Instruction for use: Proscar
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Active substance:
Finasteride
ATX code
G04CB01 Finasteride
Pharmacological group
Androgens, antiandrogens
Means that affect the metabolism in the prostate gland, and correctors urodynamics
Nosological classification (ICD-10)
N40 Prostatic hyperplasia
Prostate adenoma, BPH, Hypertrophy of the prostate, Hypertrophy of the prostate, Dysuric disorders due to benign prostatic hyperplasia, Dysuria with prostatic adenoma, Benign prostatic hyperplasia, Benign prostatic hyperplasia of stage 1 and 2, Benign prostatic hyperplasia of the first degree, Benign prostatic hyperplasia of II degree, Benign prostatic hypertrophy, Disease of the prostate, Acute urinary retention associated with benign prostatic hyperplasia, Benign prostatic hyperplasia 1 and 2 stages in combination with prostatitis, The paradoxical ishuria
Composition
1 tablet contains finasteride 5 mg; In the contour acheikova packing 14 pcs., In the box 1 or 2 packs.
pharmachologic effect
Pharmacological action - antiandrogenic.
Inhibits 5-alpha-reductase, reduces the biosynthesis of dihydrotestosterone.
Pharmacodynamics
With constant admission, a statistically significant effect is recorded after 3 months (decrease in the volume of the prostate gland), 4 months (increase in the maximum urinary flow rate) and 7 months (decrease in the general symptoms and symptoms of obstruction of the urinary tract).
Pharmacokinetics
It is well absorbed and penetrates into tissues and biofluids, incl. In the ejaculate.
Clinical Pharmacology
Suppression of the formation of dihydrotestosterone is accompanied by a decrease in the volume of the prostate gland, an increase in the maximum urinary flow rate and a decrease in symptoms of obstruction of the urinary tract.
Ineffective in patients with malignant degeneration of the prostate (cancer).
Indications
Prostate adenoma.
Contraindications
Hypersensitivity, children's age.
pregnancy and lactation
Pregnant women should avoid contact with shredded or loose integrity tablets of the drug. Women who can become pregnant, pregnant and nursing mothers should not have sexual contact (without condom) with a partner who accepts Proscar (possibly a violation of the development of the external genital organs in the male fetus).
Side effects
Violation of sexual functions (impotence, decreased libido, decreased ejaculate volume).
Interaction
Clinically significant effects of interaction with other drugs have not been detected.
Dosing and Administration
Inside, 5 mg / day for 6-7 months or more.
Precautionary measures
In patients with a large volume of residual urine and / or a sharply reduced current, careful monitoring of the possible development of obstructive uropathy is necessary.
storage Conditions
In the dark place at a temperature of no higher than 30 ° C.
Keep out of the reach of children.
Shelf Life
2 years.
Do not use after the expiry date printed on the package.