Instruction for use: Sinepres

Active substance: Hydrochlorothiazide + Dihydroergotoxine + Reserpine

ATX Code C02LA51 reserpine and diuretics combinations with other drugs

Pharmacotherapeutic group:

Sympatholytics in combinations

Diuretics in combination

The nosological classification (ICD-10)

I10 Essential (primary) hypertension

Hypertension, Arterial hypertension, Arterial hypertension crisis course, Essential Hypertension

Primary hypertension, Arterial hypertension, complications of diabetes, hypertension, The sudden increase in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial Hypertension, malignant Hypertension, Hypertonic disease, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, The aggravation of hypertensive disease, Transient hypertension, Isolated systolic hypertension

I15 Secondary hypertension

Arterial hypertension, complications of diabetes, hypertension, The sudden rise in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial hypertension, malignant hypertension, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, hypertensive crisis, The aggravation of hypertensive disease, Transient hypertension, hypertension, Arterial hypertension, Arterial hypertension crisis course, renovascular hypertension, symptomatic hypertension, renal hypertension, Renovascular hypertension, Symptomatic hypertension

Structure and Composition

1 tablet contains 0.6 mg Dihydroergotoxin mesylate, reserpine 0.1 mg and hydrochlorothiazide 10 mg; in blister 10 pcs., in box 5 blisters.

pharmachologic effect

a diuretic, vasodilatory, sympatholytic, sedative.

It reduces the frequency and force of heart contractions, blocks alpha-adrenergic receptors of the arteries, reduces peripheral vascular resistance, promotes the excretion of sodium, chloride, potassium and water.

Indications

Hypertension.

Contraindications

Hypersensitivity, gastric ulcer and duodenal ulcer in the acute phase of ulcerative colitis, severe renal and hepatic failure, bronchospastic syndrome, depression, hypokalemia.

Pregnancy and breast-feeding

Contraindicated during pregnancy. Lactating women during the period of treatment should stop breastfeeding.

Side effects

Anorexia, dry mouth, nausea, vomiting, dizziness, drowsiness, decreased reaction rate. Rarely - visual disturbances, hypokalemia, depression, allergic skin reactions.

Dosing and Administration

Inside - 1 tablet 1-2 times a day (maximum dose - 3 pills / day).

Storage conditions

In a dry, dark place.

Keep out of the reach of children.

shelf life

3 years.

Do not use beyond the expiration date printed on the package.