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Predizin 35mg 60 pills

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Predizin (Trimetazidine, Trimethazidinum) - has anti-hypoxic action. Directly affecting cardiomyocytes and neurons in the brain, improves their metabolism and function. Cytoprotective effect is due to an increase in energy potential, activation of oxidative decarboxylation and rationalization of consumption of oxygen (aerobic glycolysis and strengthen the blockade of fatty acid oxidation).

It supports myocardial contractility, prevents a decrease in intracellular ATP and phosphocreatine. In acidosis conditions normalize the functioning of membrane ion channels, prevents the accumulation of sodium and calcium ions in cardiomyocytes normalizes intracellular concentration of potassium ions.

Reduces intracellular acidosis and elevated phosphate levels caused by myocardial ischemia and reperfusion. It prevents the damaging action of free radicals, preserves the integrity of cell membranes, prevents activation of neutrophils in the zone of ischemia increases the electrical potential, reduces the yield of CK cells and the severity of ischemic damage to the myocardium.

When angina reduces the frequency of attacks and the need for the use of nitroglycerin, after 2 weeks of treatment, increases exercise tolerance, improved contractile function of the left ventricle in patients with coronary dysfunction, reduced blood pressure drops. Reduces dizziness and tinnitus. In vascular pathology eyes improves the functional activity of the retina eyes.

Directly affecting cardiomyocytes and neurons in the brain, improves their metabolism and function. Cytoprotective effect is due to an increase in energy potential, activation of oxidative decarboxylation and rationalization of consumption of oxygen (aerobic glycolysis and strengthen the blockade of fatty acid oxidation). It supports myocardial contractility and prevents depletion of intracellular ATP and phosphocreatine. In acidosis conditions normalize the functioning of ionic channels membranes, prevents the accumulation of Ca2 + and Na + in the cardiomyocytes normalizes the intracellular concentration of K +. Reduces intracellular acidosis and phosphate concentration caused by myocardial ischemia and reperfusion. It prevents the damaging action of free radicals, preserves the integrity of cell membranes, prevents activation of neutrophils in the zone of ischemia increases the electrical potential, reduces the yield of CK cells and the severity of ischemic damage to the myocardium. When reducing the frequency of attacks of angina (nitrates reduced consumption), after 2 weeks of treatment increased exercise capacity, reduced blood pressure drops. In vascular pathology eyes restores functional activity of the retina.

Indications Predizin drug:

Coronary heart disease - prevention of angina attacks (in the complex therapy);

cochleovestibular violations ischemic nature (dizziness, tinnitus, hearing loss).

Contraindications:

Hypersensitivity, chronic renal failure (creatinine clearance less than 15 ml / min), pregnancy, lactation, children's age.

Suggested Use:

Inside, 20 mg 2-3 times a day (40-60 mg / day), with meals. Modified release tablets 35 mg 2 times a day.

Packaging:

  • Comes in original packaging. Item is brand new and unopened.

Storage:

  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!

 

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