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Instruction for use: Hotemin

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Active substance Piroxicam

ņ“’ M01AC01Piroxicam

Pharmacological group

NSAIDs - Oxicams

Nosological classification (ICD-10)

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M15-M19 Osteoarthritis

M25.5 Pain in the joint

Arthralgia, Pain syndrome in musculo-articular diseases, Pain syndrome in osteoarthritis, Pain syndrome in osteoarthritis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Pain in the joints, Soreness of the joints, Soreness of joints in severe physical exertion, Painful inflammatory joint damage, Painful conditions of the musculoskeletal system, Painful joint conditions, Painful traumatic affection of joints, Pain in the musculoskeletal system, Pain in Shoulder Joints, Pain in the joints, Joint pain, Joint pain with injuries, Musculoskeletal pain, Pain with osteoarthritis, Pain in the pathology of the joints, Pain in rheumatoid arthritis, Pain in chronic degenerative bone diseases, Pain in chronic degenerative joint diseases, Bone-joint pain, Joint pain, Arthritic pain of rheumatic origin, Articular pain syndrome, Joint pain, Rheumatic pain, Rheumatic pains

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

M54 Dorsalgia

Pain in the back area, Pain in the spine, Back pain, Pain in different parts of the spine, Backache, Painful pain syndrome in the spine, Pain in the musculoskeletal system

Composition and form of release

1 ampoule with 1 ml solution for injection contains piroxicam 20 mg; in a cardboard box there are 5 ampoules.

1 g of ointment - 10 mg; in tubes of 50 grams, in a carton of 1 tube.

pharmachologic effect

Pharmacological action - anti-inflammatory, antipyretic, analgesic.

It blocks cyclooxygenase and inhibits the synthesis of PG (prostaglandins).


Inflammatory or degenerative diseases of the joints and spine, accompanied by pain, Bekhterev's disease, exacerbation of gout.


Hypersensitivity, gastric ulcer and duodenal ulcer in the stage of exacerbation, blood disorder of unclear genesis (including in the anamnesis), severe renal and / or liver dysfunction, history of bronchial asthma, childhood and adolescence (up to 14 years - ointment, up to 18 years - solution), pregnancy, breast-feeding.

pregnancy and lactation

Contraindicated in pregnancy. For the duration of treatment, breastfeeding should be discontinued.

Side effects

From the nervous system and sensory organs: dizziness, headache, drowsiness, insomnia, weakness, depression, hallucinations, blurred vision, eye irritation.

From the cardiovascular system and blood (hematopoiesis, hemostasis): anemia, thrombocytopenia, leukopenia, eosinophilia.

On the part of the digestive tract: dry mouth, stomatitis, irritation of the gastrointestinal tract, nausea, diarrhea, constipation, flatulence, bleeding gums, erosive and ulcerative lesions of the gastrointestinal tract and bleeding, violation of liver function.

From the genitourinary system: renal failure, acute interstitial nephritis.

From the side of metabolism: hyperkalemia, hypokalemia.

Allergic reactions: itching, redness of the skin, allergic swelling (face, hands), Stevens-Johnson syndrome, Lyell's syndrome, very rarely - anaphylactic reactions, bronchospasm, photosensitivity, rash.

Other: edema (mainly lower extremities in patients with impaired heart function).


It displaces other drugs from the link with the protein. Lowers the effectiveness of antihypertensive drugs. Increases the risk of hyperkalemia when combined with potassium-sparing diuretics and potassium donors and the likelihood of ulceration of the gastrointestinal tract against the background of corticosteroids and NSAIDs.

Dosing and Administration

In / m (intramuscular), with severe pain syndrome - 40 mg once a day, with moderate pain syndrome - 20 mg once a day for 1-2 days, then treatment should be carried out, if possible, with oral dosage forms. The maximum daily dose is 40 mg.

Outwardly. A strip of ointment 1-3 cm long is applied to the skin in the projection of the pain area and carefully rubbed 3-4 times a day.

Precautionary measures

Avoid contact with ointment on mucous membranes, eyes, open wounds or skin lesions.

Storage conditions

In the dark place at a temperature of 15-25 į C.

Keep out of the reach of children.


2 years.

Do not use after the expiry date printed on the package.

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