amount of thiazides. When receiving the combination of 50 mg / 50 mg noticeable increase in excretion of water without severe side effects. potassium reabsorption in the application veroshpiron balanced of thiazides. On the other hand, Lasix (furosemide) appears even stronger complement veroshpiron. In this case veroshpiron often reduce the dose to 50 mg or 20 mg of oral added Lasix that provides fluid loss effect approximately equivalent to 40 mg Lasix tablet. Again, the decrease in the level of potassium (a side effect of Lasix) may be somewhat balanced potassium-sparing effect veroshpiron. Widely available various combinations of diuretics with support in the scientific community. It is important to note that, while Lasix Gidrodiuril and more effective for the induction of short-term loss of fluid, they also have an increased risk compared with potassium-sparing diuretics, and their use should be approached with caution.

Hypothiazid (Hydrochlorothiazide)

Pharmacological group: diuretics

Pharmacological action: thiazide diuretics medium strength. Reduces Na + reabsorption in the cortical segment of the loop of Henle, without affecting its portion extending into the renal medulla, which determines a weaker diuretic effect compared with furosemide. Blocks carbonic anhydrase in the proximal convoluted tubules, increases urinary excretion of K + (in the distal tubule Na + is exchanged for K +), hydrogen carbonates and phosphates.

Description Hydrochlorothiazide - thiazide diuretic family used in medicine for the treatment of edema and hypertension. The drug reduces reabsorption of electrolytes, thereby increasing the excretion of sodium, potassium, chloride, and especially water. Compared with other diuretics, potassium-sparing Gidrodiuril is stronger Aldakton (spironolactone), but weaker than the loop diuretic Lasix (furosemide). Although the application of this preparation potassium loss is much less pronounced than with Lasix, the user may still require the use of potassium supplements. This usually depends on the dose and duration of drug application. Again, when using the drug calcium losses can be expressed in a significant degree, but, again, they are considerably less than with Lasix. Application of diuretics has become very popular in many sports. These drugs are often used in bodybuilding for a significant loss of fluid before the competition. The winning appearance in these sports depends largely on the body expressed relief that can be achieved by receiving diuretics. Today, in these disciplines pronounced relief body is indispensable, and virtually unreachable without the use of such drugs. Diuretics are also used in many athletes competing in sports with weight restrictions. Wrestlers and boxers, for example, may use diuretics in order to carry more weight in the competition than in the control weighing. Given that checkweighing produced per day (or many hours) prior to the competition, the athlete who has lost a large amount of water due to the use of diuretics, has enough time to recover before the competition lost fluids and weight. The result may be shifted by one or two weight classes that is a significant advantage in these sports.

History
Hypothiazid was developed in the 1950s. Due to the wide spread of diseases such as high blood pressure and edema, the drug gained commercial acceptance. Hydrochlorothiazide has become the main form of treatment in the field of medicine, and remains popular today. Hydrochlorothiazide is available in virtually all developed countries, and presented to literally hundreds of different brands and generics. You can also like Noopept.

Structural Features
Hypothiazid - a diuretic and antihypertensive agent. It is a 3,4-dihydro derivative of chlorothiazide, and has a chemical designation of 6-chloro-3,4-dihydro-2H-1,2,4-benzotiadizin-7-sulfonamide 1,1-dioxide. Warnings (dehydration, death) The use of diuretics in sports to a high degree of risk. Diuretics without the requisite medical supervision can lead to life-threatening levels of dehydration and electrolyte imbalance. With the use of such drugs is associated increased risk of mortality.

Side effects of hydrochlorothiazide
Application hydrochlorothiazide can lead to electrolyte imbalance that includes sodium and potassium deficiency (increase in blood bicarbonate in significant losses of chlorine). Signs of electrolyte imbalance include dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pain, muscle spasms, cramps, decrease in the volume of urine, low blood pressure and gastrointestinal disorders. Other side effects may include loss of appetite, nausea, vomiting, diarrhea, stimulation of salivary glands, headaches, dizziness, light sensitivity, decrease in blood pressure when standing, skin irritation, impotence, visual disturbances, jaundice, pancreatitis and lung irritation. In addition, it reported some rare adverse events characterized by a hypersensitivity reactions, including skin rash, fever, shock, pulmonary edema, and shortness of breath.

The use of hydrochlorothiazide
In medicine, for the treatment of hypertension usual starting dose for adults is 25 mg once a day. The dose may be increased to 50 mg per day, and is often divided into two doses of 25 mg. Please note that daily doses greater than 50 mg is often associated with a marked decrease in the level of potassium in the blood serum. For liquid level control in the body athletes and bodybuilders typically use medication (off-label) for very short periods of time (a few days). A common practice is the use of the drug once a day after breakfast. In this case the athlete must control the level of water loss during the day, and the dose adjusted to the next day, if necessary. The usual starting dose is one tablet of 50 mg. The user must adjust the effectiveness of the drug by addition of 25 mg or 50 mg every day. It is practiced only 3-4 days until the optimal dose. The total daily dose of 100-200 mg rarely exceeds (receiving doses greater than 100 mg per day is usually not recommended in clinical setting). If the use of hydrochlorothiazide did not produce the desired effect, many bodybuilders / athletes, before moving on to more powerful (loop) drugs used extra (mild) diuretic. combination is considered to be particularly effective potassium-sparing diuretics, such as aldactone (spironolactone) and Hypothiazid that may be a bit to balance calcium and potassium loss associated with hydrochlorothiazide. This significantly reduces the dosage of each drug, and usually begins with the use of 25/25 mg gradually increasing. It is important to note that excessive use of diuretics may be potentially dangerous and can lead to too much water loss, which may contribute to the flat, "deflated" mind muscle. Thus, higher doses of diuretics does not always lead to increased clarity and muscle relief. Competitors are planning to use diuretics before the competition, it will be useful to get acquainted with their action, before applying them to this end. Otherwise, the user can properly adjust the dosage, which can be very dangerous and inefficient practice.

Furosemide (Lasix)

Pharmaceutics Group: diuretics; loop diuretics

Pharmacological action: "Loop" diuretics; It is coming quickly, strong and short diuresis. It possesses natriuretic and hlordiuretic effect, increases excretion of K +, Ca2 +, Mg2 +. Penetrating into the lumen of the tubule in the large segment of the ascending limb of Henle's loop, blocks the reabsorption of Na + and Cl-. Due to the increasing allocation of Na + occurs secondary (indirect osmotic bound water) increased excretion of water and an increase in K + secretion in the distal tubule. Simultaneously, excretion of increased Ca2 + and Mg2 +.

Description
Furosemide relates to a class of drugs known as loop diuretics. These drugs work by encouraging the body secrete fluid with potassium, sodium, [[magnesium | magnesium]], and calcium chloride. Most often, these medications are used to treat edema and high blood pressure. Like other drugs of this type, Furosemide acts by inhibiting Na-K-2CI symporter into the thick ascending loop of Henle, which is the carrier protein attracting sodium, potassium and chloride into the cell. This mode of action is not associated with the inhibition of aldosterone. Loop diuretics are among the most potent diuretics, and may have very strong effect on the fluid level and electrolytes in the body. In particular, in their use should be carefully monitored levels of potassium, and patients may require potassium supplementation medications. Without the support of appropriate levels of potassium and other electrolytes can develop serious complications from the heart. potassium overdose has less serious consequences, so it should be noted that the use of Furosemide may be especially risky without proper medical supervision.

Furosemide for slimming
Athletes and bodybuilders use diuretics for their own purposes, and only for short periods of time. Professional athletes participating in competitions with weight restrictions, can use these drugs to reduce weight due to the excretion of excess fluid. Since the weighing procedures are often held in one or several days prior to competition, athletes can significantly reduce their weight through diuretics, and return to normal as a result of rehydration within a few hours after discontinuation of the drug. It can provide them with a strong competitive advantage, allowing to compete with the more heavyweight than the dictates of their weight category. This practice "drop weight" is almost universal in these sports. Bodybuilders use diuretics when preparing for competitions. Here drugs such as furosemide, are effectively used to reduce subcutaneous fluid level, increasing the prominence of body that is so highly valued in the competitive bodybuilding.

History
Furosemide was developed in the early 1960s. Many of the initial studies was conducted diuretic in Europe mainly - in Germany and Italy. The drug proved to be quite successful, and for several years has received worldwide attention and recognition as a means to treat edema, and high blood pressure. For several years, Furosemide becoming the most popular drug in the art of medicine. Currently, almost all parts of the world, you can find one and multy-ingridient preparations, including in the structure is a diuretic. The most recognizable brand Lasix is currently marketed in the US and many other countries under the name Sanofi Aventis. It is difficult to enumerate the actual number of different brands and generic Furosemide.

How supplied
Furosemide often comes in the form of oral tablets of 20mg, 40 mg and 80 mg, and the injection solutions containing 10 mg / ml.

Warnings (dehydration, death)
Furosemide is a very powerful diuretic, use of which can lead to a significant increase in the allocation of water (diuresis) and electrolyte depletion. Abuse of diuretics such as furosemide, to improve productivity or build, has a high degree of risk. Without proper medical supervision, diuretics can lead to life-threatening levels of dehydration and electrolyte imbalance. Abuse of these drugs is associated significant risk of death.

Furosemide: side effects
Use Furosemide may be due to an imbalance of electrolytes that may include: the depletion of potassium (hypokalemia), sodium (hyponatremia), magnesium (hypomagnesemia) and calcium (hypocalcemia), and hypo-chloric alkalosis, increased blood bicarbonate level from large chloride losses. Signs of electrolyte imbalance include dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pain, muscle spasms, convulsions, decrease the amount of urine, low blood pressure and gastrointestinal disorders. Other side effects may include: pancreatitis, jaundice, anorexia, irritation of the mouth and stomach, cramps, diarrhea, constipation, nausea, vomiting, hearing loss, numbness or tingling in the extremities, dizziness, headache, blurred vision or other visual disturbances, anemia, reduction in the number of white blood cells or platelets, dermatitis, rashes, itching and sensitivity to light, low blood pressure, high blood sugar (hyperglycemia), muscle cramps, weakness, anxiety, bladder spasms, fever, blood clots and excess uric acid in the blood (hyperuricemia). Furthermore, certain rare side effects characterized as hypersensitivity reactions, including inflammation of blood vessels, renal inflammation and inflammation of blood vessels or lymph nodes (vasculitis).

Furosemide application

When used in medicine for the treatment of edema, drug is often administered orally in a single dose of 20 mg to 80 mg per day. For the treatment of hypertension, it is generally recommended to apply a dose of 80 mg per day, which is divided into two 40 mg dose used with a difference in 12 hours. Athletes and bodybuilders typically use this medication (off-label) in short periods of time (a few days) to reduce the water level in the body. Dosage and method of use are regulated depending on the desired objectives and the individual characteristics of an athlete. Oral pills are the most common form of application. The athlete, as a rule, begins to use the drug in low doses, and then, in the following days, gradually increase the dosage. The focus is on what to calculate the optimal dose and schedule to determine the best use for the participation in the show or competition. The initial dose is typically 20 to 40 mg and a maximum daily dose rarely exceed 80 mg. In order to minimize the side effects associated with this drug, it is usually not used more than 4-5 days. Note that, as Furosemide exerts such a strong influence on the levels of the electrolytes, instead of increasing the dosage is much safer, it is generally considered the addition of potassium-sparing drugs such as Aldactone (spironolactone). For this reason, a combination of a diuretic such as this, is widely produced in the form of prescription drugs. Usually they start using Aldactone 50 mg and 20 mg of furosemide, which is believed to cause about the same diuretic effect as 40 mg Furosemide, but without the same level of loss of potassium. This dose can then be adjusted to determine the optimal quantity and consumption schedule, but it rarely exceeds 100 mg / 40 mg per day. It is important to remember that these drugs may be active for hours. In this chart it can be difficult to control dehydration, so be careful and do not take diuretics, several times a day. Furosemide Injection solutions are considered to be a much more powerful form of the drug compared milligram per milligram. The solutions can be administered intramuscularly or intravenously, depending on the individual patient's needs. Intramuscular provides much more rapid action, and produces a much higher peak blood levels of the drug. Given that the action of Furosemide can be seen within a few seconds or minutes after injecting, in this method the efficiency of the drug is much easier to assess and control, at least under normal conditions. Since the effect is much more powerful injection oral administration, it is important to emphasize that while the dose should be significantly less. Intramuscular injections are the most popular among bodybuilders and athletes, and is usually taken in a dosage of 10-20 mg. Doses greater than 40 mg per day, is rarely used in bodybuilding and sports.

Availability of Furosemide (Lasix):
Furosemide is a widely available drug, and is produced and sold in many countries under various brand names. At the moment not aware of a large batch of counterfeit medication Lasix (a diuretic or any other). Do not get the drug in the form of 500 mg tablets. Such doses are used only in cases of serious illness and can be deadly to a healthy person.

Depression and Neurosis During Pregnancy

The moment a child is waiting for the happiest mother and to his father. Normally this point comes to mind parents them for life. During pregnancy, the mother feels very warm feelings for her child. But a pregnant woman happy only when she is doing well. Poor family relationships, weight gain during this period, the insults from other people and more can cause any pregnant woman in a state of depression or neurosis.

It is worth noting that this condition should be constantly monitored. Otherwise, all this has a negative impact not only on the mother's condition, but also worsen the child's well-being. Statistics show that about one quarter of pregnant women in pregnant suffer from depression and nervosa. Most often this is due to changes in hormonal cycle. These changes affect a woman's psyche. However, the fact remains. Any neurosis and depression during pregnancy can be easily treated and can be independently controlled.

If you quickly get tired, and you are constantly tormented by depression and anxiety, you've undergone neurosis and depression. The symptoms of these diseases are also insomnia, constant irritability, your indifference to everything, or guilt. Do you think that you are not wanted there, and reasoning suicide, do not think about it alone. Share your thoughts with loved ones, or psychotherapist.

All these feelings and thoughts may arise due to neglect your husband, your unwillingness to give birth, premature pregnancy. It can also happen because of your unstable financial situation or your self-doubt that you will be a good mother. There are a myriad of reasons, but they are nothing compared to the maternal feelings. You will understand when to take the first time to your child's hands.

But until then there's still time. A depression and neurosis, you do not let go. In this case, you need to start to get rid of it. The most popular way to get rid of depression and neurosis is psychotherapy. To reiterate, psychotherapy. It is not necessary to resort to antidepressants (Selank, Phenibut, Afobazole). They adversely affect the heart, liver, kidneys and other organs of your baby. Believe me, it's not worth it. Refer to the psychotherapist. It will help you forget about all the problems that brought you to this state. It will help you get rid of all suffering and attain complete peace of mind.

Normally during pregnancy to women appointed interpersonal psychotherapy or cognitive behavioral therapy. These two types of therapy can help every woman to find the right vision of all things, and fully feel the happiness of the future mothers.

There are several tips that will warn you of depression and nervosa. Always plan a pregnancy! Always take care of herself during pregnancy! Always eat only healthy food! Exercise! Think first about themselves and the baby! Most relax and think positive!

By following all these rules, you will become very happy and relaxed a pregnant woman. You will only get pleasure from this condition. Do not forget that the birth of a child - it's the most amazing event in your life. Nothing can dampen it. Think about it and take care of yourself. Your well-being - is the key to having a healthy baby.