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Trusopt eye drops 2% 5ml

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Trusopt eye drops - is a drug based on dorzolamide hydrochloride, reducing the increased intraocular pressure associated with glaucoma or intraocular hypertension. The drug has few contraindications and good tolerability.

Trusopt eye drops - antiglaucoma preparation.

The composition of the drug Trusopt includes an inhibitor of carbonic anhydrase II - dorzolamide hydrochloride. Inhibition of carbonic anhydrase in the ciliary body of the eyeball reduces the production of intraocular fluid, presumably due to a slowing down of the synthesis of bicarbonate ions with their subsequent reduction to sodium and elimination of the liquid. As a result, the intraocular pressure decreases.

Pharmacokinetics

With prolonged use, dorzolamide selectively accumulates in erythrocytes as a result of selective binding to carbonic anhydrase II, while the concentration of free dorzolamide in plasma remains extremely low.

Dorzolamide forms the only metabolite, N-desethyl-dorzolamide, which suppresses to a lesser extent than dorzolamide, the enzyme carbonic anhydrase II, and also the enzyme carbonic anhydrase I. The metabolite accumulates in red blood cells, mainly binding to carbonic anhydrase I.

Dorzolamide moderately binds to plasma proteins (about 33%).

Dorzolamide and its metabolite are excreted mainly unchanged through the kidneys. After the end of treatment, dorzolamide is washed out of the erythrocytes unevenly, i.e., very intensively at the beginning, which leads to a rapid and significant decrease in concentration, followed by a slow phase of washout with T1 / 2 for about 4 months.

Indications:

Trusopt is prescribed to reduce elevated intraocular pressure, associated and not associated with glaucoma. Trusopt is shown to patients:

  • With intraocular hypertension (increased intraocular pressure).
  • With primary open-angle glaucoma, including pseudoexfoliation glaucoma.
  • With secondary glaucoma (without the angle block of the anterior chamber of the eyes)
  • Children: for the treatment of glaucoma in children older than 1 week in monotherapy or as a supplement to the treatment with beta-blockers.

Contraindications:

  • chronic renal failure;
  • pregnancy;
  • lactation period (breastfeeding);
  • age younger than 1 week;
  • hypersensitivity to the components of the drug.
  • Application for violations of liver function

The use of Trusopt was not studied in patients with severe hepatic impairment, and therefore, use the drug in this category of patients with caution.

Special instructions:

Patients who wear contact lenses should consult a doctor before using Trusopt, since the preservative included in the product may cause eye irritation. The drug Trusopt contains as a preservative benzalkonium chloride, which can be adsorbed by contact lenses. Before using the drug, the lens must be removed; Do not wear the lens before 15 minutes after instillation. Benzalkonium chloride is capable of discoloring soft eye lenses.

Impact on the ability to drive vehicles and manage mechanisms

During the treatment with the drug Trusopt it is necessary to refrain from driving motor vehicles and practicing potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Suggested Use:

With Trusopt, the usual dose is 1 drop to the affected eye (or both eyes) in the morning, afternoon and evening.

When replacing any antiglaucoma drug with Trusopt, treatment with Trusopt should be started the day after the previous drug was discontinued.

When using Trusopt with other eye drops at the same time, they should be instilled with an interval of at least 10 minutes.

Packaging:

  • Comes in original packaging. Item is brand new and unopened.

Storage:

  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!

 

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