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Instruction for use: Reactine

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Dosage form: Eye drops; Nasal spray

Actibe substance: Levocabastinum


S01GX02 Levocabastine

Pharmacological groups:


An anticongestants

Ophthalmic products

Composition and release form

1 ml eye drops or nasal spray contains levocabastine 0.5 mg; In bottles-droppers of 4 ml or in bottles with a sprayer of 10 ml, respectively, in a cardboard bundle 1 bottle.

Pharmachologic effect

Mode of action - anti-allergic, antihistamine.

Selectively blocks histamine H1 receptors.


After instillation in the eye, Levocabastine is absorbed slowly and not completely. The concentration in the plasma is too small to have a systemic effect. With a single intranasal injection, 30-40 μg of levocabastine is absorbed, 70% of this amount is excreted mostly unchanged in urine. T1 / 2 35-40 hours.

Indication for the Histimet

Allergic rhinitis and conjunctivitis.



Application in pregnancy and breastfeeding

During pregnancy, it is prescribed only in those cases when the expected positive effect of treatment exceeds the potential risk to the fetus.

Side effects

Irritation of the conjunctiva or nasal mucosa.

Dosing and Administration

Conjunctival (eye drops) 1 drop in each eye or intranasally (nasal spray) - 2 injections into each nasal passage (it should be cleaned first). Apply usually 2 times a day, if necessary - 3-4 times a day.

Precautionary measures

With caution use the spray for violations of kidney function. Burying in the eyes eliminates the wearing of soft (hydrophilic) contact lenses.

Storage conditions of the drug Reactine

At a temperature of 15-30 C.

Keep out of the reach of children.

Shelf life of the drug Reactine

Eye drops 0.5 mg / ml - 2 years.

Eye drops 0.05% - 2 years.

Spray nasal 0.5 mg / ml - 3 years.

Do not use after the expiry date printed on the package.

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