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Instruction for use: Prodep

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Dosage form: capsules

Active substance: Fluoxetine*


N06AB03 Fluoxetin

Pharmacological groups:


The nosological classification (ICD-10)

F32 Depressive episode: Adynamic subdepression; Astheno-adynamic subdepressive states; Asthenoadressive disorder; Astheno-depressive disorder; Asthenodepressive state; Astheno-depressive state; Major Depressive Disorder; Vyaloapatichesky depression with retardation; Double Depression; Depressive pseudodement; Depressive illness; Depressive mood disorder; Depressive disorder; Depressive mood disorder; Depressive state; Depressive disorders; Depressive syndrome; Depressive syndrome larviated; Depressive syndrome in psychoses; Depressed masks; Depression; Depression Depletion; Depression with the phenomena of inhibition within the framework of cyclothymia; Depression is smiling; Involutional depression; Involutionary melancholy; Involutional depression; Manic-depressive disorder; Masked Depression; Melancholic Attack; Neurotic depression; Neurotic depression; Shallow Depression; Organic depression; Organic depressive syndrome; Simple depression; Simple melancholic syndrome; Psychogenic depression; Reactive depression; Reactive depression with moderate psychopathological symptoms; Reactive depressive states; Reactive depression; Recurrent depression; Seasonal depressive syndrome; Severostatic depression; Senile Depression; Symptomatic Depression; Somatogenic depression; Cyclotymic depression; Exogenous depression; Endogenous depression; Endogenous Depressive Conditions; Endogenous Depression; Endogenous depressive syndrome

Composition and release form

1 capsule contains fluoxetine 20 mg; in a blister 10 pcs., in a box of 6 blisters.

Pharmachologic effect

Pharmacological action - antidepressant.


Well absorbed (food intake does not affect bioavailability), is metabolized in the liver, excreted by the kidneys.

Indications for the Prodep

Depression of different etiology, bulimia.


Hypersensitivity, atony of the bladder, kidney failure, prostate adenoma, epilepsy, glaucoma.

Application in pregnancy and lactation


Side effects

Anxiety, nervousness, heat, headache, insomnia, dizziness, drowsiness, fatigue, tremor, dyspeptic disorders (anorexia, dry mouth, nausea, vomiting, diarrhea), dysphonia, decreased libido, hyponatremia, allergic reactions.


Incompatible with MAO inhibitors. Simultaneous use with other antidepressants, as well as tryptophan increases the risk of side effects.

Dosing and Administration

Inside, regardless of food intake, the initial dose - 20 mg once a day (in the morning); if necessary, increase the dose to 40-60 mg / day in 2-3 doses. The maximum dose is 80 mg / day. With bulimia - 60 mg 2-3 times a day. If the kidneys and liver function is impaired, lowering of doses and lengthening of the interval between doses of the drug is necessary.

Precautionary measures

It should be administered with caution in case of impaired liver or kidney function. In patients with diabetes, it may be necessary to adjust the dose of insulin or oral hypoglycemic agents. At least 5 weeks before the start of treatment, it is necessary to abolish MAO inhibitors.

Storage conditions for Prodep

In a dry, the dark place at a temperature of no higher than 30 C.

Keep out of the reach of children.

Shelf life of Prodep

4 years.

Do not use after the expiry date printed on the package.

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