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Instruction for use: Sodium nucleate

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Trade name of the drug Sodium nucleinate

The Latin name of the substance Sodium nucleate

Natrii nucleinas (genus. Natrii nucleinatis)

Pharmacological group:

Other immunomodulators

The nosological classification (ICD-10)

B19 Viral hepatitis, unspecified: Anemia without hepatitis; Viral hepatitis; Viral hepatitis in children; Infection of the liver; Acute liver infection

D70 Agranulocytosis: Agranulocytosis is hereditary; Aleicia; Aleykocytosis; Agranulocytic angina; Angina agranulocytic; Primary cytopenia

D72 Other disorders of white blood cells: Lymphocytopenia; Hereditary neutropenia

D84.9 Unspecified Immunodeficiency: Pneumonia in immunodeficient states; Autoimmune disease; Autoimmune diseases; Severe immunodeficiency; immune deficiency; Immunodeficiency; immunodeficiency diseases; Immunodeficiency states due to surgery; Immunotherapy for cancer; Immunomodulation; Infections in patients with weakened immune systems; Correction of immune deficiency; Correction of immunodeficiencies; Correction of a weakened immune system; Correction of a weakened immunity in immunodeficient states; Violation of immunity; Violation of the immune status; Immune System Disorders; Primary immunodeficiency; Maintaining immunity; Lowering the body's defenses; Lowering the immunity; Lowering the immunity of colds and infectious diseases; The decrease of the immune status; Lowered resistance to infections; Lowered resistance to infections and colds; Lowered resistance; Immunosuppression; Predisposition to colds; acquired immune deficiencies; Radiation immunodeficiency; The development of immunodeficiency; Immune dysfunction syndrome; immunodeficiency syndrome; primary immunodeficiency syndrome; Reducing the body's defenses; Immunosuppression; Reduced immune defense; Reducing local immunity; Reducing the total body resistance; The decrease in cell-mediated immunity; Reduced resistance to infections in children; Reducing the body's resistance; Reduced resistance; reduced immunity; Status immunodeficiency; Stimulation of the processes of nonspecific immunity; Heavy selective secondary immunodeficiency; immunity Oppression; Primary immunodeficiency

H19.1 Keratitis due to herpes simplex virus, and keratoconjunctivitis (B00.5 +): Recurrent ophthalmoherpes; Ophthalmoherpes; Herpetic keratoconjunctivitis; Herpetic conjunctivitis

J18 Pneumonia without specification of pathogens: Alveolar pneumonia; Community-acquired pneumonia atypical; Community-acquired pneumonia non-pneumococcal; Pneumonia; Inflammation of the lower respiratory tract; Inflammatory lung disease; Shared pneumonia; Respiratory and lung infections; Infections of the lower respiratory tract; Cough with inflammatory diseases of the lungs and bronchi; Croupous pneumonia; Nosocomial pneumonia; Exacerbation of chronic pneumonia; Acute community-acquired pneumonia; Acute pneumonia; Focal pneumonia; Pneumonia abscessing; Pneumonia bacterial; Pneumonia croupy; Pneumonia of focal; Pneumonia with difficulty in sputum discharge; Pneumonia in AIDS patients; Pneumonia in children; Septic pneumonia; Chronic Obstructive Pneumonia; Chronic pneumonia; Lymphoid interstitial pneumonia

Characterization of the substance Sodium nucleate

A mixture of sodium salts of nucleic acids, obtained by hydrolysis of yeast and subsequent purification.

White or slightly grayish-yellowish powder. Easily soluble in water with the formation of opalescent solutions.


Pharmacological action - immunostimulating, regenerating, leukopoietic.

Accelerates regeneration processes, stimulates bone marrow hematopoiesis, incl. Leukopoiesis. It has an immunostimulating effect: it increases the migration and cooperation of T and B lymphocytes, the phagocytic activity of macrophages, the activity of factors of nonspecific resistance.

Effective for diseases that occur against the background of immunodeficiency states or accompanied by their development.

Application of the substance Sodium nucleate

Leukopenia, agranulocytosis, complex therapy of chronic inflammation of the lungs, herpetic keratitis, viral hepatitis, and others.


Hypersensitivity, organic diseases of the heart muscle with a violation of conductivity.

Side effects of Sodium nucleate

CNS depression, bradycardia, dyspnea, allergic reactions.

Routes of administration


Precautions for the substance Sodium nucleate

Treatment is carried out under the control of the immune status.At appointment to patients with a diabetes it is necessary to control the level of glucose in the blood (possible deep hypoglycemia).

Special instructions

In the therapy of herpetic keratitis, the intake is combined with the instillation of a 3% solution into the conjunctival sac of the eye 3 times a day.

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