Instruction for use: Wobenzym

ATX code L03AX Other immunostimulants

Pharmacological group

Other non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs

Other immunomodulators

Nosological classification (ICD-10)

A64 Sexually transmitted diseases, unspecified

Infectious affection of the male reproductive tract, Venereal infections, Sexually Transmitted Infections

B34 Viral infection of unspecified site

Viral respiratory tract infections, Infections viral, Viral infection

E06.3 Autoimmune thyroiditis

Autoimmune thyroiditis Hashimoto, Thyroid Bladder Lymphadenoid, Hashimoto's disease, De Kervena thyroiditis, Goiter lymphomatous, Goiter lymphocytic, Zob Hashimoto, Lymphadenoid goiter, Thyroiditis Hashimoto, Hashimoto thyroiditis, Struma Hashimoto

G35 Multiple sclerosis

Disseminated sclerosis, multiple sclerosis, Relapsing Multiple Sclerosis, Secondary progressive multiple sclerosis, Exacerbation of multiple sclerosis, Mixed forms of multiple sclerosis

H20 Iridocyclitis

recurrent iritis, sympathetic iridocyclitis, Sluggish posterior uveitis, Sluggish posterior uveitis, Posterior uveitis, the posterior segment of the eye Iridocyclitis, Iridocyclitis and other uveitis, Irit, Keratoiridotsiklit, Acute iritis, uveitis, cycle of Acute iridocyclitis, Acute non-infectious uveitis

H36.0 Diabetic retinopathy (E10-E14 + with common fourth sign .3)

Hemorrhagic diabetic retinopathy, Diabetic retinopathy, Retinal dystrophy in patients with diabetes mellitus

H44.8 Other diseases of the eyeball

Hemophthalmus, Spikes of the eye

I20 Angina [cardiac angina]

heberden disease, Angina pectoris, The attack of angina pectoris, recurrent angina, Spontaneous angina, Stable angina pectoris, angina, Angina (attack), Angina rest, Angina progressing, Angina mixed, Angina spontaneous, sable angina, Chronic stable angina, Angina Syndrome X

I21 Acute myocardial infarction

Myocardial infarction in the acute phase, Acute Myocardial Infarction, Myocardial infarction with pathologic Q wave and without, Myocardial infarction complicated by cardiogenic shock, Infarction left ventricular, Transmural myocardial infarction, Myocardial infarction netransmuralny (subendocardial), Netransmuralny myocardial infarction, Subendocardial myocardial infarction, The acute phase of myocardial infarction, Acute myocardial infarction, Sub-acute phase of myocardial infarction, Subacute phase of myocardial infarction, Thrombosis of the coronary arteries (the arteries), Threatened myocardial infarction, Myocardial infarction without Q wave

I70.2 Atherosclerosis of the arteries of the extremities

Arteriosclerosis obliterans, Arteriosclerosis of peripheral arteries, Atherosclerosis of lower limb arteries, Atherosclerosis of peripheral arteries, Atherosclerosis of the vessels of the extremities, Obliterating disease of lower extremities, Obliterating atherosclerosis, Obliterating arteriosclerosis of lower limb arteries, Obliterating arteriosclerosis of the vessels of the upper limbs, Obliterating atherosclerosis of vessels of lower extremities, Atherosclerosis of the arteries of the extremities,Arteriopathy of the extremities, Obliterating atherosclerosis of the vessels of the extremities, Obliterating arteriosclerosis

I73.8 Other specified peripheral vascular diseases

Intermittent claudication syndrome, Endarteritis obliterans, Acrocyanosis, Peripheral angiospasm, Obliterating endarteritis, Intermittent claudication, Disorders of innervation of blood vessels, Spasm of peripheral arteries, Arterial angiopathy, Venous insufficiency and its complications, Spasm of peripheral vessels, Spasm of the coronary vessels, Endarteritis, Cooling of the feet, Occlusion disorders of peripheral circulation, Occlusion of peripheral vessels

I78.9 Disease of capillaries, unspecified

Increased permeability of capillaries, Teleangiectasia, Violation of capillary permeability, Violation of capillary blood flow, Microcirculatory trophic disorder, Disorders of microcirculation

I79.2 Peripheral angiopathy in diseases classified elsewhere

Diabetic angiopathy, Angiopathy in diabetes mellitus, Diabetic arteriosclerosis, Pain in peripheral nerve lesions, Diabetic angiopathy, Diabetic microangiopathy, Diabetic vascular injury, Intermittent angioedema dysbasia, Macroangiopathy in diabetes mellitus, Microangiopathies, Microangiopathy, Microangiopathy in diabetes mellitus, Tingling sensation in the arms and legs, Sensation of coldness in the extremities, Peripheral Angiopathy, Peripheral artery disease, Sclerosis of Menkeberg, Chronic obliterating diseases of the arteries

I80 Phlebitis and thrombophlebitis

Diseases of peripheral vessels, Inflammation of superficial veins, Inflammatory diseases of veins, Deep venous thrombophlebitis, The disease of veins, Disease of the veins of the lower extremities, Diseases of peripheral vessels, Migrating phlebitis, Insufficiency of veins of lower extremities, Exacerbation of chronic thrombophlebitis, Acute thrombophlebitis,Acute thrombophlebitis of superficial veins, Periphlebitis, Periflebit surface, Superficial inflammation of veins, Surface thrombophlebitis, Surface phlebitis, Thrombophlebitis, Deep vein thrombophlebitis, Thrombophlebitis superficial, Phlebitis, Phlebitis of deep veins, Phlebitis of superficial veins, Phlebopathy, Chronic thrombophlebitis, Endophlebitis

I87.0 Postphlebitic syndrome

Postthrombotic venous insufficiency, Postthrombotic disease, Post thrombophlebitic syndrome, Post-thrombophlebitis, Post-thrombophlebitic syndrome, Postphlebitic syndrome, Post thrombotic syndrome, Postphlebitis Syndrome, Postphlebitic syndrome (stasis syndrome)

I89.0 Lymphocyte, not elsewhere classified

Venous-lymphatic insufficiency, Lymphatic edema, Lymphedema, Lymphostasis, Lymphostasis and swelling after treatment of breast cancer, Edema lymphangiectatic, Lymphatic edema, Chronic lymphostasis, Lymphodema

J01 Acute sinusitis

Inflammation of the sinuses, Inflammatory diseases of the paranasal sinuses, Purulent inflammation of the paranasal sinuses, Infectious-inflammatory diseases of ENT organs, Infection of the sinuses, Combined sinusitis, Exacerbation of sinusitis, Acute inflammation of the paranasal sinuses, Acute bacterial sinusitis, Acute sinusitis in adults, Subacute sinusitis, acute Sinusitis, sinusitis

J06 Acute upper respiratory infections of multiple and unspecified

Frequent colds viral diseases, Infections of the upper respiratory tract, Acute respiratory disease influenza character, for colds Pain, Acute colds,Cold, respiratory infection,Seasonal colds, Pain in infectious and inflammatory diseases of the upper respiratory tract, Bacterial infections of the upper respiratory tract, Bacterial respiratory infections, Viral disease of the respiratory tract, Viral respiratory tract infections, Inflammatory disease of the upper respiratory tract, Inflammation of the upper respiratory tract disease, Inflammation of the upper respiratory tract illness with difficult sputum, Inflammatory airway disease, Secondary infections with colds, Shortness of sputum in acute and chronic respiratory diseases, Upper respiratory tract infection, Infections of the upper respiratory tract, Respiratory Tract Infections, Infections of the respiratory tract and lungs, Infectious-inflammatory diseases of the upper respiratory tract, Infectious-inflammatory diseases of the upper respiratory tract and ENT-organs, Infectious-inflammatory diseases of the upper respiratory tract in children and adults, Infectious-inflammatory diseases of the upper respiratory tract, Infectious inflammation of the airways,respiratory infection, Qatar upper respiratory tract, Catarrh of the upper respiratory tract, Catarrhal disease of the upper respiratory tract, Catarrhal symptoms of the upper respiratory tract, Coughing with a cold, SARS, ARI, ARI with rhinitis phenomena, Acute respiratory infection, Acute infectious and inflammatory disease of the upper respiratory tract, Acute respiratory disease, Sore throat or nose, Respiratory viral infections, Respiratory diseases, Respiratory infections, Recurrent respiratory infections, Secondary infection with influenza, cold in the chest, Feverish condition with flu usitis, acute sinusitis, genyantritis, purulent sinusitis

J18 Pneumonia without specifying the pathogen

Alveolar pneumonia, Community-acquired pneumonia is atypical, Community-acquired pneumonia nepnevmokokkovaya, Pneumonia, Inflammation of the lower respiratory tract, Inflammatory disease of the lungs, lobar pneumonia, Infections of the respiratory tract and lungs, Infections of the lower respiratory tract, Cough in inflammatory diseases of the lung and bronchus, lobar pneumonia, nosocomial pneumonia, Exacerbation of chronic pneumonia, Acute community-acquired pneumonia, Acute pneumonia, lobular pneumonia, Pneumonia abscessed, bacterial Pneumonia, lobar pneumonia, Pneumonia alopecia, Pneumonia with obstruction of sputum discharge, Pneumonia in AIDS patients, Pneumonia in Children, Septic pneumonia, Chronic obstructive pneumonia, Chronic pneumonia, Lymphoid interstitial pneumonia

J22 Acute respiratory infection of lower respiratory tract, unspecified

Bacterial respiratory disease, Bacterial infections of the lower respiratory tract, Bacterial infections of the respiratory system, Viral respiratory disease, Viral respiratory tract infections, Inflammatory respiratory diseases, Difficult sputum separation in acute and chronic respiratory diseases, Respiratory tract infections, Respiratory and lung infections, Lower respiratory tract infections, Infections of the lower respiratory tract, Infectious inflammation of the respiratory tract, Infectious diseases of the respiratory tract, Infectious diseases of the lungs, Infectious diseases of the respiratory system, Respiratory tract infection, Cough for colds, Pulmonary infection, Acute respiratory tract infection, Acute respiratory viral infection, Acute inflammatory airway disease, Acute respiratory disease, Respiratory infection, Respiratory and viral infections, Respiratory syncytial viral infection in young children, Respiratory diseases, Respiratory infections

J32 Chronic sinusitis

Allergic rhinosinusopathy, purulent sinusitis, Catarrh nasopharyngeal area, Catarrh of the sinuses, Exacerbation of sinusitis, chronic Sinusitis

J40 Bronchitis, not specified as acute or chronic

wheeze bronchitis, Allergic bronchitis, Bronchitis asthma, Rinotraheobronhit, Asthmatic bronchitis, Bacterial bronchitis, Bronchitis, Bronchitis smoker, Inflammation of the lower respiratory tract, bronchi disease, Qatar smoker, smokers Cough, Cough in inflammatory diseases of the lung and bronchus, Violation of bronchial secretions, Violation of the functions of the bronchi, Acute bronchitis, Subacute bronchitis, tracheobronchitis, Chronic lung disease

K66.0 Peritoneal adhesions

K73.9 Chronic hepatitis, unspecified

Chronic hepatitis, Chronic hepatitis with signs of cholestasis, Inflammatory liver disease, Infection of the liver, Chronic reactive hepatitis, Chronic inflammatory liver disease, Hepatitis chronic

K76.9 Liver disease, unspecified

Change in liver function in heart failure, Restoration of impaired liver function, Severe liver function disorders, Hepatitis, Hepatosis, Hepatopathy, Liver dysfunction, Diseases of the liver, Impaired liver function, Dysfunction of the liver, Infringements of function of a liver of an inflammatory etiology, Functional liver failure, Functional disorders of the liver, Chronic liver disease, Chronic diffuse liver disease, Enterogenic diseases of the gallbladder and liver

K85 Acute pancreatitis

Acute pancreatitis, Pancreatitis, Pancreatitis hemorrhagic, Pancreatitis acute, Sepsis pancreatogenic, Acute necrotic pancreatitis, Pancreatitis edematous

K86.1 Other chronic pancreatitis

Chronic pancreatitis, recurrent pancreatitis, chronic Pancreatitis, Exacerbation of chronic pancreatitis, Pancreatitis with exocrine insufficiency

L20 Atopic dermatitis

Itchy atopic eczema, Common neurodermatitis, Allergic skin diseases, Allergic skin diseases of non-infectious etiology, Allergic skin diseases of non-microbial etiology, Allergic skin diseases, Allergic skin lesions, Allergic manifestations on the skin, Allergic dermatitis, Allergic diathesis, Allergic itching dermatosis, Allergic Skin Disease, Allergic skin irritation, Dermatitis allergic, Atopic dermatitis, Dermatosis allergic, Diathesis exudative, Skin Allergic Disease, Skin allergic reaction to medicinal and chemical preparations, Skin reaction to medication, Skin and allergic disease, Acute eczema, Chronic atopic dermatitis, Exudative diathesis, Itching allergic dermatosis

L70 Acne

Acne nodulocystica, Acne, Comedone acne, Acne Treatment, Papulous pustular acne, Papulopustulicular acne, Papulo-pustular acne, Acne, Acne Disease, Acne, Acne vulgaris, Nodular-cystic acne, Nodular-cystic acne

M02 Reactive arthropathy

Reactive arthritis

M06.9 Other specified rheumatoid arthritis

Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism

M08 Juvenile [juvenile] Arthritis

Juvenile arthritis, Juvenile chronic polyarthritis, Juvenile chronic arthritis, Juvenile rheumatoid arthritis, Arthritis juvenile chronic

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

N12 Tubulointerstitial nephritis not specified as acute or chronic

Infections of the kidneys, Tubulointerstitial nephritis, Uncomplicated pyelonephritis, Interstitial nephritis, Tubular Nephritis, Pyelitis, Pyelonephritis, Pyelocystitis, Postoperative kidney infection, Chronic inflammation of the kidneys

N30 Cystitis

urethrocystitis, recurrent cystitis, fibrous cystitis, cystopyelitis, Exacerbation of chronic cystitis, Acute bacterial cystitis

N39.0 Urinary tract infection without established localization

Fungal infections of the urinary tract, Asymptomatic bacteriuria, Bacterial infections of the urinary tract, Bacterial infections of the genitourinary system, Bacteriuria, Bacteriuria asymptomatic, Bacteriuria chronic latent,Asymptomatic bacteriuria, Asymptomatic massive bacteriuria,Inflammatory urinary tract disease, Inflammatory urinary tract disease,Inflammatory diseases of the bladder and urinary tract, Inflammatory diseases of the urinary system, Inflammatory diseases of the urinary tract, Inflammatory diseases of the urogenital system, Fungal diseases of the urogenital tract, Urinary Tract Infections,Urinary Tract Infections, Infections of the urinary system, Urinary tract infections, Urinary Tract Infections, Urinary tract infections caused by enterococci or mixed flora, Urinary tract infections uncomplicated, Urinary tract infections complicated, Infections of the urogenital system, Infections urogenital, Infectious diseases of the urinary tract, Urinary Tract Infection, Urinary tract infection, Urinary system infection, Urinary tract infection, Urinary tract infection,Infection of the urogenital tract, Uncomplicated urinary tract infections, Uncomplicated infections of the genitourinary system, Exacerbation of chronic urinary tract infection, Retrograde kidney infection, Recurrent urinary tract infections, Recurrent urinary tract infections,Recurrent infectious diseases of the urinary tract, Mixed urethral infections, Urogenital infection, Urogenital Infectious-Inflammatory Disease, Urogenital mycoplasmosis, Urologic disease of infectious etiology, Chronic urinary tract infection, Chronic inflammatory diseases of the pelvic organs, Chronic urinary tract infections, Chronic infectious diseases of the urinary system

N41.0 Acute prostatitis

Acute bacterial prostatitis, Urethroprostatitis, Chlamydial prostatitis

N41.1 Chronic prostatitis

Recurrent prostatitis, Chronic bacterial prostatitis, Chronic abacterial prostatitis, Chronic bacterial prostatitis, Chlamydial prostatitis, Exacerbation of chronic prostatitis, Chronic abacterial prostatitis

N60.1 Diffuse cystic mastopathy

Benign cystic change in mammary glands, Cystic fibrosis mastopathy, Fibrous-cystic mastopathy, Pre-cancerous condition of mammary glands, Benign mammary gland disease, Benign breast tumor

N70 Salpingitis and oophoritis

Adnexitis, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Oophoritis, Acute adnexitis, Salpingitis, Salpingo-oophoritis, Chronic inflammatory diseases of the ovaries, Inflammation of the ovaries

N99.4 Postoperative adhesions in the pelvis

Adhesive disease

O26.9 Pregnancy-related condition, unspecified

Gestosis, Pregnancy Pregnancy, Gestosis, Psychological problems in pregnancy, Stretch marks after pregnancy, Condition of hair after pregnancy, Condition of nails after pregnancy, Convulsions with gestosis

R45.7 Condition of emotional shock and stress, unspecified

The impact of stress factors, Exposure to extreme situations, Neuropsychic stresses, Professional stress, Psychoemotional overload and stress, Psychoemotional stress, Stressful condition, Stress, Stress loading, Stressful condition, Stressful situations, Stress conditions, Stress of everyday life, Chronic stress, Chronic stress, Long-term emotional stress, Psychological stress in air flights,Psychoemotional stress in stressful situations

R60.0 Localized swelling

Allergic laryngeal edema, Local swelling, local edema, localized swelling, Swelling of the lower extremities, Swelling caused by inflammation of the tendon sheath, The swelling after dental surgery, Swelling of the mucosa of the nasopharynx, Swelling of traumatic origin, Traumatic edema, Swelling with injuries, Post-traumatic swelling, Post-traumatic edema, Post-traumatic soft tissue edema, Traumatic edema, Edema oral

R68.8.0 * Inflammatory syndrome

Painful syndrome of inflammatory genesis, Pain syndrome with inflammation of non-rheumatic nature, Pain syndrome with inflammatory lesions of the peripheral nervous system, Painful inflammation of the shoulder joint, Painful inflammation after trauma or surgery, Painful inflammation after surgery, Painful hemorrhoids, Inflammation of the tympanic membrane, Inflammation of the larynx, Inflammation of the gums, Inflammation of cellulose, Inflammation of lymph nodes, Tonsillitis, Inflammation of muscles, Inflammation of soft tissues, Inflammation of the mouth, Inflammation after surgery and trauma, Inflammation after orthopedic surgery, Inflammation after trauma, Inflammation in rheumatoid arthritis, Inflammation of the middle ear, Inflammatory gum disease, Inflammatory diseases of the eyelids, Inflammatory eye diseases, Inflammatory swelling of soft tissues, Inflammatory processes, Inflammatory processes after surgical interventions, Inflammatory process, Inflammatory Syndrome, Inflammatory syndrome of non-rheumatic origin, Inflammatory syndrome after surgery, Purulent infections, Infringements of function of a liver of an inflammatory etiology, Acute inflammation of the musculoskeletal tissue, Pre-inflammatory soft tissue inflammation

T14.0 Surface injury of unspecified body region

Abrasions, Scratch, Skin Wounds, Wounds of soft tissues, Hematoma, Hematoma of traumatic origin, Hematomas, Hematomas of muscles, Hematomas of soft tissues, Healing of the skin, Bruise, Bruising due to sprains and bruises, Microtrauma, External bruises, Small combing, Superficial hematoma, Superficial damage to the skin and mucous membranes, Subcutaneous hematoma, Post-traumatic hematoma, Post-traumatic disturbance of microcirculation, Skinness of the skin, Traumatic plexus lesions, Injury, Contusion of soft tissues, Joint bruise, Traumatic bruises, Traumatic injury, Primary treatment of surface contaminated wounds, Abrasion, Bruise

T14.1 Open wound of unspecified body region

Secondary healing processes, Sluggishly granulating wounds, Sluggishly healing wounds, Sluggish wounds, Deep Wounds, Purulent wound, Granulating wounds, Prolonged non-healing wound, Long-lasting non-healing wound and ulcer, Long-lasting non-healing soft tissue wound, Healing of wounds, Wound healing, Capillary bleeding from superficial wounds, Bleeding wound, Radiation Wounds, Slowly epithelializing wounds, Minor cuts, Suppurated wounds, Violation of wound healing processes, Breach of skin integrity, Violations of the integrity of the skin, Violations of the integrity of the skin, Small cuts, Uninfected wounds, Uncomplicated wounds, Operating wound, Primary treatment of surface contaminated wounds, Primary wound treatment,Primary-delayed treatment of wounds, Poorly cicatrizing wound, Poor wound healing, Bad wound, Superficial injury, Superficial wound with mild exudation,Wound, The wound is large, Bite wound, Wound process, Wounds, Wound healing wounds, Stump Wounds,Wounds for gunshot, Wounds with deep cavities,Difficult healing wounds, Difficult wounds, Chronic Wounds

T14.2 Fracture in unspecified area of body

Internal fixation of bone fracture, Acute period after fractures of bones, Edema after interventions for fractures, Fracture, Fractures of bones, Reposition of bone fragments in fractures, Traumatic bone injuries, Traumatic bone injury,Injuries of the osteoarticular system, Injuries to bone tissue

T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of the joint of the unspecified area of the body

Painful stretching of muscles, Pain and inflammation in tension, Dislocation of dislocation, Degenerative changes in the ligamentous apparatus, Edema due to sprains and bruises, Edema after interventions for sprains, Damage and rupture of ligaments, The musculoskeletal system is damaged, Damage to ligaments, Damage to the joints, Ligament ruptures, Tendon tendons,Ruptures of the tendons of muscles,Stretching, Crick, Stretching of the muscle, Sprain, Tension of the tendons, Extensions,Stretch muscles, Sprains, Tension of the tendons, Injury of the musculoskeletal system, Injuries to the joints, Injuries of capsule-articular tissues, Injuries of the osteoarticular system, Injuries to ligamentsInjuries to the joints, Joint wounds, Stretching of the ligamentous apparatus, Habitual stretching and tearing

T14.9 Injury unspecified

Pain syndrome after trauma, Pain syndrome with injuries, Pain syndrome with trauma and after surgery, Pain in case of injury, Pain of a traumatic nature, Joint pain with injuries, Postoperative and post-traumatic pain, Pain in case of injury, Pain of a traumatic origin, Severe pain syndrome of traumatic origin, Deep tissue damage, Deep scratches on the trunk, Closed injury, Minor Household Injuries, Minor skin damage, Violations of the integrity of soft tissues, Uncomplicated trauma, Extensive traumatic injury, Acute pain syndrome of traumatic origin, Edema with trauma, Postponed sports injuries, Post-traumatic pain, Soft tissue injuries, Joint wounds, Sports injuries, Injury, Traumatic pain, Traumatic pains, Traumatic infiltrate,Injuries to sports

T30 Thermal and chemical burns, unspecified

Pain syndrome with burns, Pain in burns, Pain with burns, Sluggishly healing post-burn wounds, Deep burns with a wet scab, Deep burns with abundant compartments, Deep burn, Laser burn, Burn, Burning of the rectum and perineum, Burn with mild exudation, Burn disease, Burn injury, Superficial burn, Superficial burn of I and II degree, Superficial skin burns, After-burn trophic ulcer and wound, Post-burn complication, Loss of fluid during burns, Sepsis burn, Thermal burns, Thermal skin lesions, Thermal burn, Trophic after-burn ulcers, Chemical burn, Surgical burn

T79.3 Post-traumatic wound infection, not elsewhere classified

Inflammation after surgery and trauma, Inflammation after trauma, Secondary infection of skin and mucous membrane damage, Deep Wounds, Purulent wound, Purulent necrotic phase of wound process, Purulent-septic diseases, Purulent wounds, Purulent wounds with the presence of deep cavities, Granulating wounds of small size, Disinfection of purulent wounds, Wound Infections, Infections wound, Infection of wounds, Infected and non-healing wound, Infected postoperative wound, Infected wound, Infected Skin Wounds, Infected burns, Infected Wounds, Suppurating postoperative wounds, Extensive purulent-necrotic process of soft tissues, Burn infections, Burn infection, Perioperative infection, Poorly healing infected wound, Postoperative and purulent-septic wound, Postoperative wound infection, Wound infection, Wound botulism, Wound infections, Wounds of purulent, Wounds infected, Reinfection of granulating wounds, Sepsis posttraumatic

T88.9 Complication of surgical and medical care, unspecified

Pain in the postoperative period, Pain in the postoperative period after orthopedic surgery, Pain syndrome after diagnostic procedures, Pain after surgery Diagnostic, Pain after surgery, Pain after orthopedic surgery, Pain after the removal of hemorrhoids, Pain in the application of excimer laser, Pain with injuries and after surgical interventions, Pain syndromes in the dental practice, Painful diagnostic intervention, Painful diagnostic manipulations, Painful instrumental diagnostic procedures, Painful instrumental manipulation, Painful treatments, Painful manipulations, Painful dressings, Painful therapeutic interventions, Pain in the area of the surgical wound, Pain in the postoperative period, Pain after diagnostic procedures, Pain after orthopedic surgery, Pain during diagnostic procedures, Pain during therapeutic procedures, Pain in orthopedics, The pain in the postoperative period, Pain after diagnostic procedures, The pain after sclerotherapy, The pain after dental surgery, postoperative Pain, Pain postoperative and posttraumatic, The pain of tooth extraction, Inflammation after surgery or injury, Inflammation after orthopedic surgery, Inflammation after surgery, The inflammatory syndrome after surgery, Festering postoperative fistula, Operating wound, Complications after tooth extraction

Y42.4 Oral contraceptives

Y42.5 Other estrogens and progestogens

Z100 * CLASS XXII Surgical practice

Abdominal surgery, adenomectomy, Amputation, Coronary angioplasty, Angioplasty of the carotid arteries, Antiseptic skin treatment for wounds, Antiseptic Hand, Appendectomy, atherectomy, Balloon coronary angioplasty, Vaginal hysterectomy, The coronary bypass, Interventions in the vagina and cervix, Interventions on the bladder, Intervention in the mouth, Restoration and reconstructive surgery, Hand hygiene of medical personnel, Gynecologic surgery, Gynecological intervention, Gynecological surgery, Hypovolemic shock during operations, Disinfection of purulent wounds, Disinfection of wounds edges, Diagnostic intervention, Diagnostic procedures, Cervical Diathermocoagulation, Long-surgery, Replacing the fistula catheters, Infection in orthopedic surgery, Artificial heart valve, cystectomy, Short-term outpatient surgery, Short-term operation, Short surgical procedures, Krikotireotomiya, Blood loss during surgery, Bleeding during surgery and in the postoperative period, Kuldotsentez, laser photocoagulation, laser coagulation, retinal laser coagulation, Laparoscopy, Laparoscopy in Gynecology, CSF fistula, Small gynecological operations, Small surgical procedures, Mastectomy and subsequent plastic, mediastinotomy, Microsurgical operations on the ear, Mukogingivalnye operation, suturing, Minor surgery, neurosurgical operation, Immobilization of the eyeball in ophthalmic surgery, testectomy, pancreatectomy, Perikardektomiya, The period of rehabilitation after surgery, The period of, convalescence after surgery, Percutaneous transluminal coronary angioplasty, Pleural thoracentesis, Pneumonia postoperative and posttraumatic, Preparation for surgical procedures, Preparation for surgery, Preparation of the surgeon's hands before surgery, Preparation of the colon for surgical procedures, Postoperative aspiration pneumonia in neurosurgical and thoracic surgery, Postoperative nausea, Postoperative bleeding, postoperative granuloma, postoperative shock, The early postoperative period, myocardial revascularization, Radiectomy, gastric Resection, bowel resection, uterine Resection, liver Resection, enterectomy, Resection of part of the stomach, Reocclusion of the operated vessel, Bonding tissues during surgical procedures, Removal of sutures, Condition after eye surgery, Condition after surgery, Condition after surgery in the nasal cavity, Condition after gastrectomy, Status after resection of the small intestine, Condition after tonsillectomy, Condition after removal of the duodenum, Condition after phlebectomy, Vascular surgery, Splenectomy, Sterilization of surgical instruments, Sterilization of surgical instruments, sternotomy, Dental surgery, Dental intervention in periodontal tissues, strumectomy, Tonsillectomy, Thoracic surgery, total gastrectomy, Transdermal intravascular coronary angioplasty, Transurethral resection, Turbinektomiya, Removal of a tooth, cataract surgery, Removal of cysts, tonsillectomy, Removal of fibroids, Removing the mobile primary teeth, Removing polyps, Removing broken tooth, Removal of the uterus body, Removal of sutures, Urethrotomy, Fistula likvoroprovodyaschih ways, Frontoetmoidogaymorotomiya, Surgical infection, Surgical treatment of chronic limb ulcersm, Surgery, The surgery in the anal area, The surgery on the colon, Surgical practice, The surgical procedure, Surgical interventions, Surgery on the gastrointestinal tract, Surgical procedures on the urinary tract, Surgical procedures on the urinary system, Surgical intervention of the genitourinary system, Surgical procedures on the heart, Surgical manipulation, surgery, Surgery on the veins, Surgical intervention, Vascular surgery, Surgical treatment of thrombosis, cholecystectomy, Partial gastric resection, transabdominal hysterectomy, Percutaneous transluminal coronary angioplasty, Percutaneous transluminal angioplasty, Coronary artery bypass, tooth Extirpation, Extirpation of milk teeth, pulpectomy, pulsative cardiopulmonary bypass, tooth Extraction, teeth Extraction, cataract extraction, Electrocoagulation, endourological intervention, episiotomy, Etmoidotomiya, Complications after tooth extraction

Z51.0 Course of Radiotherapy

Supplement to external radiation therapy, Local X-ray irradiation, Radiation therapy, Brain edema associated with radiation therapy, Lesion in radiation therapy, Radiotherapy

Z51.1 Chemotherapy for neoplasm

Cystitis hemorrhagic, caused by cytostatics, Urotoxicity of cytostatics

Z98.8 Other specified poslehirurgicheskie state

Suppurative complications in the postoperative period, Suppurative complications of surgery, Postoperative liver dysfunction, Postoperative vomiting, Postoperative complications, The postoperative period, The early postoperative period

Composition

Tablets are enteric, coated with a coating.

active substances:

pancreatin 300 prot. ED (100 mg)

papain 90 FIP ED (18 mg)

rutoside trihydrate 50 mg

bromelain 225 FIP ED (45 mg)

trypsin 360 FIP ED (12 mg)

lipase 34 FIP ED (10 mg)

amylase 50 FIP ED (10 mg)

chymotrypsin 300 FIP ED (0.75 mg)

auxiliary substances: lactose monohydrate - 149 mg; pregelatinized starch - 31.3 mg; magnesium stearate - 6 mg; stearic acid - 6 mg; silicon dioxide colloidal anhydrous - 3 mg; talc - 1.5 mg

shell: membrane film (methacrylic acid-methyl methacrylate copolymer (1: 1) - 11.9 mg, sodium lauryl sulfate - 0.04 mg) - 11.9 mg; talc - 4.23 mg; macrogol 6000 - 0.67 mg; triethyl citrate 1.2 mg; stearic acid - 6 mg; color coating (hypromellose 3.2 mg, hydroxypropyl cellulose - 3.83 mg, MCC 1.6 mg, glycerol 0.64 mg, talc 1.92 mg, titanium dioxide 0.38 mg, dye 4R E124) 0.38 mg, yellow-orange colorant S (E110) 0.83 mg) 12.8 mg

Description of dosage form

Round, biconvex tablets with a smooth surface, from red-orange to red, with a characteristic odor.

pharmachologic effect

Pharmacological action - metabolic, enzymatic.

Pharmacodynamics

The drug WOBENZYM is a combination of natural enzymes of plant and animal origin. Entering the body, the enzymes are absorbed in the small intestine by resorption of intact molecules and, when bound to the transport proteins of the blood, enter the bloodstream. Subsequently, enzymes migrating along the vascular bed and accumulating in the zone of the pathological process have immunomodulatory, anti-inflammatory, fibrinolytic, anti-edema, antiplatelet and secondary analgesic effects.

The drug WOBENZYM has a positive effect on the course of the inflammatory process, it limits the pathological manifestations of autoimmune and immunocomplex processes, positively influences the immunological reactivity of the organism. It stimulates and regulates the level of functional activity of monocyte-macrophages, natural killer cells, stimulates antitumor immunity, cytotoxic T-lymphocytes, and phagocytic activity of cells.

Under the influence of the drug WOBENZYM, the number of circulating immune complexes decreases and the membrane deposits of immune complexes from tissues are removed.

The drug WOBENZYM reduces the infiltration of interstitium by plasma cells. Increases the elimination of protein detritus and fibrin deposits in the inflammation zone, accelerates the lysis of toxic metabolic products and necrotic tissues.

The drug WOBENZYM normalizes the permeability of the walls of the vessels, promotes faster resorption of hematomas and edema.

The drug WOBENZYM reduces the concentration of thromboxane and the aggregation of platelets. It regulates the adhesion of blood cells, increases the ability of erythrocytes to change their shape, regulating their plasticity, normalizes the number of normal discocytes and reduces the total number of activated platelet forms, normalizes blood viscosity, reduces the total number of microaggregates, improving microcirculation and rheological properties of blood, as well as supplying tissues with oxygen and nutrients.

The drug WOBENZYM reduces the severity of side effects associated with taking hormonal drugs (including hypercoagulable).

The drug WOBENZYM normalizes lipid metabolism, reduces the synthesis of endogenous Xc, increases the level of HDL, reduces the level of atherogenic lipids, improves the absorption of polyunsaturated fatty acids.

The drug WOBENZYM increases the concentration of antibiotics in the blood plasma and inflammation focus, thus, increasing the effectiveness of their application. At the same time, enzymes reduce unwanted side effects of antibiotic therapy (dysbacteriosis), by improving the environment.

The drug WOBENZYM regulates the mechanisms of nonspecific defense (the production of interferons), thereby demonstrating antiviral and antimicrobial effects.

Indications

It is used in the complex therapy of the following diseases:

angiology - thrombophlebitis, postthrombophlebitis and acute thrombophlebitis of superficial veins, endarteritis and obliterating atherosclerosis of arteries of lower limbs, prevention of recurrent phlebitis, lymphatic edema;

urology - cystitis, cystopyelitis, prostatitis, sexually transmitted infections;

gynecology - chronic infections of the genitals, adnexitis, gestosis, mastopathy;

cardiology - angina pectoris, subacute stage of myocardial infarction (to improve the rheological properties of the blood);

pulmonology - sinusitis, bronchitis, pneumonia;

gastroenterology - pancreatitis, hepatitis;

nephrology - pyelonephritis, glomerulonephritis;

endocrinology - diabetic angiopathy, diabetic retinopathy, autoimmune thyroiditis;

rheumatology - rheumatoid arthritis, reactive arthritis, Bechterew's disease;

dermatology - atopic dermatitis, acne;

surgery - prevention and treatment of postoperative complications (inflammation, thrombosis, edema), adhesions, posttraumatic and lymphatic edema, plastic and reconstructive surgeries;

Traumatology - injuries, fractures, distortions, ligamentous apparatus injuries, bruises, chronic posttraumatic processes, inflammations of soft tissues, burns, injuries in sports medicine;

neurology - multiple sclerosis;

pediatrics - atopic dermatitis, infectious and inflammatory diseases of the respiratory tract (inflammation of the upper and lower respiratory tract, pneumonia), juvenile rheumatoid arthritis, prevention and treatment of postoperative complications (suppuration and poor wound healing, adhesion formation, local edema);

ophthalmology - uveitis, iridocyclitis, hemophthalmus, diabetic retinopathy, ophthalmic surgery.

Prevention of disorders of microcirculation, post-stress disorders, as well as failure of adaptation mechanisms.

Prevention of side effects of HRT, hormonal contraception. When surgical interventions to prevent infections and adhesions.

The drug WOBENZYM is recommended for the prevention of infectious complications and the improvement of the quality of life during chemo- or radiotherapy.

Prevention of the development of viral infections and their complications.

Contraindications

individual intolerance of individual components of the drug;

diseases associated with an increased likelihood of bleeding (hemophilia, thrombocytopenia);

conducting hemodialysis;

children under 5 years.

pregnancy and lactation

Pregnancy and lactation are not a contraindication for the use of the drug, however pregnant women should take the drug WOBENZYM under the supervision of a doctor.

Side effects

The drug WOBENZYM is well tolerated by patients. In most cases of side effects, withdrawal syndrome, addiction was not observed even with long-term treatment with high doses. In some cases, slight changes in the consistency and smell of stool, skin rashes in the form of urticaria, which occur with a decrease in the dose of the drug or withdrawal.

If other adverse reactions not noted in the description occur, it is recommended that you stop taking the drug and consult a doctor.

Interaction

When the drug is taken with other medications, cases of incompatibility are not described.

Dosing and Administration

Inside, at least 30 minutes before meals, without chewing, washing with water (200 ml).

Adults

Depending on the activity and severity of the disease, the drug WOBENZYM is taken in a dose of 3 to 10 tablets. 3 times a day. In the first 3 days of taking the drug, the recommended dose is 3 tablets. 3 times a day.

With an average disease activity, the drug VABENZIM is prescribed in a dose of 5-7 tablets. 3 times a day for 2 weeks. In the future, the dose of WOBENZYM should be reduced to 3-5 tablets. 3 times a day, the course - 2 weeks.

When the activity of the disease is high, the drug WOBENZYM is prescribed in a dose of 7-10 tablets. 3 times a day for 2-3 weeks. In the future, the dose of WOBENZYM is reduced to 5 tablets. 3 times a day, the course - 2-3 months.

In chronic long-term diseases, the drug WOBENZYM can be used according to the indications for courses from 3 to 6 months and more.

To increase the effectiveness of antibiotics and prevent dysbacteriosis, the drug WOBENZYM should be used throughout the course of antibiotic therapy at a dose of 5 tablets. 3 times a day. After stopping the course of antibiotics to restore the microflora (biocenosis) of the intestine, the drug WOBENZYM should be assigned to 3 tablets. 3 times a day for 2 weeks.

As a cover therapy during chemotherapy and radiation therapy, the drug WOBENZYM should be used in a dose of 5 tablets. 3 times a day before the completion of chemotherapy and radiation therapy; to prevent infectious complications, to improve the tolerability of basic therapy and to improve the quality of life.

When using the drug WOBENZYM with a preventive purpose, the dose of the drug is 3 tablets. 3 times a day, a course of 1.5 months with a repeat 2-3 times a year.

Children

Children from 5 to 12 years - 6 kg of child weight 1 table. per day; from 12 years - according to the scheme for adults.

Dosage and duration of treatment depend on the severity of the disease and are determined by the doctor.

Overdose

Cases of drug overdose are unknown.

special instructions

In the case of infectious processes, the drug WOBENZYM does not replace antibiotics, but increases their effectiveness, increasing the concentration in the blood plasma and the focus of inflammation.

It should be borne in mind that at the very beginning of taking the drug the symptoms of the disease can worsen, in such cases, treatment should not be interrupted, but a temporary reduction in the dose of the drug is recommended.

The drug is not doping.

Influence on the ability to drive vehicles and mechanisms. The drug does not adversely affect the ability to drive vehicles and perform work that requires a high rate of mental and physical reactions.

Form of issue

Tablets are enteric, coated. For 20 tablets. in PVC / PE / PVDC / aluminum blister. By 2, 5 or 10 bl. in a pack of cardboard.

For 800 tablets. in a vial of HDPE. On 1 ôë. in a pack of cardboard.

Conditions of leave from pharmacies

Without recipe.

storage Conditions

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life of Wobenzym

2 years.

Do not use after the expiry date printed on the package.