Alphagan P eye drops 0.15% 5ml

Alphagan P eye drops - is an ophthalmic drug used in the treatment of open-angle glaucoma (and a decrease in increased intraocular pressure caused by other causes), refers to selective alpha-adrenomimetics.

Brimonidine - selective alpha2-adrenomimetic, which has a stimulating effect on alpha2-adrenergic receptors. When using 0.15% drops in the drug form, the maximum decrease in intraocular pressure (IOP) is achieved after 2 hours. The hypotensive effect of brimonidine is provided by reducing the formation and increasing the outflow of intraocular fluid along the uveoscleral pathway.

Indications:

Open angle glaucoma. Increased eye pressure (both monotherapy and in combination with other drugs that reduce IOP).

Contraindications:

• hypersensitivity to brimonidine and other components of the drug;
• simultaneous therapy with MAO inhibitors;
• children under 2 years old, low body weight (up to 20 kg);
• the period of lactation.

With caution: orthostatic hypotension, heart failure, cerebrovascular diseases, resulting in cerebral circulatory insufficiency, renal failure (CC below 40 ml / min), liver failure, depression, Raynaud's syndrome, thromboangiitis obliterans, children ages 2 to 7 years.

Side effects:

The incidence of adverse events observed during the study was estimated as follows: very often (> 10%), often (> 1% and 0.1% and 0.01% and

In clinical studies of the drug Alfagan P, the following side effects were identified:

From the side of the organ of vision: very often - allergic conjunctivitis, conjunctival hyperemia, itching of the mucous membrane of the eyes and skin of the eyelids; often - a burning sensation, conjunctival follicles or follicular conjunctivitis, local allergic reactions from the eyes (including keratoconjunctivitis), blepharitis, blepharoconjunctivitis, impaired vision, cataracts, conjunctival edema, conjunctival hemorrhage, conjunctivitis, retinal lacrimation, mucous detachable from the eyes, dryness and irritation of the eye mucosa, pain, eyelid edema, redness of the eyelids, sensation of foreign body in the eyes, keratitis, eyelid lesions, photosensitivity, surface dot rathopathy, lacrimation, loss of visual fields, functional disorders of the vitreous body, vitreous hemorrhage, floating opacities in the vitreous body and decreased visual acuity; infrequently, the corneal erosion, barley;

From the side of the central nervous system: often - headache, drowsiness, insomnia, dizziness.

From the cardiovascular system: often - increased blood pressure; infrequently - a decrease in blood pressure.

On the part of the respiratory system: often - bronchitis, cough, shortness of breath; infrequently - dryness of the nasal mucosa, apnea.

From the gastrointestinal tract: often - gastrointestinal disorders - dyspepsia, dryness of the oral mucosa.

From the skin and subcutaneous fat: often - a rash.

Infectious and parasitic diseases: often - influenza-like syndrome, infectious disease (chills and respiratory infection), rhinitis, sinusitis, incl. infectious.

Laboratory indicators: often - hypercholesterolemia.

Others: often - general allergic reactions, asthenia, fatigue; infrequently - a perversion of taste.

Children noted: apnea, bradycardia, lowering blood pressure, hypothermia, muscle hypotension.

In the postmarketing period, additional reports of the following side effects were received:

From the side of the organ of vision: the frequency is unknown - iritis, dry keratoconjunctivitis, miosis;

From the side of the central nervous system: depression;

From the cardiovascular system: bradycardia, tachycardia.

From the digestive tract: nausea.

From the skin and subcutaneous fat: local skin reactions (erythema, itchy eyelids, face swelling, rash and vasodilation of the vessels of the skin of the eyelids and face).

Suggested Use:

Locally. In the conjunctival sac of the affected eye, 1 drop 3 times a day with an interval between administrations of about 8 hours.

Alfagan P can be used with other ophthalmic drugs to reduce IOP. If you use more than 2 drugs, then you need to do a 5-minute break between the installations.

Packaging:

• Comes in original packaging. Item is brand new and unopened.

Storage:

• Keep away from direct sunlight.
• Keep locked and away from children.
• Store in dry place at room temperature.
• Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!