Instruction for use: Normatens

Active substance: Dihydroergocristine + Clopamide + Reserpine

ATX Code C02LA51 reserpine and diuretics combinations with other drugs

Pharmacotherapeutic group:

Sympatholytics in combinations

Diuretics in combination

The nosological classification (ICD-10)

I10 Essential (primary) hypertension

Hypertension, Arterial hypertension, Arterial hypertension crisis course, Essential Hypertension

Primary hypertension, Arterial hypertension, complications of diabetes, hypertension, The sudden increase in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial Hypertension, malignant Hypertension, Hypertonic disease, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, The aggravation of hypertensive disease, Transient hypertension, Isolated systolic hypertension

I15 Secondary hypertension

Arterial hypertension, complications of diabetes, hypertension, The sudden rise in blood pressure, Hypertensive disorders of blood circulation, hypertensive condition, hypertensive crises, hypertension, arterial hypertension, malignant hypertension, Hypertensive crisis, Hypertension, accelerated hypertension, malignant hypertension, hypertensive crisis, The aggravation of hypertensive disease, Transient hypertension, hypertension, Arterial hypertension, Arterial hypertension crisis course, renovascular hypertension, symptomatic hypertension, renal hypertension, Renovascular hypertension, Symptomatic hypertension

Structure and Composition

1 tablet contains 5 mg clopamide, dihydroergocristine (in the form of maleate) 0.5 mg and 0.1 mg of reserpine; in blister 20 pcs.

pharmachologic effect

antihypertensive.

Deplete norepinephrine in adrenergic nerve endings, blocking the alpha-adrenergic receptors.

pharmacodynamics

Increase peripheral vessels, decreases total peripheral vascular resistance increases urinary excretion of sodium and chloride ions, water, reduces the content of sodium ions in the vessel wall, reducing its sensitivity to vasoconstrictive effects.

Indications

Hypertension (primary, secondary).

Contraindications

Hypersensitivity, hypokalemia (resistant to treatment), expressed human liver and kidneys, severe coronary insufficiency, recent myocardial infarction, depression, epilepsy, duodenal ulcer, gastroenteritis, asthma, diabetes, gout.

Side effects

Nausea, vomiting, dizziness, drowsiness, fatigue, muscle weakness, orthostatic hypotension, flushing and swelling of the nasal mucosa, violations of water-electrolyte balance.

Dosing and Administration

Inside, adults - at a dose of 1 tablet per day; in severe forms, or in conditions requiring rapid decline in blood pressure, a daily dose can be increased to 2-3 pills; maintenance therapy - 1 tablet every other day.

Precautionary measures

Be wary appointed in middle and old age; people skills need attention, speed of mental and physical reactions. During treatment is necessary to control the potassium level in serum; long-term therapy is recommended that a diet high in potassium or additional appointment of its products.

Storage conditions

In a dry, dark place at a temperature of 15-25 ° C.

Keep out of the reach of children.

shelf life

5 years.

Do not use beyond the expiration date printed on the package.