Instruction for use: Phenylpropanolamine (Phenylpropanolaminum)

chemical name (±) - (R *, S *) - a- (1-Aminoethyl) benzenemethanol

Pharmacotherapeutic group:

Regulators appetite

Alpha-adrenoceptor agonists

The nosological classification (ICD-10)

E66 Obesity

Adipoz, overweight, Overweight, Constitutional tendency to obesity, Obesity or overweight, Increased body weight, Tendency to corpulence, Reducing overweight, Exogenous constitutional obesity,Inclined to corpulence

CodeCAS 14838-15-4

Pharmacological effect of Phenylpropanolamine

Pharmachologic effect anorectic, vasoconstriction.

It has sympathomimetic effects. It stimulates the release of norepinephrine from nerve endings stimulates mostly the central alpha-adrenergic receptors, inhibits hypothalamic center of the appetite (anorectic effect).

Indications for Phenylpropanolamine
Decreased appetite, including obesity.

Contraindications for Phenylpropanolamine

Hypersensitivity, ischemic heart disease, heart failure in the phase of decompensation, hypertension, central nervous system diseases, bronchial asthma, glaucoma, hyperthyroidism, diabetes mellitus, prostate hyperplasia, pregnancy, lactation, children's age (12 years).

Side effect

Diarrhoeal phenomenon, coronary artery disease exacerbation, hypertension; headache, tremor, psychomotor disturbances, dizziness, insomnia, irritability.

Interaction

Against the background of propranolol, atenolol, cardiac glycosides may cause arrhythmias. It increases the toxicity of the central nervous system stimulants and MAO inhibitors (agitation, tremors, hypertension). Reserpine effect weakens.

Routes of administration

Inside.