Instruction for use: Vero-Loperamid

Active substance Loperamide

ATX code A07DA03 Loperamide

Pharmacological group

Antidiarrheal drugs

Composition and release form

1 tablet contains loperamide 0,002 g; in a blister strip packaging 10 pcs., in a cardboard bundle 2 packs.

pharmachologic effect

Pharmacological action - antidiarrheal.

It interacts with the opiate receptors of the longitudinal and annular muscles of the intestinal wall and inhibits the release of acetylcholine and PG. Slows peristalsis and increases the time of passage of intestinal contents. Increases the tone of the anal sphincter, helps to retain the feces and reduce the urge to defecate.

Pharmacodynamics

It lowers the motility and tone of the intestinal smooth muscle, spasms the anal sphincter, inhibits the secretion of fluid and electrolytes into the intestinal lumen and / or stimulates the absorption of salts and water from the intestine. The action comes quickly and lasts 4-6 hours.

Indications

Diarrhea (acute and chronic), stool regulation in patients with ileostomy.

Contraindications

Hypersensitivity, intestinal obstruction, acute ulcerative or pseudomembranous colitis, childhood (up to 5 years), pregnancy (I term), breastfeeding.

pregnancy and lactation

Contraindicated in the first trimester of pregnancy. At the time of treatment should stop breastfeeding.

Side effects

From the nervous system and sensory organs: dizziness, drowsiness, fatigue.

On the part of the digestive tract: constipation, nausea, intestinal obstruction, toxic megacolon.

Dosage and administration

Inside Acute diarrhea: adults - 0.004 g, then 0.002 g after each bowel movement with liquid stools; children over 5 years old - 0.002 g, then 0.002 g after each bowel movement act with a liquid stool.

Chronic diarrhea: adults - 0.004 g, then 0.002 g 1–6 times a day; children over 5 years old - 0.002 g 1–5 times a day.

Precautionary measures

With caution prescribed for dehydration, infectious diarrhea, abnormal liver function, elderly (risk of loss of fluid and electrolytes).

special instructions

In the absence of the effect of the drug for 2 days, it is necessary to clarify the diagnosis and exclude infectious genesis of diarrhea.

Storage conditions

Under normal conditions.

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiration date printed on the package.